R语言

Lecture08 : R在生物信息学中的应用

罗益民

2024-09-20

本节内容一览

  • Part01 R与NGS
  • Part02 Bioconductor及常用生信软件包
  • Part03 R语言与生信绘图

Part01 R与NGS

什么是NGS?

NGS全名为 Next-generation Sequencing(高通量测序技术,二代测序技术)。NGS利用高通量和大规模平行测序,与过往第一代测序技术(即Sanger测序,每次只能针对一条DNA片段进行测序)相比,能让结果维持在高准确性的同时,大幅提升整体测序的效率和降低所需成本。以完成一个人类基因组的测序为例,所需时间从过往10年大幅缩短至只需1天时间,测序成本亦可从约30 亿美元大幅降至约1000美元。

有了NGS的超高通量、可扩展性和速度,在生物信息学与基因数据相结合下,研究人员就能以前所未有的水平来开展生物系统研究,为疾病研究和群体基因组学研究提供有价值的信息;在临床应用方面,还能对癌症样本进行测序,分析稀有体细胞变异及表观遗传学因素,以揭示疾病相关的等位基因。

R语言在生物信息中最为重要的应用就是NGS相关数据分析及可视化。

NGS流程

1. 提取:从样本中分离出核酸(DNA或RNA),通过裂解细胞并纯化遗传物质,得到可用于测序的纯DNA或RNA。

2. 文库制备:将DNA或RNA样品片段化成较小的片段,并向这些片段的末端添加特定的接头(Adaptors),以构建测序文库。

3. 测序:将文库加载到测序平台上,进行测序。常用的测序平台如Illumina使用边合成边测序化学技术,检测单碱基掺入不断生长的DNA链中的位点。

4. 数据分析:测序完成后,需要对产生的大量数据进行分析,包括数据的质量控制、比对、变异检测和结果解释等步骤。

NGS过程中产生的数据文件

  1. 原始测序数据文件(FastQ文件):测序平台生成的原始序列数据和相应的质量分数。通常以.fastq或.fq为文件扩展名。 测序仪器日志文件:
  2. 质量控制(QC)报告文件:通常由QC软件生成,用于评估测序数据的质量。它们可能包括HTML、PDF、图像文件等格式。
  3. 比对文件(BAM或SAM文件):这些文件包含了测序数据与参考基因组比对的结果。SAM是一种文本格式,而BAM格式是SAM的二进制压缩格式,它们都用于存储比对信息。
  4. 变异检测文件(VCF文件):包含了变异检测的结果,包括单核苷酸多态性(SNPs)、插入和缺失等。VCF(Variant Call Format)是一种用于存储基因组变异信息的标准文本格式。
  5. 基因表达量文件:包含基因表达量估计的文件,如.htseq-count或.featureCounts文件。
  6. 统计分析结果文件:包含了统计分析的结果,如差异表达分析、富集分析等,可能包括文本文件、表格文件(如CSV、TSV)等。
  7. 图形和图表文件:展示分析结果的图形和图表,如热图、火山图、曼哈顿图等,包括SVG、PDF、PNG等。
  8. 元数据文件:包含了样本的元数据,如样本信息、实验条件、测序平台等,通常以CSV或Excel格式存储。

NGS研究基本过程

Part02 Bioconductor及常用生信软件包

Bioconductor

Bioconductor 是一个专门存储、分发生信R包的平台,可以把它看成一个R工具包管理组织;里面发布了各种生信分析的R包。Bioconductor建立宗旨: 降低科研人员做生信分析的门槛,提供更方便的工具。可以说Bioconductor已经是做生信分析最得力的工具。

如何学习Bioconductor

1.Bioconductor的Learning部分

Bioconductor上有自己的课程,即Learning部分的Courses and Conferences,课程非常细致。是最官方的资料。软件包的作者亲自告诉你该怎么用。包含单细胞测序、甲基化数据分析、CNV、SNP、RNA-Seq分析等等….非常全面。里面所有的course完全免费。

2. 常用工作流(common workflow)

Bioconductor的工作流程(workflows)是一系列预定义的步骤,它们将不同的分析工具和方法组合在一起,使得常用分析成为了标准流程。目前的标准工作流已经有40个,内容涵盖芯片分析、基因表达分析、免疫共沉淀chipseq分析等。内容持续更新,可直接完成实际工作任务。

3. 软件包的详情页面

Bioconducor每个软件包的详情页面都有详细的说明,html格式的一般为教程,PDF格式的是说明文档,RScript里也提供了详细的脚本,是快速了解一个包的不二之选:

Bioconductor安装

先安装BiocManager。然后就可以使用BiocManager::install(包名)安装需要的Bioconductor软件包了。

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
BiocManager::install("$package")

CRAN和Bioconductor的关系:

  1. Bioconductor的包需要使用BiocManager安装,后者需要从CRAN下载
  2. BiocManager.install()方法执行时,首先去Bioconductor仓库寻找,如果找不到,会自动去CRAN寻找

自定义.Rprofile以加快下载速度

.Rprofile 是一个用于R语言的配置文件,它允许用户设置全局选项和执行启动时的脚本。当你打开一个新的R会话时, R会依次从以下路径寻找该文件并执行:

  1. 当前工作空间文件夹:使用getwd()查看
  2. R_Home文件夹:使用R.home()查看
  3. 操作系统Home文件夹:使用path.expand("~")查看

当找到第一个.Rprofile文件后,便不会再往下寻找。

可以在这些目录下手动建立.Rprofile,也可通过以下命令直接编辑:

file.edit(file.path("~", ".Rprofile")) # edit .Rprofile in HOME
file.edit(".Rprofile") # edit project specific .Rprofile 

可在.Rprofile中设定bioconductor镜像源以加快下载速度。

options(BioC_mirror="https://mirrors.tuna.tsinghua.edu.cn/bioconductor")
options("repos" = c(CRAN="https://mirrors.tuna.tsinghua.edu.cn/CRAN/","https://mirrors.qlu.edu.cn/CRAN/"))

重启R后使用以下命令检查是否生效:

getOption("BioC_mirror")

Bioconductor软件包

截至目前(2024)已有31万个包。网站列出了下载量最高的包。仅2024年就新增了三万六千多个包:

 2009  2010  2011  2012  2013  2014  2015  2016  2017  2018  2019  2020  2021  2022  2023  2024 
 4927  5889  7345  8788 10641 13185 15431 18187 20514 23016 25540 28691 31382 33280 35308 36491

部分包简要介绍如下:

批量安装常用包

可以用以下脚本一次性安装常用包。

Bioconductor上的包一般都比较大,安装前使用.libPaths()检查本机R包安装路径,确保有足够的空间。

options(BioC_mirror="https://mirrors.tuna.tsinghua.edu.cn/bioconductor")
options("repos" = c(CRAN="https://mirrors.tuna.tsinghua.edu.cn/CRAN/","https://mirrors.qlu.edu.cn/CRAN/"))

packages <-  c(
  "Biostrings","GenomicRanges","SummarizedExperiment",
  "limma","edgeR","DESeq2",
  "GEOquery","TCGAbiolinks","BSgenome.Hsapiens.UCSC.hg38",
  "org.Hs.eg.db","KEGG.db",
  "GSEABase","GSRA",
  "enrichplot","clusterProfiler","survival","survminer"
)

package.new <- packages[!packages %in% installed.packages()[,"Package"]]

print(paste("to install:",package.new, sep = " "))

if(T){
  if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")
  lapply(package.new, function(x){
    BiocManager::install(x,ask = F,update = F)
  })
  print(paste(package.new, "installed", sep = " "))
} 

基因组:序列获取

library(BSgenome.Hsapiens.NCBI.GRCh38)
genome <- BSgenome.Hsapiens.NCBI.GRCh38
length(genome) 
[1] 455
# 查看所有序列名称,除了染色体序列外,其余的被称为unlocalized contigs,它们是基因组中的一部分,但在当前的基因组组装版本中,尚未能够将它们精确地定位到特定的染色体上
seqnames(genome) 
  [1] "1"                                  "2"                                 
  [3] "3"                                  "4"                                 
  [5] "5"                                  "6"                                 
  [7] "7"                                  "8"                                 
  [9] "9"                                  "10"                                
 [11] "11"                                 "12"                                
 [13] "13"                                 "14"                                
 [15] "15"                                 "16"                                
 [17] "17"                                 "18"                                
 [19] "19"                                 "20"                                
 [21] "21"                                 "22"                                
 [23] "X"                                  "Y"                                 
 [25] "MT"                                 "HSCHR1_CTG1_UNLOCALIZED"           
 [27] "HSCHR1_CTG2_UNLOCALIZED"            "HSCHR1_CTG3_UNLOCALIZED"           
 [29] "HSCHR1_CTG4_UNLOCALIZED"            "HSCHR1_CTG5_UNLOCALIZED"           
 [31] "HSCHR1_CTG6_UNLOCALIZED"            "HSCHR1_CTG7_UNLOCALIZED"           
 [33] "HSCHR1_CTG8_UNLOCALIZED"            "HSCHR1_CTG9_UNLOCALIZED"           
 [35] "HSCHR2_RANDOM_CTG1"                 "HSCHR2_RANDOM_CTG2"                
 [37] "HSCHR3UN_CTG2"                      "HSCHR4_RANDOM_CTG4"                
 [39] "HSCHR5_RANDOM_CTG1"                 "HSCHR9_UNLOCALIZED_CTG1"           
 [41] "HSCHR9_UNLOCALIZED_CTG2"            "HSCHR9_UNLOCALIZED_CTG3"           
 [43] "HSCHR9_UNLOCALIZED_CTG4"            "HSCHR11_CTG1_UNLOCALIZED"          
 [45] "HSCHR14_CTG1_UNLOCALIZED"           "HSCHR14_CTG2_UNLOCALIZED"          
 [47] "HSCHR14_CTG3_UNLOCALIZED"           "HSCHR14_CTG4_UNLOCALIZED"          
 [49] "HSCHR14_CTG5_UNLOCALIZED"           "HSCHR14_CTG6_UNLOCALIZED"          
 [51] "HSCHR14_CTG7_UNLOCALIZED"           "HSCHR14_CTG8_UNLOCALIZED"          
 [53] "HSCHR15_RANDOM_CTG1"                "HSCHR16_RANDOM_CTG1"               
 [55] "HSCHR17_RANDOM_CTG3"                "HSCHR17_RANDOM_CTG4"               
 [57] "HSCHR17_RANDOM_CTG5"                "HSCHR22_UNLOCALIZED_CTG1"          
 [59] "HSCHR22_UNLOCALIZED_CTG2"           "HSCHR22_UNLOCALIZED_CTG3"          
 [61] "HSCHR22_UNLOCALIZED_CTG4"           "HSCHR22_UNLOCALIZED_CTG5"          
 [63] "HSCHR22_UNLOCALIZED_CTG6"           "HSCHR22_UNLOCALIZED_CTG7"          
 [65] "HSCHR22_UNLOCALIZED_CTG8"           "HSCHR22_UNLOCALIZED_CTG9"          
 [67] "HSCHRY_RANDOM_CTG1"                 "HSCHRUN_RANDOM_100"                
 [69] "HSCHRUN_RANDOM_101"                 "HSCHRUN_RANDOM_102"                
 [71] "HSCHRUN_RANDOM_103"                 "HSCHRUN_RANDOM_104"                
 [73] "HSCHRUN_RANDOM_105"                 "HSCHRUN_RANDOM_106"                
 [75] "HSCHRUN_RANDOM_107"                 "HSCHRUN_RANDOM_108"                
 [77] "HSCHRUN_RANDOM_109"                 "HSCHRUN_RANDOM_110"                
 [79] "HSCHRUN_RANDOM_111"                 "HSCHRUN_RANDOM_112"                
 [81] "HSCHRUN_RANDOM_113"                 "HSCHRUN_RANDOM_114"                
 [83] "HSCHRUN_RANDOM_115"                 "HSCHRUN_RANDOM_116"                
 [85] "HSCHRUN_RANDOM_117"                 "HSCHRUN_RANDOM_118"                
 [87] "HSCHRUN_RANDOM_119"                 "HSCHRUN_RANDOM_120"                
 [89] "HSCHRUN_RANDOM_121"                 "HSCHRUN_RANDOM_122"                
 [91] "HSCHRUN_RANDOM_123"                 "HSCHRUN_RANDOM_124"                
 [93] "HSCHRUN_RANDOM_125"                 "HSCHRUN_RANDOM_126"                
 [95] "HSCHRUN_RANDOM_127"                 "HSCHRUN_RANDOM_128"                
 [97] "HSCHRUN_RANDOM_129"                 "HSCHRUN_RANDOM_130"                
 [99] "HSCHRUN_RANDOM_131"                 "HSCHRUN_RANDOM_132"                
[101] "HSCHRUN_RANDOM_133"                 "HSCHRUN_RANDOM_134"                
[103] "HSCHRUN_RANDOM_135"                 "HSCHRUN_RANDOM_136"                
[105] "HSCHRUN_RANDOM_137"                 "HSCHRUN_RANDOM_138"                
[107] "HSCHRUN_RANDOM_139"                 "HSCHRUN_RANDOM_140"                
[109] "HSCHRUN_RANDOM_141"                 "HSCHRUN_RANDOM_142"                
[111] "HSCHRUN_RANDOM_143"                 "HSCHRUN_RANDOM_144"                
[113] "HSCHRUN_RANDOM_145"                 "HSCHRUN_RANDOM_146"                
[115] "HSCHRUN_RANDOM_147"                 "HSCHRUN_RANDOM_148"                
[117] "HSCHRUN_RANDOM_149"                 "HSCHRUN_RANDOM_154"                
[119] "HSCHRUN_RANDOM_155"                 "HSCHRUN_RANDOM_156"                
[121] "HSCHRUN_RANDOM_157"                 "HSCHRUN_RANDOM_158"                
[123] "HSCHRUN_RANDOM_159"                 "HSCHRUN_RANDOM_160"                
[125] "HSCHRUN_RANDOM_161"                 "HSCHRUN_RANDOM_162"                
[127] "HSCHRUN_RANDOM_163"                 "HSCHRUN_RANDOM_164"                
[129] "HSCHRUN_RANDOM_165"                 "HSCHRUN_RANDOM_166"                
[131] "HSCHRUN_RANDOM_167"                 "HSCHRUN_RANDOM_168"                
[133] "HSCHRUN_RANDOM_169"                 "HSCHRUN_RANDOM_170"                
[135] "HSCHRUN_RANDOM_171"                 "HSCHRUN_RANDOM_172"                
[137] "HSCHRUN_RANDOM_173"                 "HSCHRUN_RANDOM_174"                
[139] "HSCHRUN_RANDOM_175"                 "HSCHRUN_RANDOM_176"                
[141] "HSCHRUN_RANDOM_177"                 "HSCHRUN_RANDOM_178"                
[143] "HSCHRUN_RANDOM_179"                 "HSCHRUN_RANDOM_180"                
[145] "HSCHRUN_RANDOM_181"                 "HSCHRUN_RANDOM_182"                
[147] "HSCHRUN_RANDOM_183"                 "HSCHRUN_RANDOM_184"                
[149] "HSCHRUN_RANDOM_185"                 "HSCHRUN_RANDOM_186"                
[151] "HSCHRUN_RANDOM_187"                 "HSCHRUN_RANDOM_188"                
[153] "HSCHRUN_RANDOM_189"                 "HSCHRUN_RANDOM_190"                
[155] "HSCHRUN_RANDOM_191"                 "HSCHRUN_RANDOM_192"                
[157] "HSCHRUN_RANDOM_193"                 "HSCHRUN_RANDOM_194"                
[159] "HSCHRUN_RANDOM_195"                 "HSCHRUN_RANDOM_196"                
[161] "HSCHRUN_RANDOM_197"                 "HSCHRUN_RANDOM_198"                
[163] "HSCHRUN_RANDOM_199"                 "HSCHRUN_RANDOM_200"                
[165] "HSCHRUN_RANDOM_201"                 "HSCHRUN_RANDOM_202"                
[167] "HSCHRUN_RANDOM_203"                 "HSCHRUN_RANDOM_204"                
[169] "HSCHRUN_RANDOM_CTG1"                "HSCHRUN_RANDOM_CTG10"              
[171] "HSCHRUN_RANDOM_CTG11"               "HSCHRUN_RANDOM_CTG16"              
[173] "HSCHRUN_RANDOM_CTG17"               "HSCHRUN_RANDOM_CTG19"              
[175] "HSCHRUN_RANDOM_CTG2"                "HSCHRUN_RANDOM_CTG20"              
[177] "HSCHRUN_RANDOM_CTG21"               "HSCHRUN_RANDOM_CTG22"              
[179] "HSCHRUN_RANDOM_CTG23"               "HSCHRUN_RANDOM_CTG24"              
[181] "HSCHRUN_RANDOM_CTG25"               "HSCHRUN_RANDOM_CTG26"              
[183] "HSCHRUN_RANDOM_CTG27"               "HSCHRUN_RANDOM_CTG28"              
[185] "HSCHRUN_RANDOM_CTG29"               "HSCHRUN_RANDOM_CTG30"              
[187] "HSCHRUN_RANDOM_CTG33"               "HSCHRUN_RANDOM_CTG34"              
[189] "HSCHRUN_RANDOM_CTG35"               "HSCHRUN_RANDOM_CTG36"              
[191] "HSCHRUN_RANDOM_CTG4"                "HSCHRUN_RANDOM_CTG42"              
[193] "HSCHRUN_RANDOM_CTG6"                "HSCHRUN_RANDOM_CTG9"               
[195] "HSCHR1_1_CTG3"                      "HSCHR1_2_CTG3"                     
[197] "HSCHR1_1_CTG11"                     "HSCHR1_4_CTG31"                    
[199] "HSCHR1_1_CTG31"                     "HSCHR1_2_CTG31"                    
[201] "HSCHR1_3_CTG31"                     "HSCHR1_4_CTG32_1"                  
[203] "HSCHR1_3_CTG32_1"                   "HSCHR1_1_CTG32_1"                  
[205] "HSCHR1_2_CTG32_1"                   "HSCHR2_2_CTG1"                     
[207] "HSCHR2_3_CTG1"                      "HSCHR2_4_CTG1"                     
[209] "HSCHR2_1_CTG1"                      "HSCHR2_1_CTG5"                     
[211] "HSCHR2_1_CTG7"                      "HSCHR2_5_CTG7_2"                   
[213] "HSCHR2_4_CTG7_2"                    "HSCHR2_3_CTG7_2"                   
[215] "HSCHR2_2_CTG7_2"                    "HSCHR2_1_CTG7_2"                   
[217] "HSCHR2_3_CTG15"                     "HSCHR2_1_CTG15"                    
[219] "HSCHR3_1_CTG1"                      "HSCHR3_3_CTG1"                     
[221] "HSCHR3_4_CTG2_1"                    "HSCHR3_1_CTG2_1"                   
[223] "HSCHR3_2_CTG2_1"                    "HSCHR3_3_CTG2_1"                   
[225] "HSCHR3_5_CTG2_1"                    "HSCHR3_1_CTG3"                     
[227] "HSCHR3_2_CTG3"                      "HSCHR3_9_CTG3"                     
[229] "HSCHR4_1_CTG4"                      "HSCHR4_1_CTG6"                     
[231] "HSCHR4_1_CTG8_1"                    "HSCHR4_1_CTG9"                     
[233] "HSCHR4_4_CTG12"                     "HSCHR4_1_CTG12"                    
[235] "HSCHR4_2_CTG12"                     "HSCHR4_5_CTG12"                    
[237] "HSCHR4_3_CTG12"                     "HSCHR5_5_CTG1"                     
[239] "HSCHR5_4_CTG1"                      "HSCHR5_3_CTG1"                     
[241] "HSCHR5_1_CTG1"                      "HSCHR5_2_CTG1"                     
[243] "HSCHR5_6_CTG1"                      "HSCHR5_2_CTG1_1"                   
[245] "HSCHR5_3_CTG1_1"                    "HSCHR5_4_CTG1_1"                   
[247] "HSCHR5_1_CTG5"                      "HSCHR5_2_CTG5"                     
[249] "HSCHR6_MHC_APD_CTG1"                "HSCHR6_1_CTG7"                     
[251] "HSCHR6_1_CTG6"                      "HSCHR6_1_CTG2"                     
[253] "HSCHR6_1_CTG8"                      "HSCHR6_1_CTG9"                     
[255] "HSCHR6_1_CTG3"                      "HSCHR6_1_CTG4"                     
[257] "HSCHR6_1_CTG5"                      "HSCHR7_1_CTG1"                     
[259] "HSCHR7_2_CTG4_4"                    "HSCHR7_1_CTG4_4"                   
[261] "HSCHR7_1_CTG6"                      "HSCHR7_2_CTG6"                     
[263] "HSCHR7_3_CTG6"                      "HSCHR7_2_CTG7"                     
[265] "HSCHR7_1_CTG7"                      "HSCHR8_4_CTG1"                     
[267] "HSCHR8_2_CTG1"                      "HSCHR8_1_CTG1"                     
[269] "HSCHR8_8_CTG1"                      "HSCHR8_3_CTG1"                     
[271] "HSCHR8_9_CTG1"                      "HSCHR8_1_CTG6"                     
[273] "HSCHR8_1_CTG7"                      "HSCHR8_5_CTG7"                     
[275] "HSCHR8_6_CTG7"                      "HSCHR8_4_CTG7"                     
[277] "HSCHR8_3_CTG7"                      "HSCHR8_2_CTG7"                     
[279] "HSCHR9_1_CTG1"                      "HSCHR9_1_CTG2"                     
[281] "HSCHR9_1_CTG3"                      "HSCHR9_1_CTG4"                     
[283] "HSCHR9_1_CTG5"                      "HSCHR10_1_CTG1"                    
[285] "HSCHR10_1_CTG3"                     "HSCHR10_1_CTG2"                    
[287] "HSCHR10_1_CTG4"                     "HSCHR11_1_CTG8"                    
[289] "HSCHR11_1_CTG6"                     "HSCHR11_1_CTG7"                    
[291] "HSCHR11_1_CTG5"                     "HSCHR11_1_CTG1_1"                  
[293] "HG142_HG150_NOVEL_TEST"             "HG151_NOVEL_TEST"                  
[295] "HSCHR11_1_CTG3"                     "HSCHR11_1_CTG2"                    
[297] "HSCHR12_1_CTG1"                     "HSCHR12_2_CTG2"                    
[299] "HSCHR12_5_CTG2"                     "HSCHR12_1_CTG2"                    
[301] "HSCHR12_4_CTG2"                     "HSCHR12_1_CTG2_1"                  
[303] "HSCHR12_2_CTG2_1"                   "HSCHR12_3_CTG2_1"                  
[305] "HSCHR12_6_CTG2_1"                   "HSCHR12_4_CTG2_1"                  
[307] "HSCHR12_5_CTG2_1"                   "HSCHR12_7_CTG2_1"                  
[309] "HSCHR13_1_CTG3"                     "HSCHR13_1_CTG2"                    
[311] "HSCHR13_1_CTG6"                     "HSCHR13_1_CTG4"                    
[313] "HSCHR13_1_CTG1"                     "HSCHR13_1_CTG5"                    
[315] "HSCHR14_1_CTG1"                     "HSCHR14_7_CTG1"                    
[317] "HSCHR14_2_CTG1"                     "HSCHR14_3_CTG1"                    
[319] "HSCHR15_1_CTG1"                     "HSCHR15_3_CTG3"                    
[321] "HSCHR15_1_CTG3"                     "HSCHR15_1_CTG8"                    
[323] "HSCHR15_3_CTG8"                     "HSCHR15_2_CTG8"                    
[325] "HSCHR15_5_CTG8"                     "HSCHR16_CTG2"                      
[327] "HSCHR16_4_CTG1"                     "HSCHR16_3_CTG1"                    
[329] "HSCHR16_1_CTG1"                     "HSCHR16_1_CTG3_1"                  
[331] "HSCHR16_2_CTG3_1"                   "HSCHR17_1_CTG1"                    
[333] "HSCHR17_2_CTG2"                     "HSCHR17_1_CTG2"                    
[335] "HSCHR17_7_CTG4"                     "HSCHR17_4_CTG4"                    
[337] "HSCHR17_5_CTG4"                     "HSCHR17_1_CTG4"                    
[339] "HSCHR17_1_CTG5"                     "HSCHR17_2_CTG4"                    
[341] "HSCHR17_8_CTG4"                     "HSCHR17_9_CTG4"                    
[343] "HSCHR17_3_CTG4"                     "HSCHR17_1_CTG9"                    
[345] "HSCHR18_4_CTG1_1"                   "HSCHR18_1_CTG1_1"                  
[347] "HSCHR18_2_CTG1_1"                   "HSCHR18_2_CTG2"                    
[349] "HSCHR18_1_CTG2"                     "HSCHR18_1_CTG2_1"                  
[351] "HSCHR18_2_CTG2_1"                   "HSCHR18_3_CTG2_1"                  
[353] "HSCHR19_5_CTG2"                     "HSCHR19_4_CTG2"                    
[355] "HSCHR19_1_CTG2"                     "HSCHR19_2_CTG2"                    
[357] "HSCHR19_3_CTG2"                     "HSCHR19_1_CTG3_1"                  
[359] "HSCHR19_2_CTG3_1"                   "HSCHR19_3_CTG3_1"                  
[361] "HSCHR19LRC_COX1_CTG3_1"             "HSCHR20_1_CTG1"                    
[363] "HSCHR20_1_CTG2"                     "HSCHR20_1_CTG4"                    
[365] "HSCHR20_1_CTG3"                     "HSCHR21_1_CTG1_1"                  
[367] "HSCHR21_8_CTG1_1"                   "HSCHR21_6_CTG1_1"                  
[369] "HSCHR21_2_CTG1_1"                   "HSCHR21_3_CTG1_1"                  
[371] "HSCHR21_4_CTG1_1"                   "HSCHR21_5_CTG2"                    
[373] "HSCHR22_1_CTG3"                     "HSCHR22_1_CTG6"                    
[375] "HSCHR22_1_CTG7"                     "HSCHR22_1_CTG4"                    
[377] "HSCHR22_1_CTG5"                     "HSCHR22_1_CTG2"                    
[379] "HSCHR22_1_CTG1"                     "HSCHRX_1_CTG3"                     
[381] "HSCHRX_2_CTG12"                     "HSCHR1_ALT2_1_CTG32_1"             
[383] "HSCHR2_2_CTG7"                      "HSCHR2_2_CTG15"                    
[385] "HSCHR3_3_CTG3"                      "HSCHR4_6_CTG12"                    
[387] "HSCHR5_1_CTG1_1"                    "HSCHR5_3_CTG5"                     
[389] "HSCHR6_MHC_COX_CTG1"                "HSCHR7_2_CTG1"                     
[391] "HSCHR8_6_CTG1"                      "HSCHR8_5_CTG1"                     
[393] "HSCHR11_2_CTG1"                     "HSCHR11_2_CTG1_1"                  
[395] "HSCHR12_3_CTG2"                     "HSCHR15_2_CTG3"                    
[397] "HSCHR15_4_CTG8"                     "HSCHR17_2_CTG1"                    
[399] "HSCHR17_3_CTG2"                     "HSCHR17_10_CTG4"                   
[401] "HSCHR17_6_CTG4"                     "HSCHR17_2_CTG5"                    
[403] "HSCHR18_ALT21_CTG2_1"               "HSCHR18_ALT2_CTG2_1"               
[405] "HSCHR19LRC_COX2_CTG3_1"             "HSCHR22_2_CTG1"                    
[407] "HSCHRX_2_CTG3"                      "HSCHR3_4_CTG3"                     
[409] "HSCHR4_7_CTG12"                     "HSCHR6_MHC_DBB_CTG1"               
[411] "HSCHR8_7_CTG1"                      "HSCHR11_3_CTG1"                    
[413] "HSCHR19LRC_LRC_I_CTG3_1"            "HSCHR22_3_CTG1"                    
[415] "HSCHR3_5_CTG3"                      "HSCHR6_MHC_MANN_CTG1"              
[417] "HSCHR19LRC_LRC_J_CTG3_1"            "HSCHR3_6_CTG3"                     
[419] "HSCHR6_MHC_MCF_CTG1"                "HSCHR19LRC_LRC_S_CTG3_1"           
[421] "HSCHR3_7_CTG3"                      "HSCHR6_MHC_QBL_CTG1"               
[423] "HSCHR19LRC_LRC_T_CTG3_1"            "HSCHR3_8_CTG3"                     
[425] "HSCHR6_MHC_SSTO_CTG1"               "HSCHR19LRC_PGF1_CTG3_1"            
[427] "HSCHR6_8_CTG1"                      "HSCHR19LRC_PGF2_CTG3_1"            
[429] "HSCHR19_4_CTG3_1"                   "HSCHR19KIR_FH15_B_HAP_CTG3_1"      
[431] "HSCHR19KIR_G085_A_HAP_CTG3_1"       "HSCHR19KIR_G085_BA1_HAP_CTG3_1"    
[433] "HSCHR19KIR_G248_A_HAP_CTG3_1"       "HSCHR19KIR_G248_BA2_HAP_CTG3_1"    
[435] "HSCHR19KIR_GRC212_AB_HAP_CTG3_1"    "HSCHR19KIR_GRC212_BA1_HAP_CTG3_1"  
[437] "HSCHR19KIR_LUCE_A_HAP_CTG3_1"       "HSCHR19KIR_LUCE_BDEL_HAP_CTG3_1"   
[439] "HSCHR19KIR_RSH_A_HAP_CTG3_1"        "HSCHR19KIR_RSH_BA2_HAP_CTG3_1"     
[441] "HSCHR19KIR_T7526_A_HAP_CTG3_1"      "HSCHR19KIR_T7526_BDEL_HAP_CTG3_1"  
[443] "HSCHR19KIR_ABC08_A1_HAP_CTG3_1"     "HSCHR19KIR_ABC08_AB_HAP_C_P_CTG3_1"
[445] "HSCHR19KIR_ABC08_AB_HAP_T_P_CTG3_1" "HSCHR19KIR_FH05_A_HAP_CTG3_1"      
[447] "HSCHR19KIR_FH05_B_HAP_CTG3_1"       "HSCHR19KIR_FH06_A_HAP_CTG3_1"      
[449] "HSCHR19KIR_FH06_BA1_HAP_CTG3_1"     "HSCHR19KIR_FH08_A_HAP_CTG3_1"      
[451] "HSCHR19KIR_FH08_BAX_HAP_CTG3_1"     "HSCHR19KIR_FH13_A_HAP_CTG3_1"      
[453] "HSCHR19KIR_FH13_BA2_HAP_CTG3_1"     "HSCHR19KIR_FH15_A_HAP_CTG3_1"      
[455] "HSCHR19KIR_RP5_B_HAP_CTG3_1"       

IRanges 和 GRanges 是Bioconductor中用于基因组数据分析的两个核心数据类型。

  • IRanges 定义了整数区间(integer ranges),用于表示基因组上的位置信息。它由两个整数参数定义:起始位置(start)和结束位置(end),表示一个连续的整数区间。
  • GRanges 是 IRanges 的扩展,它不仅包含了区间信息,还包含了染色体名称(seqnames)、链的方向(strand)等基因组特定的信息。
gr <- GRanges("1", IRanges(1e6 + c(1,101,201), width=100), strand="-")
gr
GRanges object with 3 ranges and 0 metadata columns:
      seqnames          ranges strand
         <Rle>       <IRanges>  <Rle>
  [1]        1 1000001-1000100      -
  [2]        1 1000101-1000200      -
  [3]        1 1000201-1000300      -
  -------
  seqinfo: 1 sequence from an unspecified genome; no seqlengths
# 使用getSeq获得基因序列
dna <- getSeq(Hsapiens, gr)
dna
DNAStringSet object of length 3:
    width seq
[1]   100 CGCGCGGGCCTGGAGCCGGGATCCGCCCTAGGGG...AGCCCGCCCGTGGTCCGTGGCGGCGCGCTCCAC
[2]   100 GCGGCCGTCGATTGGCTGGGGCGAGTGTGGGAAA...GCGAGGCCTTAAATAGGGAAACGGCCTGAGGCG
[3]   100 GTGTCGGAGGGGGGCGCGGGCGGGGGCCCCGCAT...CGAGGCGTGACTGACAGCGAGCGGGGGAGGAGC

基因组:Biostrings

library(Biostrings)
dna[[1]]
100-letter DNAString object
seq: CGCGCGGGCCTGGAGCCGGGATCCGCCCTAGGGGCT...GCCAGCCCGCCCGTGGTCCGTGGCGGCGCGCTCCAC
dna1 <- dna[[1]]
# 反向链
rev(dna1)
100-letter DNAString object
seq: CACCTCGCGCGGCGGTGCCTGGTGCCCGCCCGACCG...TCGGGGATCCCGCCTAGGGCCGAGGTCCGGGCGCGC
# 反向互补链
reverseComplement(dna1)
100-letter DNAString object
seq: GTGGAGCGCGCCGCCACGGACCACGGGCGGGCTGGC...AGCCCCTAGGGCGGATCCCGGCTCCAGGCCCGCGCG
# 计算GC含量
letterFrequency(dna1,c("G", "C"), as.prob = TRUE)
   G    C 
0.38 0.45 
# 翻译蛋白质
translate(dna1, no.init.codon=TRUE)
33-letter AAString object
seq: RAGLEPGSALGARIAARSPLARQPARGPWRRAP
# 正则查找
match <- matchPattern("GCNNNT",dna1, fixed=FALSE)
as.matrix(match)
     [,1] [,2] [,3] [,4] [,5] [,6]
[1,] "G"  "C"  "C"  "G"  "C"  "T" 
[2,] "G"  "C"  "C"  "C"  "G"  "T" 
# 序列比对
pairwiseAlignment(dna[[1]], dna[[2]], 
                  substitutionMatrix = nucleotideSubstitutionMatrix(match = 9, mismatch = -6, baseOnly = TRUE), 
                  gapOpening = 0, gapExtension = -2, 
                  type = "global")
Global PairwiseAlignmentsSingleSubject (1 of 1)
pattern: -CG-C-G-CG---GGCCTGG-AGCCG-GGATCCG...T-G-G-T-CCGTGG---CGGCGC-GCTCCA--C-
subject: GCGGCCGTCGATTGGC-TGGG-GC-GAG--T--G...TA-A-ATA--G-GGAAACGGC-CTG----AGGCG
score: 432 

面向对象编程(OOP)

为什么需要 OOP?

考虑以下代码:

print <- function(x) {
  if (typeof(x)=="character") {
    # 打印字符串
  } else if (typeof(x)=="integer")) {
    # 打印向量
  }  
}

此方法的另一个问题是,只有函数的作者才能在其中添加新类型。这降低了灵活性,因为希望 print 支持自己的类的开发人员需要联系 print 函数的作者。

面向对象编程允许我们为每个类单独实现 print 函数。

print <- function(x, ...) {
  # 一般实现
}

print.character <- function(x, ...) {
  # 字符串打印实现
}

print.int <- function(x, ...) {
  # 向量打印实现
}

面向对象编程还可以通过封装、多态性、抽象和继承进一步地扩展父类定义,使得代码:

  1. 更加模块化 - 我们有多个较小的函数,而不是一个大函数,这提高了可读性并使测试更容易。

  2. 灵活 - 其他用户现在可以添加自己的打印功能,而无需修改任何现有功能。

R 中的 OOP

Bioconductor以及现代R中有很多库/包都使用了OOP。但由于历史原因,R中的面向对象编程有不同的实现版本:

Base R 提供三种 OOP 系统:S3、S4 和参考类 (RC),CRAN 包提供了许多其他 OOP 系统:

  1. \(S3\) 类系统是 R 的第一个 OOP系统,R语言中最简单的面向对象系统,它基于使用泛型函数和方法的简单机制。。

  2. \(S4\) 类系统比S3更为严格和正式。在S4中,类和方法必须显式定义,并且有更严格的继承和方法覆盖规则。S4类提供了更强大的封装和类型检查功能。

  3. \(RC\) 类系统是R语言中的另一种面向对象系统,它提供了类似于传统面向对象编程语言的特性,如构造函数、方法、继承等。

  4. \(R6\) 类系统是一种更现代的面向对象编程方式,它提供了类似于RC类的特性,但是更加灵活和易于使用。

SummarizedExperiment:介绍

SummarizedExperiment 是一个在生物信息学和基因组学中常用的R包,它提供了一个容器(S4类)1,用于存储基于测序的实验数据,如RNA-Seq 以及ChIp-Seq。

SummarizedExperiment 包中包含两个类:

  1. SummarizedExperiment:是一个矩阵样的容器,每一行代表感兴趣的特征,如基因,转录本,外显子等,每一列则代表样本(sample)。每个对象可以包含一个或者多个实验(assay),而它们每一个都用类矩阵的对象表示。
  2. RangedSummarizedExperiment:是 SummarizedExperiment 的子类,所以后者所有的方法在 RangedSummarizedExperiment 中也适用。两者最主要的区别在于 RangedSummarizedExperiment 中的每一行均为 genomic ranges,而不是 包含特征的数据框

SummarizedExperiment:结构

  1. Assay: 数据
  2. ColData:样本信息
  3. RowData/RowRange:基因信息

SummarizedExperiment:实验(Assays)

library(SummarizedExperiment)
# airway包含来自气道平滑肌 RNA-Seq 实验的示例数据集 内含含8个不同实验和64,102个基因转录本的实验计数数据
data(airway, package="airway")
airway
class: RangedSummarizedExperiment 
dim: 63677 8 
metadata(1): ''
assays(1): counts
rownames(63677): ENSG00000000003 ENSG00000000005 ... ENSG00000273492
  ENSG00000273493
rowData names(10): gene_id gene_name ... seq_coord_system symbol
colnames(8): SRR1039508 SRR1039509 ... SRR1039520 SRR1039521
colData names(9): SampleName cell ... Sample BioSample
assays(airway)$counts
                SRR1039508 SRR1039509 SRR1039512 SRR1039513 SRR1039516
ENSG00000000003        679        448        873        408       1138
ENSG00000000005          0          0          0          0          0
ENSG00000000419        467        515        621        365        587
ENSG00000000457        260        211        263        164        245
ENSG00000000460         60         55         40         35         78
ENSG00000000938          0          0          2          0          1
ENSG00000000971       3251       3679       6177       4252       6721
ENSG00000001036       1433       1062       1733        881       1424
ENSG00000001084        519        380        595        493        820
ENSG00000001167        394        236        464        175        658
ENSG00000001460        172        168        264        118        241
ENSG00000001461       2112       1867       5137       2657       2735
ENSG00000001497        524        488        638        357        676
ENSG00000001561         71         51        211        156         23
ENSG00000001617        555        394        905        415        727
ENSG00000001626         10          2          9          2         10
ENSG00000001629       1660       1251       2259       1079       2462
ENSG00000001630         59         54         66         23         84
ENSG00000001631        729        692        943        475       1034
ENSG00000002016        201        161        256         99        268
ENSG00000002079          3          0          3          1          4
ENSG00000002330        206        174        184        111        194
ENSG00000002549       1459       1294       1317        998       1451
ENSG00000002586       7507       7203       9501       6214      10973
ENSG00000002587          2          0          1          0          0
ENSG00000002726          0          0          1          0          0
ENSG00000002745          4          6         22         10          2
ENSG00000002746        151        139        117         65         90
ENSG00000002822        411        303        446        195        445
ENSG00000002834       6314       6364       7831       5809       6677
ENSG00000002919        234        246        298        211        217
ENSG00000002933       1254       1508        636        431         25
ENSG00000003056       1189        947       1266        693       1288
ENSG00000003096        550        315        557        171        519
ENSG00000003137        124         57        256         63         30
ENSG00000003147          0          0          0          1          1
ENSG00000003249         81         71        207         80        109
ENSG00000003393        769        723        791        540       1115
ENSG00000003400         98         59        133         72         58
ENSG00000003402       1424       2617       1742       2364       2342
ENSG00000003436       4373       4183       5794       3230       7344
ENSG00000003509        287        280        357        191        386
ENSG00000003756       2368       1748       2694       1327       2647
ENSG00000003987         17         25         25         29         20
ENSG00000003989         47         56         12          3         51
ENSG00000004059       1090       1306       1140        817       1334
ENSG00000004139         86         83        103         51        115
ENSG00000004142       1496       1545       1607        964       1754
ENSG00000004399       4077       4260       3651       1649       5387
ENSG00000004455       1207       1111       1485        767       1497
ENSG00000004468          3          1          0          0          3
ENSG00000004478        502        461        551        281        612
ENSG00000004487       1410        989       1492        727       1708
ENSG00000004534       1202       1015       1855        919       1721
ENSG00000004660         95         55         59         35         87
ENSG00000004700        940       1096       1192        766        949
ENSG00000004766        492        413        546        337        611
ENSG00000004776       3473       3078       2775       1621       2084
ENSG00000004777        131        112        134         56         91
ENSG00000004779        329        335        494        258        417
ENSG00000004799         81        782        130       1106        235
ENSG00000004809          0          0          0          0          0
ENSG00000004838         12         11         22          8         12
ENSG00000004846         23          3         70         11          8
ENSG00000004848          0          0          0          0          0
ENSG00000004864        143        117        131         88        227
ENSG00000004866        449        259        772        241        527
ENSG00000004897       1549       1339       1730       1107       1793
ENSG00000004939          0          0          0          0          0
ENSG00000004948          0          0          0          0          0
ENSG00000004961        446        330        531        287        666
ENSG00000004975       1366       1002       1069        516       1237
ENSG00000005001          0          0          0          0          0
ENSG00000005007       2158       2266       2436       1518       2341
ENSG00000005020        833        781        715        556        637
ENSG00000005022       1340       1059       1323        785       1294
ENSG00000005059        215        197        249        177        193
ENSG00000005073          1          0          1          0          1
ENSG00000005075        797        828       1010        529        980
ENSG00000005100        434        445        487        356        522
ENSG00000005102          1          0          0          0          3
ENSG00000005108          9          7          6          8          9
ENSG00000005156        229        143        242         93        347
ENSG00000005175        347        294        237        123        513
ENSG00000005187          4          6         12         10          9
ENSG00000005189         82         62         88         58         92
ENSG00000005194        413        410        557        352        537
ENSG00000005206        680        586        760        418        748
ENSG00000005238        805        627        850        396        989
ENSG00000005243       1132        928       1332        755        990
ENSG00000005249        220        242        281        317        291
ENSG00000005302        481        523        495        316        496
ENSG00000005339       2639       1917       3135       1491       3225
ENSG00000005379        186        152        122         87        171
ENSG00000005381          4         10          9          1          0
ENSG00000005421          0          0          0          0          1
ENSG00000005436        214        216        282        182        318
ENSG00000005448        229        206        270        152        234
ENSG00000005469        498        379        305        171        626
ENSG00000005471         64         18         60         17         21
ENSG00000005483       1679       1466       1698       1096       2159
ENSG00000005486        768        618       1110        564       1185
ENSG00000005513         10          2          5          0          5
ENSG00000005700       1069        824       1512        790       1335
ENSG00000005801        200        172        295        136        320
ENSG00000005810       2688       2018       2621       1535       2946
ENSG00000005812       1361       1380       1381       1300       1126
ENSG00000005844          1          0          2          0          1
ENSG00000005882        610        546        740        407        817
ENSG00000005884        708        655       1566       1114       1328
ENSG00000005889        679        593        771        465        857
ENSG00000005893       5102       4470       6219       3853       5653
ENSG00000005955       1329       1279       1772       1055       1705
ENSG00000005961          5         11         12          3          7
ENSG00000005981          0          0          0          0          0
ENSG00000006007       1941       1825       2481       1676       2858
ENSG00000006015        517        463        410        191        260
ENSG00000006016        132         95         98         82         79
ENSG00000006025        229        132        278         78        185
ENSG00000006042       2986       2393       3664       2077       3852
ENSG00000006047          0          1          1          0          1
ENSG00000006059          0          0          0          0          0
ENSG00000006062        272        224        274         79        287
ENSG00000006071          0          0          0          0          0
ENSG00000006074          0          0          0          0          0
ENSG00000006075          0          0          0          0          0
ENSG00000006114       1224        711       1310        560       1537
ENSG00000006116          0          0          0          0          0
ENSG00000006118        513        336        579        254        738
ENSG00000006125       7174       5362       7780       5110       8105
ENSG00000006128          0          4          1          0          0
ENSG00000006194        540        451        583        433        664
ENSG00000006210          5          6          2          3          3
ENSG00000006282       1747       1317       1334        715       1633
ENSG00000006283        113         45         40          5        157
ENSG00000006327        540        348        668        258        720
ENSG00000006377          0          0          0          0          0
ENSG00000006432          5          4          7          5         12
ENSG00000006451       1791        920       1143        544       1574
ENSG00000006453        141         99        207        108        195
ENSG00000006459        430        327        338        289        462
ENSG00000006468        214         94        207        120        171
ENSG00000006530        303        276        344        203        420
ENSG00000006534        875       1108       1391        856       1521
ENSG00000006555          0          0          0          0          0
ENSG00000006576        924        653       1538        678       1347
ENSG00000006606          3          4          7          1          7
ENSG00000006607        652        733        924        776        674
ENSG00000006611          0          0          0          0          0
ENSG00000006625        207        186        216        101        289
ENSG00000006634         98         70        104         48        113
ENSG00000006638         90         47        112         43         75
ENSG00000006652        889        823       1047        586       1581
ENSG00000006659          0          0          0          0          0
ENSG00000006695        166        150        221        130        209
ENSG00000006704        309        221        346        170        330
ENSG00000006712        991        866       1504        715       1575
ENSG00000006715       2054       1582       2681       1578       2825
ENSG00000006740         37         26         27         18         38
ENSG00000006744        928        935       1065        617       1090
ENSG00000006747          3          3          1          0          2
ENSG00000006756        391        295        488        278        541
ENSG00000006757        119        140        175         86        203
ENSG00000006788          4         35          0          1          5
ENSG00000006831       1070       1033       1187        851       1181
ENSG00000006837         17          6         13          7         17
ENSG00000007001          3          3          4          0          3
ENSG00000007038          1          0          5          2          0
ENSG00000007047        741        675        840        553        979
ENSG00000007062          1          0          1          0          0
ENSG00000007080        617        697        698        393        786
ENSG00000007129          0          0          0          0          0
ENSG00000007168       3191       2910       3808       2388       3809
ENSG00000007171          0          2          0          0          2
ENSG00000007174          0          1          1          0          2
ENSG00000007202       4196       3353       5237       2825       5104
ENSG00000007216          0          0          0          0          0
ENSG00000007237        404        114        309         42        277
ENSG00000007255        129        145        116        115        139
ENSG00000007264          0          0          0          0          0
ENSG00000007306          0          0          0          0          0
ENSG00000007312          1          2          0          4          5
ENSG00000007314          0          1          2          1          1
ENSG00000007341        138        110        154         77        189
ENSG00000007350          0          0          0          0          0
ENSG00000007372         32         35         27         22         22
ENSG00000007376        281        274        224        122        309
ENSG00000007384       1982       1878       1987       1001       1937
ENSG00000007392        770        591        820        415        836
ENSG00000007402         18         13         12         20         15
ENSG00000007516          5          8          7          5         12
ENSG00000007520        494        464        488        252        487
ENSG00000007541        731        621        682        369        641
ENSG00000007545        203        207        227        148        248
ENSG00000007866       1474       2063       1696       1375       1246
ENSG00000007908          0          0          0          0          0
ENSG00000007923        561        533        702        393        824
ENSG00000007933        761        785       2179       1583        224
ENSG00000007944        373        245        522        193        514
ENSG00000007952         10         11          8          9         12
ENSG00000007968          1          4          1          2          0
ENSG00000008018       1669       1479       1787       1096       1633
ENSG00000008056          8         24         25         15         15
ENSG00000008083        277        260        284        220        308
ENSG00000008086         98         90        128         37        142
ENSG00000008118          3          3          9          2          9
ENSG00000008128         32         23         24         10         14
ENSG00000008130       1276       1814       1413       1420       1445
ENSG00000008196          1          1          1          1          0
ENSG00000008197          0          0          0          0          0
ENSG00000008226          9          4          5          2          6
ENSG00000008256       1815       3053       3036       3707       2771
ENSG00000008277         17         14         23         14         21
ENSG00000008282       1874       1763       1958       1647       1894
ENSG00000008283        559        480        612        339        629
ENSG00000008294       2819       2278       3539       2009       3259
ENSG00000008300         62         81         87         49        124
ENSG00000008311        494        949        565        655        451
ENSG00000008323          7         12          4          3         11
ENSG00000008324        111        153         85        102        109
ENSG00000008382         81         66         88         49        110
ENSG00000008394       2722       2822       2967       1948       7202
ENSG00000008405        249        261        269        165        277
ENSG00000008438          0          6          1          1          1
ENSG00000008441      13653       9483      13436       6080      12077
ENSG00000008513       2057       1206       1752        588       2655
ENSG00000008516          3          1          3          0          6
ENSG00000008517        277        120        323         97         92
ENSG00000008710       4997       5334       5264       3282       4274
ENSG00000008735         13         21         18         13         18
ENSG00000008838       1228       1002       1320        685       1431
ENSG00000008853        429        487        510        442        513
ENSG00000008869        737        646        780        471        798
ENSG00000008952       4473       4375       5375       3611       5753
ENSG00000008988      12982      11687      13055       6973      11456
ENSG00000009307      14887      12833      19863      11612      19887
ENSG00000009335       2019       2042       2213       1518       2429
ENSG00000009413       4986       9573       5214       7251       5563
ENSG00000009694         20          7          2          2          2
ENSG00000009709          0          0          0          0          0
ENSG00000009724         38         28         66         24         42
ENSG00000009765          0          2          0          1          0
ENSG00000009780        153        209        153        165        147
ENSG00000009790         18         11         15          7         12
ENSG00000009830        425        418        440        295        508
ENSG00000009844        829        672       1049        545       1087
ENSG00000009950          2          9          1          1          0
ENSG00000009954       2800       2611       3397       1970       3813
ENSG00000010017       1300       1960       1559       1655       1705
ENSG00000010030         28         13         20          8         15
ENSG00000010072        169        141        202        125        212
ENSG00000010165        947        938       1152        605       1030
ENSG00000010219        200        157        246        110        256
ENSG00000010244       2085       1998       2170       1331       2616
ENSG00000010256       1630       1776       1661       1331       1973
ENSG00000010270        879        803        837        511        961
ENSG00000010278       3125       3522       3829       3645       2693
ENSG00000010282          0          0          0          0          0
ENSG00000010292       1331       1028       1365        823       1281
ENSG00000010295       1427       1228       1714        820        936
ENSG00000010310         11          5         29          6         23
ENSG00000010318         68         56         80         60         85
ENSG00000010319          1          0          2          0          0
ENSG00000010322       2635       1889       3298       1480       3737
ENSG00000010327          0          0          1          1          0
ENSG00000010361        188        178        236        132        150
ENSG00000010379          0          1          4          1          0
ENSG00000010404       1483       1306       2374       1593       2171
ENSG00000010438          5          5         10          5         17
ENSG00000010539        128         99        139         83        153
ENSG00000010610         31         23         95         49        133
ENSG00000010626        149        107        194        105        169
ENSG00000010671          0          0          0          0          1
ENSG00000010704        513        315        595        327        483
ENSG00000010803        758        686        864        523        966
ENSG00000010810       1689       1674       1655        933       2496
ENSG00000010818       1654       1096       1795        742       2004
ENSG00000010932         14         20         80         61          0
ENSG00000011007       1184       1093       1130        789       1249
ENSG00000011009        452        473        489        292        514
ENSG00000011021        697        581        629        382        667
ENSG00000011028      18210      13395      23978      10779      18026
ENSG00000011052          0          0          0          0          0
ENSG00000011083          0          0          1          1          1
ENSG00000011105       3067       2923       3305       2380       3330
ENSG00000011114       1278       1090       1233        806       1397
ENSG00000011132        186        200        220        115        223
ENSG00000011143        185        132        203         86        145
ENSG00000011198        597       1420        824       1035       1244
ENSG00000011201          1          0          1          0          0
ENSG00000011243        675        603        810        369        935
ENSG00000011258        421        279        412        225        487
ENSG00000011260        472        469        375        294        428
ENSG00000011275       1709       1488       1906       1069       2174
ENSG00000011295        399        370        437        331        454
ENSG00000011304       3594       3854       3158       2420       3609
ENSG00000011332         11          8         18          9         12
ENSG00000011347        182        100        161         59        233
ENSG00000011376        561        482        445        268        459
ENSG00000011405       1115       1271       1550       1100       1832
ENSG00000011422        389        349        502        240        340
ENSG00000011426        251        228        250        145        274
ENSG00000011451       1589       1667       1666        925       1689
ENSG00000011454       1872       1815       2408       2249       2322
ENSG00000011465     219586     191767     422752     214062     293318
ENSG00000011478        101        130        131        135        123
ENSG00000011485        789       1106        911        667       1018
ENSG00000011523        709        677       1001        557       1008
ENSG00000011566        880       1189       1295       1207       1359
ENSG00000011590          3          6          7          1          1
ENSG00000011600          0          1          4          3          0
ENSG00000011638        958        816        877        683        871
ENSG00000011677          0          1          0          0          0
ENSG00000012048        322         98        418         95        326
ENSG00000012061        812        747       1105        492       1038
ENSG00000012124          0          1          0          0          0
ENSG00000012171       1821        940       2266        654       1361
ENSG00000012174        713        607        812        516        805
ENSG00000012211        124        136        127         68        140
ENSG00000012223          0          0          0          1          4
ENSG00000012232       1145        983       1402        889       1597
ENSG00000012504          0          0          0          0          0
ENSG00000012660       2045       1814       2584       2229       2275
ENSG00000012779          0          2          0          0          0
ENSG00000012817       1094        988       1254        628       1392
ENSG00000012822       4637       5256       6763       4921       6378
ENSG00000012963        572        525        684        380        562
ENSG00000012983       1782       1400       2309       1231       2551
ENSG00000013016       2011       3335       1842       1018       1832
ENSG00000013275       1005        983       1002        660       1096
ENSG00000013288       3030       2465       4089       2353       4067
ENSG00000013293        268         23        435         56        558
ENSG00000013297       6494       1515       5298       1369       5198
ENSG00000013306       1011        963       1092        558       1323
ENSG00000013364       8611       7956       8539       5287       7726
ENSG00000013374       1036       1070       1483        951       1550
ENSG00000013375       1031        726       1277        541       1380
ENSG00000013392        243        153        301        162        329
ENSG00000013441       2512       2587       2403       2111       3280
ENSG00000013503        248        252        304        168        311
ENSG00000013523        358        299        451        190        486
ENSG00000013561        788        845        960        755        989
ENSG00000013563        140        110        212        146        255
ENSG00000013573        337        210        254         81        226
ENSG00000013583       1181       1174       1435       1240       1594
ENSG00000013588        531        409        920        538        868
ENSG00000013619        795       1112       1211        816       1314
ENSG00000013725          0          0          0          0          0
ENSG00000013810         75         88         98         45         58
ENSG00000014123        930        699        995        619       1123
ENSG00000014138        192        139        217         99        156
ENSG00000014164        585        486        588        296        532
ENSG00000014216       3263       3554       3997       2439       3454
ENSG00000014257         16         11         21          7         15
ENSG00000014641       1613       1303       1876       1058       1834
ENSG00000014824       1160        980       1561        997       1621
ENSG00000014914        590        350        814        396        672
ENSG00000014919        699        559        778        448        785
ENSG00000015133          5          9          4          7          5
ENSG00000015153        185        270        233        203        262
ENSG00000015171       2085       1840       2567       1466       2761
ENSG00000015285          6          5         10          1         10
ENSG00000015413          0          2          0          1          0
ENSG00000015475        274        261        364        214        533
ENSG00000015479       7206       5499       8268       4596       8997
ENSG00000015520         21          4         24          1         70
ENSG00000015532        716        608        760        416        792
ENSG00000015568       1045        858       1422        729       1817
ENSG00000015592          0          2          0          1          0
ENSG00000015676       1741       1509       1826       1186       1748
ENSG00000016082          0          0          0          0          0
ENSG00000016391        161         21        164         26         70
ENSG00000016402         17         10         12          3          5
ENSG00000016490          0          1          0          0          0
ENSG00000016602          1          0          0          0          0
ENSG00000016864       1544       1449       1854       1220       1483
ENSG00000017260       2832       2074       3156       1862       3269
ENSG00000017373          0          1          1          1          1
ENSG00000017427       1059        877       1364        688        498
ENSG00000017483        757        348        630        112        555
ENSG00000017621         20         11         26         11         22
ENSG00000017797       2893       3638       2933       2418       3462
ENSG00000018189       1123        809       1195        614       1474
ENSG00000018236         49         49         35         40         41
ENSG00000018280          8          3          7          3          3
ENSG00000018408       2883       2568       2659       1817       3208
ENSG00000018510        743        713        883        503        903
ENSG00000018607          0          0          0          0          0
ENSG00000018610        304        235        337        190        337
ENSG00000018625        334        176       2889        841        238
ENSG00000018699        245        209        285        194        324
ENSG00000018869         52         58         71         43         79
ENSG00000019102          1          0          4          7         16
ENSG00000019144       2786       3651       3236       1888       2973
ENSG00000019169          0          2          0          0          0
ENSG00000019186         70          3          9          0         12
ENSG00000019485        183        199        194        122        157
ENSG00000019505          0          0          0          0          0
ENSG00000019549       3302       5290       2847       1591       3859
ENSG00000019582         23         15        100         34         32
ENSG00000019991       1529        909       1319        405       2440
ENSG00000019995       1338       2505       1585       1850       2011
ENSG00000020129       1443        929       1280        469       1384
ENSG00000020181       9153       5457       9560       3956       9105
ENSG00000020219          0          0          0          0          1
ENSG00000020256        326        284        446        153        413
ENSG00000020426        161        132        238        125        232
ENSG00000020577       2102       3748       1923       2684       2036
ENSG00000020633        123        151         97         65          3
ENSG00000020922        325        279        389        239        378
ENSG00000021300         18          6         18         11         22
ENSG00000021355        536        660        627        512        577
ENSG00000021461          0          0          0          0          0
ENSG00000021488          2          2          1          0          3
ENSG00000021574        500        475        567        369        518
ENSG00000021645          8         20         42         63         12
ENSG00000021762       1433       1673       1192        771       1376
ENSG00000021776       1111       1014       1230        802       1310
ENSG00000021826        397        259        474        216        299
ENSG00000021852          0          0          0          0          0
ENSG00000022267       7354       8775      11436       8544       8584
ENSG00000022277       1404       1281       1676        955       1601
ENSG00000022355          0          0          0          0          0
ENSG00000022556          0          0          1          0          1
ENSG00000022567        134        130        151         97        165
ENSG00000022840       2599       2616       2910       2091       2820
ENSG00000022976        195        122        263        118        209
ENSG00000023041        636        662        749        480        767
ENSG00000023171         70         24         91         33        197
ENSG00000023191       5592       5383       6055       3227       3972
ENSG00000023228       1559       1458       1771       1108       1976
ENSG00000023287       2561       2374       2933       1990       3640
ENSG00000023318       1317       1231       1490       1038       1602
ENSG00000023330       1026        815       1155        522       1528
ENSG00000023445         62         77         46         32         44
ENSG00000023516       1901       1496       2119       1185       2318
ENSG00000023572         94        104         93         81         84
ENSG00000023608        136        196        234        232        238
ENSG00000023697        474        517        488        364        486
ENSG00000023734       1638       1972       2207       1551       2519
ENSG00000023839         18         21          9          9         14
ENSG00000023892          4          2          6          3         14
ENSG00000023902        636        732        630        497        837
ENSG00000023909        990       1611       1304       1842       1364
ENSG00000024048       1304       1128       1550        964       1454
ENSG00000024422      10940      11446      13005       7734      14671
ENSG00000024526         26         21         16          8         16
ENSG00000024862        206        229        291        185        256
ENSG00000025039          4         15          6          3          7
ENSG00000025156        307        213        315        146        330
ENSG00000025293       1601       1390       1668        937       1915
ENSG00000025423        232         69        637         56         89
ENSG00000025434        374        454        484        276        456
ENSG00000025708        110        280         87         82        114
ENSG00000025770        423        364        401        194        352
ENSG00000025772        832        555        939        386       1548
ENSG00000025796       2806       2298       4367       2452       4270
ENSG00000025800       1700       1614       2056       1402       2353
ENSG00000026025      32264      20759      37558      21944      39307
ENSG00000026036         62         41         75         16         33
ENSG00000026103       1013        863       1394        682       1390
ENSG00000026297        115         66        139         53        112
ENSG00000026508      19273      12357      25453      14886      24143
ENSG00000026559         24         18         10          2         23
ENSG00000026652        419        316        315        168        532
ENSG00000026751          0          0          0          1          0
ENSG00000026950       1051        472       1135        388       1166
ENSG00000027001        502        347        740        311        649
ENSG00000027075         19         40         62         48         78
ENSG00000027644          2          0          1          0          2
ENSG00000027697       1322       1566       1340       1211       1587
ENSG00000027847        492        381        570        241        511
ENSG00000027869          1          0          1          0          0
ENSG00000028116        155        171        207        133        227
ENSG00000028137        398        575        600        472        288
ENSG00000028203        991        847       1662        971       1360
ENSG00000028277         70         14         34          3        104
ENSG00000028310        525        481        703        357        692
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ENSG00000028839        437        364        514        245        661
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ENSG00000029363       3169       2519       4148       2247       3766
ENSG00000029364       1442       1008       1718        958       1705
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ENSG00000029725       1573       1401       1769       1045       1925
ENSG00000029993        518        369        892        362        831
ENSG00000030066        991        835        919        610       1054
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ENSG00000030304         24         46         31         15         24
ENSG00000030419        208        155        257        152        209
ENSG00000030582      10904       7964      13735       6999      13548
ENSG00000031003       1112        857       1312        746       1239
ENSG00000031081        364        174        425        147        599
ENSG00000031544          2          1          3          6          5
ENSG00000031691         56         54         83         52        115
ENSG00000031698       3342       2305       3980       1564       3815
ENSG00000031823       1780       1238       2312        777       1884
ENSG00000032219        619        566        804        404        777
ENSG00000032389        238        194        295        114        225
ENSG00000032444       1140       1097       1529        927       1440
ENSG00000032742        263        144        354        123        321
ENSG00000033011        304        275        363        202        337
ENSG00000033030        370        395        413        249        444
ENSG00000033050       1075       1342       1243        880       1599
ENSG00000033100       2131       1719       2559       1515       2747
ENSG00000033122          6          3         12          3          6
ENSG00000033170       1519       1435       2076       1014       2294
ENSG00000033178        957        629       1067        586       1170
ENSG00000033327       1119       1159       1267       1073       1376
ENSG00000033627        680        964        781        656        723
ENSG00000033800        610        512        822        451        727
ENSG00000033867       2642       1247       3493       1206       3405
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ENSG00000034063        110         73        116         38        111
ENSG00000034152        790       1203        897        944        659
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ENSG00000034510      10829      10179      16055       7516      16784
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ENSG00000034677        761        790        829        566        710
ENSG00000034693        290        191        355        164        433
ENSG00000034713       1316       1377       1415       1165       1397
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ENSG00000035141        335        307        373        249        373
ENSG00000035403      11418      16360      17309      15613      10103
ENSG00000035499         27         13         12          2         18
ENSG00000035664        174        491        520        792        161
ENSG00000035681       1170        833       1287        637       1396
ENSG00000035687        756        626        857        552        989
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ENSG00000035862      36898      31612      48710      35384      50093
ENSG00000035928       1120        906       1143        634       1313
ENSG00000036054       1296       1211       1181        855       1451
ENSG00000036257       1634       1441       2001       1189       2351
ENSG00000036448         27         23         14          4         69
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ENSG00000036549        852        680        964        599       1045
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ENSG00000037637        578        568        640        502        638
ENSG00000037749        766        736        888        663        878
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ENSG00000038002        823        464        738        404        504
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ENSG00000038219       2340       1842       2723       1370       3114
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ENSG00000038295         12          5         37          9          7
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ENSG00000038382       6353       5208       7611       3043       6941
ENSG00000038427       9624       6485      11227       3855      10844
ENSG00000038532        667        517        742        381        909
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ENSG00000039523       1138       1257       1036        728       1101
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ENSG00000039560       3717       4005       4846       3934       5125
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ENSG00000039650        437        303        391        153        386
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ENSG00000040341        635        448        800        432        760
ENSG00000040487        219        252        219        155        271
ENSG00000040531        462        385        567        306        615
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ENSG00000040731        107         42        108         15         35
ENSG00000040933        751        571        835        519        764
ENSG00000041353         37         14         17          5        357
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ENSG00000041802        438        470        590        348        640
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ENSG00000041982       3318       1037       7317       2925       2468
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ENSG00000042062       1600       1808       1282        656       2182
ENSG00000042088        207        137        235        107        276
ENSG00000042286        457        641        562        467        514
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ENSG00000042317        233        152        249        138        283
ENSG00000042429        400        362        414        302        450
ENSG00000042445       1289       1137       1676        863       1534
ENSG00000042493        861        866       1124        613        851
ENSG00000042753       1102       1173       1406        839       1207
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ENSG00000042980          3          4         12          3         13
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ENSG00000052795        474        469        501        336        704
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ENSG00000053747        927       1358        513        951       1378
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ENSG00000067842          3          0          4          0          7
ENSG00000067900       1968       2491       2437       2302       2680
ENSG00000067955        557        578        476        506        575
ENSG00000067992         64         47         81         47         50
ENSG00000068001        460        340        541        254        567
ENSG00000068024        505        427        513        296        635
ENSG00000068028        709        813        695        573        580
ENSG00000068078         17         22          8          4          3
ENSG00000068079        412        389        446        280        382
ENSG00000068097        387        337        556        237        456
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ENSG00000068137        463        481        497        200        405
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ENSG00000068323       2117       1919       2589       1425       2909
ENSG00000068354        292        273        336        167        336
ENSG00000068366       3811       2557       3565       1721       7062
ENSG00000068383        540       1140        952       1581        561
ENSG00000068394        342        288        373        246        409
ENSG00000068400        559        509        731        404        785
ENSG00000068438        450        355        450        224        478
ENSG00000068489        103         64         79         49        111
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ENSG00000068654       1045        938       1353        873       1233
ENSG00000068697       8932       6885       9481       4746      11514
ENSG00000068724        943        746       1282        674        903
ENSG00000068745        944        630       1148        532        970
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ENSG00000068784        349        221        383        131        394
ENSG00000068793       2789       2489       3333       2229       3345
ENSG00000068796        595        501        712        322        775
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ENSG00000068878       1400       1439       1576       1137       1845
ENSG00000068885        653        441        769        445        781
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ENSG00000068912       1619       1613       2297       1510       2075
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ENSG00000069399        403        335        570        165        552
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ENSG00000069431        435        769        688        863        438
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ENSG00000069667        501        578        429        308        499
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ENSG00000069702       3761       4071       4226       2816       4863
ENSG00000069712        155        117        231        156        191
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ENSG00000069849       1351       1523       1993       1315       2254
ENSG00000069869        998       1169       1070        631       1382
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ENSG00000069956       1032        784       1039        560       1178
ENSG00000069966        511        429        567        300        502
ENSG00000069974        571        775        706        378        846
ENSG00000069998        391        538        337        249        414
ENSG00000070010        652        688        585        397        544
ENSG00000070018       2170       1243       2385       1055       1986
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ENSG00000070047        986        963        946        551       1018
ENSG00000070061       1080        896       1072        601       1034
ENSG00000070081       1699       1029       2349        981       2293
ENSG00000070087       2390       1666       2847       1415       2746
ENSG00000070159         49         67         37         31        128
ENSG00000070182          8          4         13          3          7
ENSG00000070190          1          2          1          3          0
ENSG00000070193        323        102         71         19        222
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ENSG00000070269        458        293        521        237        440
ENSG00000070366       1787       1343       2181       1018       2049
ENSG00000070367       1396       1197       1494        840       1581
ENSG00000070371        170        198        211        197        223
ENSG00000070388          1          9          3          8          1
ENSG00000070404       1130       4307       1064       1957        703
ENSG00000070413       2793       2156       2799       1620       2337
ENSG00000070423        299        351        286        182        339
ENSG00000070444        670        683        607        356        729
ENSG00000070476        353        384        397        292        349
ENSG00000070495        247        354        255        174        355
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ENSG00000070785        270        264        368        192        352
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ENSG00000070814        746        703        803        329       1081
ENSG00000070831       3556       3190       4081       2661       4259
ENSG00000070882       1510        778       2067        445       2004
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ENSG00000070950        176        142        206        167        195
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ENSG00000071073         12         11          2          2          3
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ENSG00000071189       1192        995       1363        728       1575
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ENSG00000071246        238        181        219        115        229
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ENSG00000071462        724        628        819        402        901
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ENSG00000071575        389        160        497        237        458
ENSG00000071626       1021        936       1084        732       1148
ENSG00000071655        944        762        923        484        941
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ENSG00000071889        703        713        816        477        738
ENSG00000071894       1846       1655       1446        731       1811
ENSG00000071909         26         31         28          3          8
ENSG00000071967      22573      21775      33051      23254      38597
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ENSG00000072134        640        596        642        517        752
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ENSG00000072163        249        512        732        815        291
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ENSG00000072401        615        528        554        408        611
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ENSG00000072422        697        693        829        457        898
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ENSG00000072506        532        536        517        316        467
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ENSG00000073598          2          3          3          1          4
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ENSG00000073614       1623       1269       1817       1078       1804
ENSG00000073670         52         20         41         17         54
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ENSG00000074054       1510       1541       1704       1129       2020
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ENSG00000079102       1223        843       1251        497       1092
ENSG00000079112          4          2          8          5          4
ENSG00000079134        380        267        404        212        467
ENSG00000079150        913        679        826        355        760
ENSG00000079156         26         18         42         10         38
ENSG00000079215        105        120         62         12        109
ENSG00000079246       4924       4600       5683       3524       6431
ENSG00000079257       3791       1626       3147        956       1418
ENSG00000079263         26         15         29         18         29
ENSG00000079277        435        357        550        346        523
ENSG00000079308       7483       4855       7543       3406       8152
ENSG00000079313        283        294        352        242        322
ENSG00000079332       3297       3311       3466       2544       3912
ENSG00000079335         59         39         71         29         96
ENSG00000079337        113         80         89         41         94
ENSG00000079385          0          2          7          5          3
ENSG00000079387        351        329        421        305        504
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ENSG00000079432       2467       1512       2612        983       2700
ENSG00000079435         19         34         36         30         27
ENSG00000079459        998        887       1185        690       1068
ENSG00000079462         84         38         92         25         90
ENSG00000079482        242        212        249        147        247
ENSG00000079557          0          0          0          0          0
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ENSG00000079739       1124       1000       1694       1008       1358
ENSG00000079785       1951       1775       2140       1313       2157
ENSG00000079805       2236       2072       2656       1517       2649
ENSG00000079819       7012       5901      10164       3838       9627
ENSG00000079841         13         13         77         71         18
ENSG00000079931       7133       3788       6575       3664       6017
ENSG00000079950       1262       1243       1274       1130       1194
ENSG00000079974        559        467        733        353        705
ENSG00000079999       1741       1567       1622       1085       1767
ENSG00000080007         45         25         16          7         17
ENSG00000080031         29         10         88         17         15
ENSG00000080166          5          4          5          3          9
ENSG00000080189        686        608        789        460        779
ENSG00000080200        646        405        735        237        729
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ENSG00000080371       1024        959       1149        881       1175
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ENSG00000080503       3293       2859       4282       2712       2946
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ENSG00000080546        685        531        743        356        759
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ENSG00000080603       2829       2543       3248       1574       3431
ENSG00000080608        354        419        534        311        578
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ENSG00000080819        542        535        516        287        561
ENSG00000080822        743        915        681        614        820
ENSG00000080823        131         76        179         40        167
ENSG00000080824      15757      10887      21118       8492      24822
ENSG00000080839        154        146        165        101        108
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ENSG00000080986         43         52         39         29         28
ENSG00000081014        495        387        673        335        571
ENSG00000081019        369        315        353        251        400
ENSG00000081026        339        239        376        164        414
ENSG00000081041          1          1          2          0          7
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ENSG00000081052         59        192        156        324         67
ENSG00000081059         56         37         57         29         57
ENSG00000081087       1097       1104       1063       1084       1089
ENSG00000081138          0          0          0          0          0
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ENSG00000081154       2959       2325       3178       1930       2937
ENSG00000081177        426        400        519        312        358
ENSG00000081181          8         18          8          6          8
ENSG00000081189        142        103        156         45        147
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ENSG00000081377       1529       2314       1948       2302       1820
ENSG00000081386        306        200        411        181        381
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ENSG00000081721        261        170        291        112        275
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ENSG00000081791       1140        851       1213        626       1213
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ENSG00000081853        122        110        196        114        440
ENSG00000081870        201        250        253        173        255
ENSG00000081913        185        154        317        154        240
ENSG00000081923       1181       1015       1607       1038       1171
ENSG00000081985          2          3          2          4          0
ENSG00000082014        632        591        772        458        797
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ENSG00000082153       4939       5669       6261       4332       6234
ENSG00000082175          5          6         11          3          1
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ENSG00000082212        467        381        541        332        538
ENSG00000082213        325        344        497        367        507
ENSG00000082258        656        581        771        493        757
ENSG00000082269        229        125        216        145        276
ENSG00000082293          0          1          0          0          4
ENSG00000082397       1002        778        278        111        204
ENSG00000082438        726        432       1123        599        886
ENSG00000082458        531        243        511        179        519
ENSG00000082482         48         18         45         16         64
ENSG00000082497         13          5          7          2         27
ENSG00000082512        365        449        492        334        407
ENSG00000082515        247        233        253        174        248
ENSG00000082516        437        432        434        344        544
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ENSG00000082641       8455       8661      12405       8512      10763
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ENSG00000082781       6702       5470       8600       4647       8420
ENSG00000082805       2521       2079       1984       1206       2289
ENSG00000082898       2525       2176       2882       1462       3190
ENSG00000082929          1          1          1          1          0
ENSG00000082996        871        874        922        816        939
ENSG00000083067          6         15         19         10         39
ENSG00000083093        199        139        232        109        259
ENSG00000083097        535        316        641        189        674
ENSG00000083099        512        399        675        345        648
ENSG00000083123        346        324        373        322        282
ENSG00000083168       1428       1080       1576        671       1639
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ENSG00000083290        842       1674       1152       1592       1048
ENSG00000083307          0          0          0          0          0
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ENSG00000083444       6546       4382       8088       4250       7100
ENSG00000083454          3          5          7          7          6
ENSG00000083457        264        277        258        211        215
ENSG00000083520        886        927       1161        762       1132
ENSG00000083535        315        262        382        246        396
ENSG00000083544        274        202        271        163        313
ENSG00000083622          0          0          0          0          0
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ENSG00000083720        615        811        911        934        819
ENSG00000083750        438        415        498        372        569
ENSG00000083782          3          0          0          0          4
ENSG00000083799       1179        863       1445        751       1393
ENSG00000083807         69         72         86         26         77
ENSG00000083812        210        171        232        115        221
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ENSG00000083817         91         69        130         62        152
ENSG00000083828         74         39         56         34         63
ENSG00000083838        138         98        143         88        146
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ENSG00000083845      10279       9963      10268       4659       8786
ENSG00000083857       8903       4948      10238       3860      12799
ENSG00000083896       1172        931       1391        781       1496
ENSG00000083937        653        649        926        631        978
ENSG00000084070        534        464        449        250        729
ENSG00000084072        475        415        680        377        559
ENSG00000084073       1829       1758       2131       1475       1894
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ENSG00000084092        622        483        601        318        706
ENSG00000084093        866        731       1050        710       1002
ENSG00000084110          0          5          3          2          0
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ENSG00000084207       4175       3581       4232       1976       3864
ENSG00000084234      20223      19044      30837      19112      33614
ENSG00000084444        248        247        245        219        221
ENSG00000084453          0          0          0          0          1
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ENSG00000084623       3017       2673       3081       1758       2962
ENSG00000084628          4          2          6          1          2
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ENSG00000084652       3050       3554       3999       2870       4399
ENSG00000084674         69        155        267        283         30
ENSG00000084676       1302       1116       1326        827       1379
ENSG00000084693        620        429        629        371        812
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ENSG00000084731        765        582        751        416        699
ENSG00000084733       2707       2235       2837       1760       2823
ENSG00000084734          5          8          5          1          3
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ENSG00000085063       9584       8822      12261       8087      13513
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ENSG00000085185        479        510        496        312        483
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ENSG00000085231        566        689        774        561        965
ENSG00000085265          0          0          0          0          0
ENSG00000085274        276        228        318        148        295
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ENSG00000085365       1141        853       1255        779       1230
ENSG00000085377        512        672        585        507        570
ENSG00000085382        363        264        330        221        395
ENSG00000085415        257        348        291        257        263
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ENSG00000085449       1640       1569       2343       1214       1931
ENSG00000085465         37         66         51         40         60
ENSG00000085491        830        765        819        642        924
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ENSG00000085721        647        669        770        573        940
ENSG00000085733       9594       8468      10990       6521      11654
ENSG00000085741          1          2          9          2          6
ENSG00000085760        515        450        640        370        639
ENSG00000085788        944        802       1441        844       1135
ENSG00000085831          4          8         16          6         19
ENSG00000085832       1888       1857       2388       1699       2117
ENSG00000085840          7          9          7          4         11
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ENSG00000085872        491        423        506        299        566
ENSG00000085978        473        537        607        425        687
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ENSG00000085998        949       1000       1326        824       1432
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ENSG00000086015       1838       1325       2592       1080       2346
ENSG00000086061       3832       3391       4703       2217       5243
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ENSG00000086065       1247       1100       1602       1017       1775
ENSG00000086102       1174        864       1376        601       1483
ENSG00000086159          0          3          2          1          0
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ENSG00000086200        472        377        553        283        503
ENSG00000086205          0          1          1          1          0
ENSG00000086232       1970       1829       2370       1438       2463
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ENSG00000086289        766        774       1984       1266       1003
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ENSG00000087077       2318       1775       2110        874       2056
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ENSG00000090520        801        688        968        576       1081
ENSG00000090530         77         46        170         80        136
ENSG00000090534         21         21         39         20         15
ENSG00000090539        205        224        419        187        218
ENSG00000090554          4          4          2          4          4
ENSG00000090565       1498       1720       1861       1504       2144
ENSG00000090581       1260        946       1413        642       1479
ENSG00000090612        287        213        458        213        480
ENSG00000090615       2427       2355       2456       1362       2514
ENSG00000090621       4169       3957       4140       2284       3126
ENSG00000090659          0          0          0          0          0
ENSG00000090661        381        251        175         84         45
ENSG00000090674        491        519        453        342        595
ENSG00000090686       1556       1672       1964       1168       2381
ENSG00000090776        780        414        924        272        485
ENSG00000090857       1227        973        810        448        973
ENSG00000090861       3182       2079       3968       1621       3744
ENSG00000090863       5427       4076       6802       3341       5404
ENSG00000090889         40         24         36         26         31
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ENSG00000090920         30         23         27         16         62
ENSG00000090924        830        835       1110        587       1322
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ENSG00000090971        383        341        290        189        300
ENSG00000090975        558        591        534        422        393
ENSG00000090989       1550       1286       1636        988       1673
ENSG00000091009        746        638        807        447        805
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ENSG00000091039       4041       3326       7276       3631       4419
ENSG00000091073        201        178        210        117        203
ENSG00000091106          3          4         13          9          8
ENSG00000091127        137        180        127        106        200
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ENSG00000091129        479        381        106         67         26
ENSG00000091136      20473      36444      27522      23536      23098
ENSG00000091137         11          8          6          7         10
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ENSG00000091140        845        755       1025        621        982
ENSG00000091157        464        385        557        304        577
ENSG00000091164       1418       1021       1592        809       1580
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ENSG00000091262        136         59        207         53        224
ENSG00000091317       1451       1781       1827       1654       1867
ENSG00000091409        113         95        429        401        312
ENSG00000091428         58         27         43          9         65
ENSG00000091436       4849       4012       4794       2621       5759
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ENSG00000091483        851        837        821        646       1117
ENSG00000091490       1481        693       2455        965       1995
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ENSG00000091527       3377       4918       4509       4454       4544
ENSG00000091536         48         48         69         20         43
ENSG00000091542       1388       1230       1718        947       1627
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ENSG00000091640        749        847       1044        632        779
ENSG00000091651         44         25         55         23         53
ENSG00000091656        862        511       1101        413       1116
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ENSG00000091732        213        193        287        154        264
ENSG00000091831         43         18         76         13         27
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ENSG00000091986     105505      96830     202413     110598      68921
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ENSG00000092010       1522       1355       1824        998       1791
ENSG00000092020        270        255        343        252        409
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ENSG00000092094        329        236        368        163        400
ENSG00000092096        507        383        391        179        485
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ENSG00000092108       1045        913       1347        748       1356
ENSG00000092140        312        296        330        240        348
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ENSG00000092199       4622       4782       5928       3542       6152
ENSG00000092200          4          5          4          2          7
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ENSG00000092208         91         67         93         65         70
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ENSG00000092330        823        628        961        495        853
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ENSG00000092439       1632       1627       2023       1310       2091
ENSG00000092445        546        312        492        242        554
ENSG00000092470        107         87        102         52        124
ENSG00000092529          9         19         21          6         11
ENSG00000092531        666        592        898        552        929
ENSG00000092607          2          0          5          4          3
ENSG00000092621       1851        764       2622        524       1279
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ENSG00000092820       1355       1504       2272       1164       1555
ENSG00000092841       5275       7624       8659       7053       6893
ENSG00000092847       1214        817       1155        623       1187
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ENSG00000092931        367        277        456        253        369
ENSG00000092964       4275       2439       5235       2420       4450
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ENSG00000093009         20         11          4          3         13
ENSG00000093010       2038       2268       2769       1517       2743
ENSG00000093072        919        544        717        363        864
ENSG00000093100          5          2          4          0          2
ENSG00000093134          7          3          5          0          6
ENSG00000093144       1206       1908       1233       1334       1551
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ENSG00000093183       1108       1464       1160       1132       1206
ENSG00000093217         85         42        101         21         94
ENSG00000094631        573        475        567        276        603
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ENSG00000094880        621        422        771        455        678
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ENSG00000094975        805        752        960        518        990
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ENSG00000095015        326        224        485        201        288
ENSG00000095059        501        467        523        310        511
ENSG00000095066        245        181        310        118        256
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ENSG00000095397        147         85        135         38        187
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ENSG00000095539        105        100        138         75        150
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ENSG00000095574        365        269        412        275        388
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ENSG00000095752         35         31         34         28        101
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ENSG00000095794        256        241        284        157        333
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ENSG00000096070       1026        834       1031        658       1307
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ENSG00000096433       1758       1585       3013       1575       2163
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ENSG00000096696         19         11         44         54        300
ENSG00000096717        529        456        534        396        568
ENSG00000096746       1471       1391       1737       1014       1443
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ENSG00000096968        553        918        556        642        621
ENSG00000096996          2          0          0          0          2
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ENSG00000097046         66         51         88         37         73
ENSG00000097096         87        247        159        159        112
ENSG00000099139        425        207        592        221        551
ENSG00000099194       2018        308       1615        190       1334
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ENSG00000099204        445        942        784       1008        418
ENSG00000099219        511        484        617        528        657
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ENSG00000099250       6214       4820       7254       3783       5815
ENSG00000099251         54         28         31         19         51
ENSG00000099256        441        330        468        220        507
ENSG00000099260         94         54        183         33        172
ENSG00000099282          1          0          0          0          1
ENSG00000099284        566        483        438        181        510
ENSG00000099290       4836       5912       7295       4625       7401
ENSG00000099308        396        370        442        297        312
ENSG00000099326        362        270        434        172        417
ENSG00000099330        137        168        208        136        203
ENSG00000099331       2731       2149       2582       1180       2906
ENSG00000099337         84        321        199        666        170
ENSG00000099338          9          4          7          9          4
ENSG00000099341       1616       1763       2052       1380       1992
ENSG00000099364        330        327        276        169        332
ENSG00000099365        102         54        116         46        123
ENSG00000099377        341        298        247        162        226
ENSG00000099381        579        540        626        328        689
ENSG00000099385        307        258        270        172        344
ENSG00000099399          0          0          0          0          0
ENSG00000099617          0          0          1          0          1
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ENSG00000099624        556        510        665        334        674
ENSG00000099625         79         71         61         43         87
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ENSG00000099769          2          0          4          1          2
ENSG00000099783       3410       3287       2836       1830       2631
ENSG00000099785        362        351        447        396        372
ENSG00000099795        602        589        821        312        682
ENSG00000099797        620        617        721        376        723
ENSG00000099800        442        514        427        245        449
ENSG00000099804        589        602        690        390        862
ENSG00000099810        386        349        379        286        379
ENSG00000099812          3          5          1          1          2
ENSG00000099814        949        840        923        442       1022
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ENSG00000099821        494        513        427        284        541
ENSG00000099822         25         40         41         28         46
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ENSG00000099849         23         35         42         50         19
ENSG00000099860        197        540        299        308        218
ENSG00000099864       1839       1514       3092       1803        788
ENSG00000099866          9          9         11          7          6
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ENSG00000099875       1456       1799       1797       1295       1566
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ENSG00000099899        467        389        454        221        470
ENSG00000099901        564        515        643        313        672
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ENSG00000099910        523        413        549        266        558
ENSG00000099917       1860       1697       2154       1165       1992
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ENSG00000099940        838        673       1008        494        941
ENSG00000099942       1611       1293       1570        907       1578
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ENSG00000099953        234        133        153         63        248
ENSG00000099954          1          0          0          0          1
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ENSG00000099977        250        283        295        171        241
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ENSG00000099994          7         11         66         70        140
ENSG00000099995       1968       1934       2060       1487       2111
ENSG00000099998         30        145        325        689        249
ENSG00000099999        269        266        317        192        299
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ENSG00000100012          0          0          0          0          0
ENSG00000100014        718        819        970        809        854
ENSG00000100023        857        683       1121        466        917
ENSG00000100024          4          0          1         13          2
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ENSG00000100028        785        664       1020        483       1009
ENSG00000100029       1055       1097       1263        719       1419
ENSG00000100030       3179       2664       3691       2233       3414
ENSG00000100031         41         41         79         33         36
ENSG00000100033          4        146          7         88          3
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ENSG00000100083        840        706        821        414        834
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ENSG00000100099        703        495        814        354        898
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ENSG00000100216        815        752        820        459        935
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ENSG00000100242       1074       3645       1206       2453        778
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ENSG00000100281        651        564        696        429        739
ENSG00000100284        771        828       1166        660       1307
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ENSG00000100296        497        530       1106        662        661
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ENSG00000100417        567        544        581        388        585
ENSG00000100418        581        581        635        409        738
ENSG00000100422       1663       1325       1607       1065       1769
ENSG00000100425        777        652        814        407        876
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ENSG00000103064        430       1037        522        775        523
ENSG00000103066        575        553        817        668        700
ENSG00000103067          0          0          1          1          4
ENSG00000103089          0          0          0          0          0
ENSG00000103091        755        608        814        436        776
ENSG00000103111        841        938        988        625        904
ENSG00000103121        117        111        103         93        150
ENSG00000103126        540        528        480        318        579
ENSG00000103145       1054        746       1175        489        856
ENSG00000103148        705        608       1058        539        837
ENSG00000103150         98        177        108        128        138
ENSG00000103152        569        553        678        287        563
ENSG00000103154          0          4          3          1          1
ENSG00000103160        474        368        467        251        572
ENSG00000103168        599        606        710        340        519
ENSG00000103174        399        343        498        255        421
ENSG00000103175         75        225        241        389         97
ENSG00000103184        106         96        123        111         48
ENSG00000103187       1786       2233       2221       1518       2290
ENSG00000103194        890        842        886        667       1047
ENSG00000103196        780       5764       1167       4211        887
ENSG00000103197       2362       1904       2376       1167       2666
ENSG00000103199        307        266        351        216        342
ENSG00000103200          0          0          0          0          0
ENSG00000103202       1590       1426       1939        863       2220
ENSG00000103222       6228       4589       6411       2742       7477
ENSG00000103226       3888       3402       5384       2973       4922
ENSG00000103227        250        290        294        188        360
ENSG00000103241       1582       1748       1646        983       2266
ENSG00000103245        271        242        241        137        238
ENSG00000103248        383        213        384        158        414
ENSG00000103249       1421       1128       1518        796       1624
ENSG00000103253         79        109         73         35         69
ENSG00000103254        112        115        103         56         74
ENSG00000103257        502        289        761         99        651
ENSG00000103260        343        390        227        132        324
ENSG00000103264       1016        990       1218        743       1117
ENSG00000103266        445        432        475        284        508
ENSG00000103269         50         37         47         34         35
ENSG00000103274        102         80         88         38        114
ENSG00000103275       1714       1486       1525        960       1597
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ENSG00000103316          9          6         11          4         39
ENSG00000103319       1111       1365       1098        723        832
ENSG00000103326        531        549        456        279        502
ENSG00000103335       2354       1970       3618       1957       3162
ENSG00000103342       2223       2307       2452       1837       2642
ENSG00000103343        134        114        190        107        201
ENSG00000103351        375        293        594        273        811
ENSG00000103353       2599       1812       2554       1218       2587
ENSG00000103355          0          0          0          0          0
ENSG00000103356        329        279        403        174        466
ENSG00000103363       1861       1747       1935       1033       1908
ENSG00000103365       1552       1034       1535        661       1339
ENSG00000103375          0          2          1          0          0
ENSG00000103381        449        660        543        595        633
ENSG00000103404        208        301        234        186        232
ENSG00000103415        508        510        553        332        540
ENSG00000103423        727        629        790        417        837
ENSG00000103426          0          0          0          0          0
ENSG00000103429       1158       1054       1356        872       1417
ENSG00000103449         23         23          3          5        107
ENSG00000103460          0          0          0          0          0
ENSG00000103472         94        101        143        101        137
ENSG00000103479       2235       2345       2322       1725       2320
ENSG00000103485       1360        487       1518        408       1310
ENSG00000103489        905        705       1198        465        840
ENSG00000103490        113        138         91         54        111
ENSG00000103494        270        210        319        155        393
ENSG00000103495        176        161        188         80        198
ENSG00000103496        688        652        739        355        798
ENSG00000103502       2566       3986       2609       2726       2991
ENSG00000103507        737        655        928        447       1056
ENSG00000103510        492        432        537        313        520
ENSG00000103512       4836       4232       5926       3168       6639
ENSG00000103522          2          0          1          1          1
ENSG00000103528          1          0          3          1          0
ENSG00000103534          0          2          3          1          7
ENSG00000103540        420        291        485        217        466
ENSG00000103544       1715       1561       1881       1144       1831
ENSG00000103546          0          0          1          0          0
ENSG00000103549       1735       1661       1842        944       2068
ENSG00000103550        132        102        124         96        134
ENSG00000103569          0          0          0          0          0
ENSG00000103591        680        575        987        509        978
ENSG00000103599         28         32         50         18         40
ENSG00000103642        393        450        363        326        736
ENSG00000103647        850        279        841        203        775
ENSG00000103653        504        461        573        298        712
ENSG00000103657       2055       1637       2099       1220       2225
ENSG00000103671        366        328        490        310        366
ENSG00000103707        162        202        237        171        262
ENSG00000103710       1820        979       1340        391       1843
ENSG00000103723         69         88         46         14         30
ENSG00000103740          3          1          3          1          0
ENSG00000103742        655        134        327         39       1303
ENSG00000103769       1755       1639       2148       1364       2341
ENSG00000103811        935        832       1316       1067        539
ENSG00000103832          4          0          4          1          7
ENSG00000103852        390        306        574        305        553
ENSG00000103855       3876       2696       3406       1655       3220
ENSG00000103876        429        328        427        187        562
ENSG00000103888      40294      50650     158457     142739      62722
ENSG00000103932        554        438        504        289        606
ENSG00000103942         82         44         87         38         49
ENSG00000103966        508        599        570        389        547
ENSG00000103978        639        692        752        613        750
ENSG00000103994       8765       8362      11487       8746      10646
ENSG00000103995        117         72        137         64        178
ENSG00000104043        665        407       1055        503       1127
ENSG00000104044          0          0          0          1          0
ENSG00000104047       1519       1042       1550        700       1665
ENSG00000104055          1          1          8          1          3
ENSG00000104059          4          4          5          2          5
ENSG00000104064        260        295        319        157        411
ENSG00000104067       2869       2662       3290       2522       3682
ENSG00000104081        342        140        229        111        215
ENSG00000104093        651        507        907        308        826
ENSG00000104112          0          0          0          0          0
ENSG00000104129         98         72        103         57        100
ENSG00000104131        542        562        593        418        766
ENSG00000104133       1927       1555       2028       1050       2072
ENSG00000104140          1          0          0          2          1
ENSG00000104142        894       1074        826        634        850
ENSG00000104147          5          3          8          6         10
ENSG00000104154        357        367        398        323        375
ENSG00000104164       1627       1413       1685       1072       1816
ENSG00000104177        136        116        236        137        187
ENSG00000104205         58         76         85         80         87
ENSG00000104213        193        225        305        219        393
ENSG00000104218        366        298        443        205        581
ENSG00000104219       1213       1077       1556       1332       1123
ENSG00000104221        121         99        193         94        141
ENSG00000104228        385        406        432        304        395
ENSG00000104231        313        221        365        203        341
ENSG00000104237          0          0          0          0          0
ENSG00000104267          0          2          0          0          0
ENSG00000104290          7          8          4          2          5
ENSG00000104299        250        209        290        167        268
ENSG00000104312        309        229        311        147        399
ENSG00000104313        137         76        120         39        152
ENSG00000104320        826        589        962        424       1081
ENSG00000104321        752        261        217         69       2245
ENSG00000104324       1383       1040       1470        946       1867
ENSG00000104325        835        776       1049        607       1224
ENSG00000104327          3          4          8          5          7
ENSG00000104331       2389       2373       2839       2145       2503
ENSG00000104332       4587       3910      14794      14657      10893
ENSG00000104341       1452       1040       1368        834       1531
ENSG00000104343        303        322        373        354        366
ENSG00000104356        260        199        245        110        205
ENSG00000104361       1111        852       1649        797       1978
ENSG00000104365        930        910       1071        730       1141
ENSG00000104368        943        510        888        462        949
ENSG00000104369          0          0          0          0          0
ENSG00000104371          0          0          0          0          0
ENSG00000104375        702        568        730        458        858
ENSG00000104381        172        142        184         84         89
ENSG00000104388       2518       2640       2868       2518       2739
ENSG00000104408       5895       5104       6523       3470       6720
ENSG00000104412        551        466        642        384        686
ENSG00000104413          0          0          0          0          0
ENSG00000104415        629        276        571        107        565
ENSG00000104419       3248       2618       3552       1805       4116
ENSG00000104427        286        230        284        191        383
ENSG00000104432         20         18         15         11         23
ENSG00000104435          0          2          4          0          1
ENSG00000104442        603        451        640        407        768
ENSG00000104447        460        354        506        236        542
ENSG00000104450         50         45         30         25         51
ENSG00000104472        484        511        644        480        583
ENSG00000104490         15         13         68         19         16
ENSG00000104497        196        168        155        116        265
ENSG00000104499          0          0          0          0          0
ENSG00000104517       3730       3244       4101       2502       4713
ENSG00000104518        784        676        717        349        648
ENSG00000104522        569        458        536        258        553
ENSG00000104524        120        129        117         73        126
ENSG00000104529       3147       2859       3361       1463       2828
ENSG00000104537          0          5          0          2          1
ENSG00000104549        363        300        392        249        446
ENSG00000104611        781        562       1675        402       1213
ENSG00000104613        926        898        886        567        944
ENSG00000104626        438        341        451        311        462
ENSG00000104635       1191       1272       1325        717       1843
ENSG00000104643        348        312        453        263        424
ENSG00000104660        557        444        686        406        731
ENSG00000104671        205        218        263        193        247
ENSG00000104679        350        306        321        162        381
ENSG00000104687        852       1475        858        991       1269
ENSG00000104689         33         31         35         34         54
ENSG00000104691        173        160        184        122        159
ENSG00000104695       1563       1973       1873       1814       1671
ENSG00000104714        242        253        325        186        363
ENSG00000104722         17         30         57         27         55
ENSG00000104723       1550       1082       1645        911       1405
ENSG00000104725         12         36         12          2         21
ENSG00000104728       1959       1558       1991       1007       2065
ENSG00000104731        178        135        175         90        194
ENSG00000104738        608        397        707        263        573
ENSG00000104755          0          0          0          0          0
ENSG00000104756       1266       1825       1478       1641       1695
ENSG00000104760          0          0          0          0          0
ENSG00000104763       2565       1837       3986       2839       3656
ENSG00000104765       7464       6731       8814       5899       9059
ENSG00000104774       1939       1906       2294       1205       1871
ENSG00000104783          4          3         15          2          2
ENSG00000104804         12         16          8          5         10
ENSG00000104805       5352       4523       6762       4028       6515
ENSG00000104808          2          7          5          1          3
ENSG00000104812       1426       1427       1965        909       1376
ENSG00000104814          5          0          1          3          1
ENSG00000104818          2          0          0          0          0
ENSG00000104823        563        772        684        418        693
ENSG00000104824       1953       1550       2247       1102       2429
ENSG00000104825        359        465        442        293        448
ENSG00000104826          0          0          1          1          1
ENSG00000104827          0          0          1          0          0
ENSG00000104833          4          6          8          1          5
ENSG00000104835          5          6         10          6          2
ENSG00000104848          0          1          4          0          2
ENSG00000104852       3920       4593       4232       2563       4494
ENSG00000104853       1799       1866       2353       1450       2441
ENSG00000104856        129         82        184         81        170
ENSG00000104859        370        455        480        229        487
ENSG00000104863         51         28         46         12         43
ENSG00000104866        657        496        634        285        723
ENSG00000104870       2954       2424       3004       1940       3259
ENSG00000104872        618        591        689        409        619
ENSG00000104879          2          2          2          2          3
ENSG00000104880        348        342        340        240        323
ENSG00000104881        135        112        150         87        150
ENSG00000104883         35         23         40         22         48
ENSG00000104884        359        318        399        244        463
ENSG00000104885        286        305        275        205        340
ENSG00000104886        449        523        426        328        454
ENSG00000104888          5          4          9         10          8
ENSG00000104889         99         72         93         38         84
ENSG00000104892          0          0          2          0          0
ENSG00000104894         21         13         36          7         50
ENSG00000104897        586        467        558        330        526
ENSG00000104899          9         24          9          6         16
ENSG00000104901          2          3          8          1          6
ENSG00000104903          1          9          3          5          1
ENSG00000104904       6688       6912       8632       4967       7969
ENSG00000104907        415        510        400        214        437
ENSG00000104915        670        581        650        348        658
ENSG00000104918          0          0          0          0          0
ENSG00000104921          0          0          0          0          0
ENSG00000104936        856       1053       1221       1244        891
ENSG00000104938          0          1          0          0          0
ENSG00000104941          0          0          1          0          0
ENSG00000104946       1079       1050       1311        815       1206
ENSG00000104951          9          0         15          1         14
ENSG00000104953          9         17         11         10          4
ENSG00000104957        411        408        465        268        411
ENSG00000104960        577        455        587        306        631
ENSG00000104964       2969       3669       3601       2341       3441
ENSG00000104967          1          2          7          1          5
ENSG00000104969        980       1041       1122        646       1221
ENSG00000104970          1          0          0          0          0
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ENSG00000104973        624        623        695        465        663
ENSG00000104974          0          0          0          0          0
ENSG00000104976        332        371        325        210        234
ENSG00000104979        993        934       1145        526       1341
ENSG00000104980        371        387        441        251        493
ENSG00000104983        109         89        122         65        126
ENSG00000104998         20         10         59         35         70
ENSG00000105011         18         12         16          8          8
ENSG00000105048          6          4         29         15         17
ENSG00000105053        460        379        577        349        579
ENSG00000105058       1417       1589       1787       1174       1952
ENSG00000105063       1313       1283       1684        917       1823
ENSG00000105072        185        119        211         92        211
ENSG00000105085         84         83        109         68        112
ENSG00000105088         35          9         52          9        128
ENSG00000105122          0          3          4          0          1
ENSG00000105127        543        642        612        365        674
ENSG00000105131          2          0          2          2          0
ENSG00000105135        857        726        808        459        717
ENSG00000105136        173        144        252        122        363
ENSG00000105137       1260       1495       1378        985       1273
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ENSG00000105171        438        411        510        298        526
ENSG00000105173         42         31         81         26        106
ENSG00000105176       1342       1215       1704        972       1437
ENSG00000105185        671        848        699        496        841
ENSG00000105186        510        615        531        417        555
ENSG00000105193      10090      10370      10806       4768       9096
ENSG00000105197        678        645        757        366        707
ENSG00000105198          0          0          0          0          0
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ENSG00000105221       3156       2468       3610       1616       3112
ENSG00000105223       5154       4041       8242       4186       7666
ENSG00000105227        250        141        256        139        253
ENSG00000105229        240        279        252        150        314
ENSG00000105245       2438       2133       2600       1352       4457
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ENSG00000105248        154        168        211        106        211
ENSG00000105251          0          0          0          0          0
ENSG00000105254        911       1008        994        609        874
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ENSG00000105258         61         53         84         37         74
ENSG00000105261          0          0          0          0          0
ENSG00000105270       1976       1820       2821       1898       3466
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ENSG00000105281       4055       4991       5364       3886       5707
ENSG00000105287        432        369        522        253        523
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ENSG00000105290         93         45        122         43        150
ENSG00000105298        320        296        395        199        358
ENSG00000105321        318        358        445        254        393
ENSG00000105323       4858       4245       5209       2801       5455
ENSG00000105325        905        684        922        438        980
ENSG00000105327        490        267        396        126        354
ENSG00000105329       2170       1701       1948        904       3081
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ENSG00000105341        611        584        663        331        759
ENSG00000105352          0          0          0          0          0
ENSG00000105355       2622       2501       2805       1342       2096
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ENSG00000105372      22349      21944      15805       7955      14659
ENSG00000105373       4640       4794       3996       1930       3832
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ENSG00000105379        214        173        147        119        163
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ENSG00000105388          0          0          0          0          0
ENSG00000105392          1          0          0          0          0
ENSG00000105393        235        233        202        177        196
ENSG00000105397       1204       1065       1134        560       1311
ENSG00000105398          0          0          0          1          0
ENSG00000105401       2251       2252       2711       1417       2622
ENSG00000105402       1471       1707       1930       1281       1698
ENSG00000105404       1816       2059       1669       1108       1694
ENSG00000105409          2          1         18          2          6
ENSG00000105419        660        965        844        678        959
ENSG00000105426       2808       3167       3631       3411       3540
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ENSG00000105438       2735       2388       3549       2136       3855
ENSG00000105443        651        569        683        330        735
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ENSG00000105483        319        185        556        257        605
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ENSG00000105519        125        131        134         99         98
ENSG00000105520       1028        915       1103        513       1234
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ENSG00000105568       5428       4755       5885       3900       6011
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ENSG00000105583        459        366        363        278        300
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ENSG00000105607        182        217        196        139        160
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ENSG00000105618        381        356        433        262        448
ENSG00000105619        137        127        184         94        118
ENSG00000105639         78         78        107         72         37
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ENSG00000105677        657        601        780        417        771
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ENSG00000105700        784        693        880        487        937
ENSG00000105701       5519       4905       6599       3665       6207
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ENSG00000105722        659        641        521        287        712
ENSG00000105723        574        577        624        400        736
ENSG00000105726        825        953        912        589        985
ENSG00000105732        216        181        209         80        236
ENSG00000105737        184        102        198         86        131
ENSG00000105738        298        249        285        129        390
ENSG00000105750         44         30         59         20         68
ENSG00000105755        378        251        722        299        399
ENSG00000105767         27         18         51         19         60
ENSG00000105771        678        492        751        325        789
ENSG00000105778        737        702        705        555        870
ENSG00000105784         48         41        113         60         39
ENSG00000105792        150        180        156        203        205
ENSG00000105793        292        282        376        226        347
ENSG00000105808        119        103        231        142        168
ENSG00000105810       1362        785       1956        643       2809
ENSG00000105819        914        829       1000        703       1024
ENSG00000105821        375        358        339        257        459
ENSG00000105825         59         80        134         42       1607
ENSG00000105829        455        345        467        236        659
ENSG00000105835       1749       3256       1829       2624       2382
ENSG00000105849        295        301        354        222        337
ENSG00000105851          0          0          0          0          0
ENSG00000105852          0          1          0          0          0
ENSG00000105854        898        871       1368        904       1480
ENSG00000105855       2526       1294       2381        969       2549
ENSG00000105856       1541       1188       1754       1094       2036
ENSG00000105865         71         50         79         38         74
ENSG00000105866        150         97        164         93        125
ENSG00000105875        348        273        339        169        373
ENSG00000105877         19         18         17          7         20
ENSG00000105879        405        337        521        356        531
ENSG00000105880          3          4         11          4          0
ENSG00000105887       2362       1881       3119       1901       2716
ENSG00000105889        149        282        205        243        102
ENSG00000105894       5215       2723       6692       2846       7624
ENSG00000105926        230        215        209        182        315
ENSG00000105928        815        631        885        530       1150
ENSG00000105929          0          0          0          0          1
ENSG00000105939       1599       1481       1748       1180       1619
ENSG00000105948        197        119        185        125        197
ENSG00000105953       1256        983       1347        846       1194
ENSG00000105954          1          0          1          0          0
ENSG00000105963          2          2          9         20          4
ENSG00000105967          1          3          4          0          4
ENSG00000105968       1510       1273       1659        981       1540
ENSG00000105971        993       1228       1431       1367       1618
ENSG00000105974       8655      13298       9958      10775      12021
ENSG00000105976        520        694       1294        783        711
ENSG00000105982         21         18         29         16         27
ENSG00000105983        764        584        921        520       1022
ENSG00000105988          3          2          2          5          9
ENSG00000105989        562         47       1575        106        106
ENSG00000105991         20         24         27         18         27
ENSG00000105993       1783       1968       2022       1597       2497
ENSG00000105996         78         42         68         22        102
ENSG00000105997        191        116        141         47        226
ENSG00000106003         23          3         14          2         44
ENSG00000106004        200        154        169         84        120
ENSG00000106006          0          0          0          0          0
ENSG00000106009        565        440        456        243        500
ENSG00000106012        727        625        845        493       1043
ENSG00000106013          8          3          5          7          6
ENSG00000106018          1          4          2          7          1
ENSG00000106025         27         35         28         18         50
ENSG00000106028        731        639        788        441        847
ENSG00000106031          0          0          0          0          0
ENSG00000106034       1133       1530       2432       2814       1253
ENSG00000106038          0          0          0          0          0
ENSG00000106049       1322        950       2095       1027       1737
ENSG00000106052       2788       2633       3929       2248       4018
ENSG00000106066          0          0          7          2          1
ENSG00000106069         16          4         20          5          7
ENSG00000106070        677        857        632        380        918
ENSG00000106077        107         64        143         38        114
ENSG00000106078          0          0          0          0          0
ENSG00000106080       1201        870       1510        770       1365
ENSG00000106086        401        499        350        378        498
ENSG00000106089        136        149        120         54        175
ENSG00000106100        217        174        247        113        205
ENSG00000106105       3061       2268       3899       1652       4016
ENSG00000106113          1          1          1          0          2
ENSG00000106123       1399       3130       2425       2581        708
ENSG00000106125         11          9         20         13         10
ENSG00000106128          0          0          0          0          2
ENSG00000106133        193        168        179         64        180
ENSG00000106144        482        338        430        243        502
ENSG00000106153       2173       2026       2302       1221       2041
ENSG00000106178          1          4          1          0          2
ENSG00000106211       7178       9816       9456       6386       7533
ENSG00000106236          0          8          1          0          4
ENSG00000106244       1804       1791       2273       1273       2452
ENSG00000106245        398        349        400        289        432
ENSG00000106246         30         37         19         25         36
ENSG00000106258         39         31         50         30         17
ENSG00000106261       3115       2019       4110       1724       4185
ENSG00000106263       2618       2634       2922       1738       3046
ENSG00000106266        941        747        856        575        863
ENSG00000106268        171        181        173        122        185
ENSG00000106278          0          0          1          1          0
ENSG00000106290        672        548        741        376        686
ENSG00000106299       1155       1354       1328       1080       1585
ENSG00000106302          2          1          0          0          0
ENSG00000106304          0          0          0          0          0
ENSG00000106305        133        152        148         90        161
ENSG00000106327          3          5          6          2          8
ENSG00000106328          0          1          0          0          0
ENSG00000106330        317        286        381        142        377
ENSG00000106331          0          0          0          0          0
ENSG00000106333       8525       4541       7829       3066       7734
ENSG00000106336          5          5         19          3          7
ENSG00000106341          0          0          0          0          0
ENSG00000106344        434        422        493        322        528
ENSG00000106346        211        177        273        148        322
ENSG00000106348        820        991        847        509        826
ENSG00000106351        177        143        152        106        151
ENSG00000106355        318        313        337        214        309
ENSG00000106366       3617       4066       7505       5467       5212
ENSG00000106367        979        840        993        548       1151
ENSG00000106384          0          0          0          0          0
ENSG00000106392        466        410        777        441        753
ENSG00000106397       1629       1839       1968       1293       1610
ENSG00000106399        129         97        125         86         99
ENSG00000106400        810        788        892        480        885
ENSG00000106404        210        220        166        107        170
ENSG00000106410          0          0          0          0          0
ENSG00000106415        157        212        243        233        217
ENSG00000106436          0          0          0          0          0
ENSG00000106443        695        502        754        328        976
ENSG00000106459        222        195        258        122        278
ENSG00000106460       1432       1104       1743       1234       1814
ENSG00000106462        155         81        136         53        195
ENSG00000106477        216        128        278        117        247
ENSG00000106479        660        481        588        319        602
ENSG00000106483        188        115       1874        603        239
ENSG00000106484        733        180       2352        447        975
ENSG00000106511          4          4          4          6         13
ENSG00000106524        439        258        455        173        465
ENSG00000106526          8          4         17          2          6
ENSG00000106536          0          0          0          0          0
ENSG00000106537         17          9         17          7         15
ENSG00000106538       3707       2516       4032       1583       1530
ENSG00000106540          0          0          0          0          0
ENSG00000106541          0          0          0          0          0
ENSG00000106546       1446       1006       2527       1152       2138
ENSG00000106554       1314       1162       1354        703       1470
ENSG00000106560         17         14          6          5          1
ENSG00000106565       2045       2228       1052        728         27
ENSG00000106571        990        655       1035        386       1173
ENSG00000106588         73         43         49         32         49
ENSG00000106591        513        567        636        438        619
ENSG00000106603        452        323        567        217        623
ENSG00000106605        547        499        482        326        586
ENSG00000106608        631        515        646        395        657
ENSG00000106609       2696       2585       3576       2278       3239
ENSG00000106610         48         36        115         50         99
ENSG00000106615       1512       2375       1745       2228       1571
ENSG00000106617        314       1074        871       1283        570
ENSG00000106624      10109       5690      18088      10323      14936
ENSG00000106628       1137        993       1235        575       1223
ENSG00000106631          0          0          2          1          2
ENSG00000106633         42         33         39         12         33
ENSG00000106635        608        597        786        497        689
ENSG00000106636       2157       1941       2302       1479       2431
ENSG00000106638        686        606        766        448        727
ENSG00000106648          0          0          0          0          0
ENSG00000106665       2064       1364       2207        951       2853
ENSG00000106682       6598       5821       6858       3938       6768
ENSG00000106683       1394        988       1114        575       1625
ENSG00000106686         15          9         20          9         12
ENSG00000106688        257        356       1027        672        269
ENSG00000106689          0          0          0          0          0
ENSG00000106692        974        931       1286        862       1537
ENSG00000106701        117        121        114         82        133
ENSG00000106714         25         30         43         50          1
ENSG00000106723       2074       1346       2351       1198       2469
ENSG00000106733        295        257        301        195        260
ENSG00000106771       2206       2068       2249       1521       2461
ENSG00000106772       3641       5456       4636       4103       4326
ENSG00000106780       1278       1310       1376       1134       1512
ENSG00000106785        297        138        311        121        299
ENSG00000106789          4          8         17          9          6
ENSG00000106799       3244       3684       5823       1910       3319
ENSG00000106803        892        862        937        519        847
ENSG00000106804        215        217        299        206        193
ENSG00000106809       3528       1701       3575       1182       1195
ENSG00000106819       1193        926       3552       2986       1219
ENSG00000106823        592        307       1473        840        922
ENSG00000106829        975        663        870        537       1203
ENSG00000106852          0          0          0          0          0
ENSG00000106853       1196       1365       1638        794       2593
ENSG00000106868        518        431        571        369        603
ENSG00000106927          1          6          9          3         10
ENSG00000106948        656        340        888        258        509
ENSG00000106952          0          0          0          0          1
ENSG00000106976       1578        419       1258        226       1395
ENSG00000106991       3261       2116       3103       1266       3902
ENSG00000106992        211        176        225        119        225
ENSG00000106993        348        447        407        382        380
ENSG00000107014          0          0          0          0          0
ENSG00000107018          0          0          0          0          0
ENSG00000107020        214        228        208        149        209
ENSG00000107021       1088        870       1185        680       1075
ENSG00000107036       1359       1229       1740        980       1738
ENSG00000107077        481        324        432        225        443
ENSG00000107099          9          9         19         11         28
ENSG00000107104        634        921       1087       1331        846
ENSG00000107105          1          2          2          1          1
ENSG00000107130       1424        848       1216        504       1418
ENSG00000107140        535        575        506        323        755
ENSG00000107147          0          2          1          0          2
ENSG00000107159         20          5         27         10         45
ENSG00000107164       1113       1027       1309        767       1386
ENSG00000107165          0          1          0          0          0
ENSG00000107175        964        781       1128        596       1096
ENSG00000107185        910        826        963        509       1022
ENSG00000107186       1481       1051       2236        990       2478
ENSG00000107187          0          1          0          0          0
ENSG00000107201        389        242        483        273        451
ENSG00000107223       2461       2191       2857       1404       2954
ENSG00000107242          1          1          2          1          0
ENSG00000107249        548        613        727        511        685
ENSG00000107262        579        612        666        416        617
ENSG00000107263       1702       1504       2045       1364       1762
ENSG00000107281        898        843        813        475        737
ENSG00000107282        433        339        534        250        583
ENSG00000107290       3112       2715       3398       1877       3487
ENSG00000107295          1          0          1          0          1
ENSG00000107317       8376       5197       4967       2681       4155
ENSG00000107331       1242        837       1520        733       1433
ENSG00000107338        180         73        158         43        185
ENSG00000107341       1610       1341       1786       1219       2096
ENSG00000107362        203        196        174        174        172
ENSG00000107371        141        148        182        107        207
ENSG00000107372       3683       4090       5431       6717       4454
ENSG00000107404       1113       1132       1091        642       1015
ENSG00000107438       2093       4077       2439       2455       3434
ENSG00000107443        151        109        121         77        154
ENSG00000107447          0          0          0          0          0
ENSG00000107485          0          2          3          0          0
ENSG00000107518         16          7         23         11         45
ENSG00000107521       1893       1876       2142       1163       2343
ENSG00000107537        685        669        833        519        816
ENSG00000107551        513        578        405        200       1472
ENSG00000107554        864        754        969        404        972
ENSG00000107560        542        573        686        443        731
ENSG00000107562      48832       9539      24653       4537      55670
ENSG00000107566       1795       1484       1883       1089       1858
ENSG00000107581       8172       8326       8825       6086      10670
ENSG00000107593          0          0          0          0          2
ENSG00000107611         51         12         61         16         61
ENSG00000107614        122         98        134         70        138
ENSG00000107618          0          1          0          0          0
ENSG00000107623       6735       3622       5598       1465       2474
ENSG00000107625       1027        830       1036        606       1026
ENSG00000107643        532        412        548        353        613
ENSG00000107651       1249       1105       1188        822       1505
ENSG00000107669        576        437        539        385        637
ENSG00000107672        154        170        207        147        182
ENSG00000107679        546        594        654        486        730
ENSG00000107719         19         11          7         14          7
ENSG00000107731        911        457        874        255        589
ENSG00000107736          7          3          8          6          6
ENSG00000107738       4153       4941       7113       4121       2657
ENSG00000107742          5         10          8          6          6
ENSG00000107745       1624       1198       1965       1102       2152
ENSG00000107758       1449       1413       1722       1300       1777
ENSG00000107771       1271       1020       1332        853       1529
ENSG00000107779       1089        935       1025        638       1134
ENSG00000107789        571        486        632        440        665
ENSG00000107796       1169       1911       2455       3097       1734
ENSG00000107798       1256       1209       1488       1052       1157
ENSG00000107807          0          1          0          0          0
ENSG00000107815        107        124        128         71        151
ENSG00000107816       3236       3145       2619       1686       2744
ENSG00000107819       2031       2030       1963       1330       1750
ENSG00000107821        549        239        793        225        446
ENSG00000107829        423        426        583        437        578
ENSG00000107831          0          0          1          0          0
ENSG00000107833        268        247        249        104        241
ENSG00000107854       2734       1934       2468       1357       2871
ENSG00000107859          1          3          1          1          4
ENSG00000107862       2811       2146       3047       1622       3042
ENSG00000107863       4940       4660       5437       3629       6470
ENSG00000107864         37         28         54         37         38
ENSG00000107872        117        138         97         61        101
ENSG00000107874        941        876        980        522       1060
ENSG00000107882        841        531       1004        422       1080
ENSG00000107890        267        233        401        168        502
ENSG00000107897        676        623        794        456        916
ENSG00000107902        308        229        289        141        321
ENSG00000107929        966       1077       1130       1101       1183
ENSG00000107937        606        776        753        543        837
ENSG00000107938        321        269        390        205        432
ENSG00000107949        403        418        511        295        542
ENSG00000107951        259        245        275        161        281
ENSG00000107954          5          9         16          6          6
ENSG00000107957       9138       8071      10254       5835       9851
ENSG00000107959        971       1038       1490        968       1699
ENSG00000107960        267        182        343        197        340
ENSG00000107968        371        599        472        585        332
ENSG00000107984        297        367        569        375        549
ENSG00000108001        150        191        323         90          8
ENSG00000108010        659        666        720        442        730
ENSG00000108018          0          0          0          0          0
ENSG00000108021       1215       1074       1377        769       1797
ENSG00000108039       1040        992       1195        712       1513
ENSG00000108055       1515       1290       1586       1100       1812
ENSG00000108061       1189       1225       1279       1013       1430
ENSG00000108064        404        306        399        213        496
ENSG00000108091       1561       1538       1628        990       1676
ENSG00000108094        838        693        916        572       1016
ENSG00000108100       1788       1786       2012       1469       2279
ENSG00000108106        270        284        284        148        290
ENSG00000108107      12860      10832      11022       5060      12084
ENSG00000108175       4333       2816       4524       1649       4039
ENSG00000108176         43         26         20          6         21
ENSG00000108179        506        575        487        381        771
ENSG00000108187        176        164        226        120        251
ENSG00000108219        907        843        849        487        956
ENSG00000108231         37          7         61         18         13
ENSG00000108239        646        609        845        557        648
ENSG00000108242          0          2          0          0          0
ENSG00000108244          0          0          0          0          0
ENSG00000108255          0          0          1          0          2
ENSG00000108256       2201       2376       2384       1860       2589
ENSG00000108262        990       1388        912        880       1268
ENSG00000108264        218        209        316        186        295
ENSG00000108270        711        732        724        548        833
ENSG00000108272         48         41         30         21         70
ENSG00000108278        307        222        347        196        375
ENSG00000108292       2035       1934       2050       1286       2163
ENSG00000108294        873        815       1005        570       1021
ENSG00000108296        447        361        448        304        533
ENSG00000108298      20121      18884      22649      10267      20982
ENSG00000108306        199        146        239        100        224
ENSG00000108309          5         11         12         14         16
ENSG00000108312       2239       2042       2582       1356       2927
ENSG00000108342          1          0          0          0          1
ENSG00000108344       1784       1590       2171       1147       2182
ENSG00000108349       2059       1735       2129       1227       2600
ENSG00000108352         58         33         86         23         95
ENSG00000108370         40         33         17         12         21
ENSG00000108375          0          0          0          0          0
ENSG00000108379         51         47         77         41         69
ENSG00000108381        330        416        277        249        247
ENSG00000108384        162        138        191        111        179
ENSG00000108387         15         37          9         19          6
ENSG00000108389       1016        934       1027        575        961
ENSG00000108395        833        691        964        594       1236
ENSG00000108405          0          0          0          1          0
ENSG00000108406       1579       1242       1816       1159       1793
ENSG00000108417          0          0          0          0          0
ENSG00000108423         52         43         54         36         53
ENSG00000108424       4448       4378       5292       3544       5568
ENSG00000108433        455        321        470        250        447
ENSG00000108439        115        115        180        107        178
ENSG00000108442          0          0          0          0          0
ENSG00000108443        694        563        822        498        921
ENSG00000108448        201        136        221         96        330
ENSG00000108452          1          0          2          0          0
ENSG00000108465        999        968       1125        633       1077
ENSG00000108468       1743       1136       1945        817       1941
ENSG00000108469        411        326        468        228        412
ENSG00000108474        143         87        162         54        128
ENSG00000108479        210        203        202        111        186
ENSG00000108506        293        213        266        200        289
ENSG00000108509        712        687        837        533        693
ENSG00000108510       1537       1356       1843       1193       1943
ENSG00000108511         56         47         47         46          8
ENSG00000108515         79        156         70         64         81
ENSG00000108516          0          0          0          0          0
ENSG00000108518       3805       4072       4571       3162       3923
ENSG00000108523       1263       1302       1476       1025       1373
ENSG00000108528        656        547        640        330        643
ENSG00000108551         42        277         62        148         17
ENSG00000108556          2          4         18         20          4
ENSG00000108557        898        602        838        374        833
ENSG00000108559        350        326        474        278        514
ENSG00000108561        641        605        648        413        720
ENSG00000108576          1          0          5          0          3
ENSG00000108578        402        374        461        264        499
ENSG00000108582       4533       4578       8270       7638       6636
ENSG00000108587        660        575        808        438        971
ENSG00000108588       1128       1237       1388        962       1421
ENSG00000108590         69         64         63         40         61
ENSG00000108591        546        555        613        384        598
ENSG00000108592       1219       1424       1489       1008       1466
ENSG00000108599        663        613        839        481        850
ENSG00000108602          3          0         14          2         24
ENSG00000108604       1339       3593       1587       1986       1403
ENSG00000108622          5          1          8          2          1
ENSG00000108639        205        199        386        378        332
ENSG00000108641        215        103        260         98        226
ENSG00000108651        566        531        670        374        689
ENSG00000108654      12625      12513      15121       9228      15922
ENSG00000108666        135        104        161        100        121
ENSG00000108669        371        311        431        263        374
ENSG00000108671       1039        939       1174        793       1363
ENSG00000108679       3267       2469       6338       3434       3278
ENSG00000108684         15          0         16          0         12
ENSG00000108688         17          0         20          2         38
ENSG00000108691        451        263       1240        347       2251
ENSG00000108700         21          0         48          1         55
ENSG00000108702          0          0          0          0          0
ENSG00000108733        244        173        305        138        246
ENSG00000108753          1          0          1          0          0
ENSG00000108759          1          0          1          1          0
ENSG00000108771        295        254        303        179        294
ENSG00000108773        618        611        558        283        555
ENSG00000108774        782        806        902        603        910
ENSG00000108784       1321       1283       1372        893       1174
ENSG00000108785         46         38         59         27         57
ENSG00000108786         95         89        140         81        162
ENSG00000108788        507        543        561        349        543
ENSG00000108797       1889        988       2651        926       1749
ENSG00000108798          0          0          0          0          3
ENSG00000108799       1107       1153       1497       1166       1306
ENSG00000108813          1          3          3          0          2
ENSG00000108819       1643       1246       1705        982       1912
ENSG00000108821     143038      52204     157553      37006     182901
ENSG00000108823          4          5         19         13          8
ENSG00000108825          0          0          0          0          0
ENSG00000108826        375        327        440        212        455
ENSG00000108828      15568       7437      18687       7558      15261
ENSG00000108829       1416       1941       1486       1099       1866
ENSG00000108830        214         28        445         30        247
ENSG00000108839         47         34         52         24         66
ENSG00000108840       2491       2538       2486       2100       2208
ENSG00000108846        237        341        322        266        424
ENSG00000108848       3117       2814       3406       2193       3691
ENSG00000108849          0          0          0          0          0
ENSG00000108852        202        108        197         86        157
ENSG00000108854       2573       2369       5732       1907       4119
ENSG00000108861       1812       2492       1816       1360       2372
ENSG00000108878          0          0          0          0          0
ENSG00000108883        915        813       1016        608       1274
ENSG00000108924         13         50         28         46         27
ENSG00000108932         17         26         38         12         69
ENSG00000108946       6753       6766       7641       5861       8815
ENSG00000108947         77         64        121         67        152
ENSG00000108950        698       1004        968       1172        595
ENSG00000108953       6059       6062       7966       5049       8050
ENSG00000108958        236        213        299        186        290
ENSG00000108960        832       2749        812       1746       1444
ENSG00000108961          7         11          9         12         15
ENSG00000108963        373        353        394        202        341
ENSG00000108984        125         87        186         84         75
ENSG00000109016        220        242        404        262        289
ENSG00000109046       3437       3086       5439       3059       5101
ENSG00000109047          0          1          0          0          1
ENSG00000109061          0          1          0          1          0
ENSG00000109062        202        195        192        117        261
ENSG00000109063         31         32         39         22         28
ENSG00000109065        599        533        552        297        609
ENSG00000109066        502        488        580        428        581
ENSG00000109072          9          8         24         10         27
ENSG00000109079        837        846       1078        691       1138
ENSG00000109083        323        306        339        163        399
ENSG00000109084        206        204        116        109        222
ENSG00000109089        563        712        565        375        796
ENSG00000109099       7809       5300       8802       3933       9759
ENSG00000109101          0          0          0          0          0
ENSG00000109103        456        363        509        178        592
ENSG00000109107        370        205        406        141        367
ENSG00000109111       3791       3408       4677       2561       5028
ENSG00000109113       2210       1994       2598       1418       2611
ENSG00000109118        898        731        920        500        987
ENSG00000109132          0          0          0          0          0
ENSG00000109133        642        697        796        592        790
ENSG00000109158          0          0          0          0          0
ENSG00000109163          3          1          8          2          4
ENSG00000109171        937        938       1053        695       1222
ENSG00000109180       1606       1357       2319       1395       2190
ENSG00000109181          0          0          0          0          0
ENSG00000109182          0          0          0          0          0
ENSG00000109184       1120       1304       1072        837       1348
ENSG00000109189        477        620        568        527        618
ENSG00000109193          1          0          0          0          0
ENSG00000109205          0          0          0          0          0
ENSG00000109208          0          0          0          0          0
ENSG00000109220        240        221        309        218        248
ENSG00000109255          0          0          0          0          0
ENSG00000109265        147         49        133         32         39
ENSG00000109270        646        591        666        453        727
ENSG00000109272          1          0          1          1          8
ENSG00000109320       1239        943       1200        648       1340
ENSG00000109321          5          2          2          0         11
ENSG00000109323       1880       1283       2661       1349       1894
ENSG00000109332       5247       5174       5947       4004       6336
ENSG00000109339       1111        659        973        350       1233
ENSG00000109381        785        676        863        506        923
ENSG00000109390        355        274        442        241        430
ENSG00000109424          0          0          0          0          1
ENSG00000109436        862        807       1112        572       1006
ENSG00000109445        618        586        596        436        702
ENSG00000109452        164        174        235        119        322
ENSG00000109458        949        667       1068        507        990
ENSG00000109466        329        358        406        232        465
ENSG00000109471          0          0          0          0          0
ENSG00000109472      11294       8196      12321       5903       6538
ENSG00000109475       7003       6292       6080       4087       5133
ENSG00000109501       1575       2000       2071       1487       1414
ENSG00000109511          0          0          1          1          7
ENSG00000109519        292        365        348        215        346
ENSG00000109534        156        108        134         84        165
ENSG00000109536        486        491        584        365        662
ENSG00000109572       2060       1282       2301        951       2556
ENSG00000109576        171        135        142         37        215
ENSG00000109586        292        353        358        296        437
ENSG00000109606       2629       2359       2612       1559       2671
ENSG00000109610       3475       2491       6784       3725       3336
ENSG00000109618        242        155        302        177        263
ENSG00000109625         59         11         68         10         69
ENSG00000109654       1783        824       1863        525       1680
ENSG00000109667        106        104        160        119        141
ENSG00000109670        375        270        450        201        498
ENSG00000109674         70         21         94         29         88
ENSG00000109680        765        416       1270        385        718
ENSG00000109684          0          0          0          0          0
ENSG00000109685        981        670       1126        506       1055
ENSG00000109686       4090       6212       5262       5009       5760
ENSG00000109689       1511        784       2180        493       1296
ENSG00000109705          4          8         18          8         10
ENSG00000109736        967       1164       1038        690        904
ENSG00000109738        281        165        499        312        524
ENSG00000109743        198        203        422        306        458
ENSG00000109756       1363       1124       1637        970       2151
ENSG00000109758          4          3          4          3          9
ENSG00000109762        338        394        395        282        534
ENSG00000109771         43         27         31         16         56
ENSG00000109775        390        260        450        178        429
ENSG00000109787       1641       1176       1627        977       1756
ENSG00000109790       1232        968       1664        867       1946
ENSG00000109794        191         88        195         57         50
ENSG00000109805         78         53         60         25         66
ENSG00000109814       1476       1819       2065       1492       1966
ENSG00000109819        136        104         91         45        438
ENSG00000109832          0          1          0          0          0
ENSG00000109846       1288       1362       1960       1696       2034
ENSG00000109851          1          0          0          0          0
ENSG00000109854        392        428        517        371       1028
ENSG00000109861       1753       3264       3556       3983       3786
ENSG00000109881         87         34        118         20        120
ENSG00000109906          4        739          5        429          1
ENSG00000109911        171        119        180         85        170
ENSG00000109917        363        385        464        283        532
ENSG00000109919       1161       1119       1353        958       1437
ENSG00000109920       1151       1274       1377        920       1593
ENSG00000109927         35         19         39         31         32
ENSG00000109929        394        342        523        330        584
ENSG00000109943          0          2          1          1          0
ENSG00000109944        140        100        203         91        133
ENSG00000109956          0          0          0          0          0
ENSG00000109971      17599      13887      26410      13016      35609
ENSG00000109991          0          0          0          0          1
ENSG00000110002        998        718       1106        421       1800
ENSG00000110011        379        323        425        191        414
ENSG00000110013       1517       1090       1644        961       1939
ENSG00000110025          8         11         15          9         14
ENSG00000110031        153         81        172         70        122
ENSG00000110042        831       1068        678        301        620
ENSG00000110046        758        739        791        542        842
ENSG00000110047       1838       2067       2435       1576       1509
ENSG00000110048       1621       1412       1766       1017       2083
ENSG00000110057        260        355        277        252        356
ENSG00000110060        168        130        204         91        229
ENSG00000110063        227        165        232         82        262
ENSG00000110066        556        518        671        433        735
ENSG00000110074        253        234        307        159        298
ENSG00000110075       1371       1238       1449        942       1539
ENSG00000110076          1          0          4          2          6
ENSG00000110077          0          0          0          0          1
ENSG00000110079          0          0          0          0          0
ENSG00000110080        800        811        771        432        657
ENSG00000110090       1497       2638       1734       1678       2160
ENSG00000110092       9529       7154      17601      10868      15213
ENSG00000110104        190        193        174        101        198
ENSG00000110107       1459       1291       1491        708       1529
ENSG00000110108       2060       2342       2095       1548       2020
ENSG00000110148          0          0          2          0          0
ENSG00000110169         20          7         20          8         30
ENSG00000110171        481        463        396        238        394
ENSG00000110172        514        525        583        348        694
ENSG00000110195          8          5         14          9          9
ENSG00000110200         41         48         61         30         41
ENSG00000110203         21          7         47          9         21
ENSG00000110218        745        832        603        433        772
ENSG00000110237       2354       2666       2756       1811       2499
ENSG00000110243          1          1          1          0          0
ENSG00000110244          0          0          0          0          0
ENSG00000110245          0          0          0          0          0
ENSG00000110274        852        744       1088        518       1056
ENSG00000110315       1099        951       1483       1192       1443
ENSG00000110318        355        372        611        318        687
ENSG00000110321      30798      25513      34768      19021      33605
ENSG00000110324          1          1          0          0          0
ENSG00000110328         84         46         71         41         68
ENSG00000110330       1455       1266       1517       1089       1558
ENSG00000110344       1107        970       1397        736       1312
ENSG00000110347          0          0          7          2          2
ENSG00000110367       2554       1826       2599       1790       2687
ENSG00000110375          1          1          2          1          7
ENSG00000110395        880        832        748        581       1092
ENSG00000110400        210        118        216         59        278
ENSG00000110422       2000       2077       2153       2194       2474
ENSG00000110427         64         31        201        102        161
ENSG00000110429        724        629        879        537        665
ENSG00000110435        485        376        577        316        538
ENSG00000110436        287        139        259        157        345
ENSG00000110442        443        334        538        241        633
ENSG00000110446        273        308        307        233        378
ENSG00000110448          0          0          0          0          0
ENSG00000110455        350        313        573        306        693
ENSG00000110484          0          0          0          0          0
ENSG00000110492       2075       1394       1903        751       2381
ENSG00000110497        673        620        750        439        802
ENSG00000110514        755        648        830        449        728
ENSG00000110536         27         27         33         30         52
ENSG00000110583        519        291        487        182        596
ENSG00000110619       1118        873       1282        663       1322
ENSG00000110628        203        286        192        175        205
ENSG00000110651      16123      13132      18490      11924      17568
ENSG00000110660         51         40         22         18         68
ENSG00000110665          1          1          0          0          3
ENSG00000110675          3          6          0          1          0
ENSG00000110680          0          0          3          0          0
ENSG00000110693         15          8         10          8         23
ENSG00000110696       2637       2521       3037       2020       3033
ENSG00000110697        584        681        684        343        835
ENSG00000110700       6758       6395       6639       3567       5951
ENSG00000110711        653        631        829        435        678
ENSG00000110713       2180       2079       2311       1653       2745
ENSG00000110717        472        451        673        281        582
ENSG00000110719        941        945        904        593       1026
ENSG00000110721         73        117         67         69        104
ENSG00000110723        339        274        426        335        385
ENSG00000110756        499        999        620       1229        639
ENSG00000110768       1227       1296       1351       1100       1530
ENSG00000110777          3          0          1          0          0
ENSG00000110786          0          1          0          0          0
ENSG00000110799         18          9         30          4         40
ENSG00000110801        118        103        131         66        142
ENSG00000110811       1339        797       1719        848       1925
ENSG00000110841       1726       1232       2145        819       2083
ENSG00000110844        195        142        226        100        254
ENSG00000110848          0          0          0          0          0
ENSG00000110851        689        634        711        464        722
ENSG00000110852        192        116        174        108        213
ENSG00000110871        395        296        486        282        422
ENSG00000110876         70         33        173         61        100
ENSG00000110880       6363       7257       9362       6028       7270
ENSG00000110881        332        258        434        173        283
ENSG00000110887          0          0          0          0          0
ENSG00000110888        539        413        863        350        824
ENSG00000110900        484        156        399         86        581
ENSG00000110906       2424       2951       3294       2646       2876
ENSG00000110911        894        937       1044        755       1074
ENSG00000110917       4427       3305       4769       2733       4386
ENSG00000110921        138         80        150         53         89
ENSG00000110925        597        519        561        383        722
ENSG00000110931       1092       1113       1198        851       1140
ENSG00000110934          0          0          0          0          0
ENSG00000110944         12         14         21         20         23
ENSG00000110955       6323       6377       7266       4646       7328
ENSG00000110958       2772       2478       3219       1918       3019
ENSG00000110975          0          0          0          0          0
ENSG00000110987        203        137        217        189        246
ENSG00000111011       1107       1071       1520        783       1667
ENSG00000111012          3         10          3          2          4
ENSG00000111046          0          0          0          1          1
ENSG00000111049          0          0          0          0          0
ENSG00000111052        318        254        523        318        660
ENSG00000111057          5          1          3          3         48
ENSG00000111058        670        497        746        526        950
ENSG00000111077       3625       3876       4073       2636       3465
ENSG00000111087         25         26         18          1         25
ENSG00000111110         39          6         29         10         18
ENSG00000111142       1618       1394       2008       1275       2204
ENSG00000111144       1279        948       1844        977       1583
ENSG00000111145       1787       1522       1641       1106       1796
ENSG00000111181          9          4          2          4          7
ENSG00000111186       1207        929       1557        881       1520
ENSG00000111196        138         98        145         39        130
ENSG00000111199         99        137        132         93        177
ENSG00000111203        303        188        436        165        368
ENSG00000111206        180        114        207         81        183
ENSG00000111215         33         20         53         29         48
ENSG00000111218          0          0          0          0          0
ENSG00000111224        299        185        345        162        305
ENSG00000111229       1444       1549       1980       1364       2247
ENSG00000111231        208        288        203        209        189
ENSG00000111237        889        865        900        700        857
ENSG00000111241          0          0          0          0          0
ENSG00000111245          0          0          0          0          0
ENSG00000111247         32         21         37         12         35
ENSG00000111249          0          0          0          0          0
ENSG00000111252        901        991       1281        927       1025
ENSG00000111254         35         18         46         13         27
ENSG00000111261        851        628       1199        646        585
ENSG00000111262          1          0          1          0          0
ENSG00000111266        449        301        530        278        498
ENSG00000111269       1876       1682       2247       1633       1839
ENSG00000111271        519        407        620        309        626
ENSG00000111275       1360       1760       1507       1027       1915
ENSG00000111276       1131        970       1198        630       1013
ENSG00000111291          1          2          3          3          1
ENSG00000111300        394        390        476        291        481
ENSG00000111305         12          6         49         26         41
ENSG00000111319          5          3         10          4          7
ENSG00000111321       2775       2965       3700       2426       3400
ENSG00000111325          7         10         11          2         22
ENSG00000111328       1696       1412       1431        797       1524
ENSG00000111331        224         91        268        122        241
ENSG00000111335         99         46        140         50        127
ENSG00000111339          0          0          0          0          0
ENSG00000111341        636        710       2555       3036       1534
ENSG00000111344          0          0          0          0          0
ENSG00000111348         10         19         25         16         13
ENSG00000111358        513        480        553        358        496
ENSG00000111361        782        748        899        541        966
ENSG00000111364        272        272        288        158        346
ENSG00000111371       1499       1853       2274       2399       1868
ENSG00000111404          0          0          0          1          0
ENSG00000111405          2         15          5          4          4
ENSG00000111412        455        406        487        378        566
ENSG00000111424       1065        756       1314        499       1152
ENSG00000111432          1          0          0          0          0
ENSG00000111445        162        134        162         86        178
ENSG00000111450        864       1099       1155       1027       1044
ENSG00000111452       6831       8906       9369       7332       4075
ENSG00000111481       2312       1690       2584       1270       2702
ENSG00000111490         33          3         37         11         17
ENSG00000111530       2979       2532       3512       2253       3445
ENSG00000111536          0          0          1          0          1
ENSG00000111537          0          0          0          0          0
ENSG00000111540        725        607        860        519        777
ENSG00000111554        178        162        238        131        275
ENSG00000111581        537        471        557        355        621
ENSG00000111596       1023        857       1141        651       1242
ENSG00000111602        192        124        243        105        271
ENSG00000111605       1291       1180       1388        887       1482
ENSG00000111615        451        323        502        261        478
ENSG00000111639       1051        965       1106        638        977
ENSG00000111640      30823      22361      35250      15386      31855
ENSG00000111641        349        429        383        262        444
ENSG00000111642       5307       3677       5799       2306       6894
ENSG00000111644          7          4         11          2         11
ENSG00000111647        764        594        818        464        890
ENSG00000111652       1994       1778       2177       1162       2055
ENSG00000111653        522        374        676        353        648
ENSG00000111664         45         40         53         21         47
ENSG00000111665         37         44         45         17         49
ENSG00000111666        911        872       1128        815        863
ENSG00000111667       1959       1540       2114       1049       1870
ENSG00000111669       7572       6294       8741       3535       8016
ENSG00000111670       2781       1713       5396       2494       3714
ENSG00000111671        163        125        159         72        156
ENSG00000111674       1907       1213       1326        493       1234
ENSG00000111676       4344       4957       5379       3239       6558
ENSG00000111678        248        277        227        138        200
ENSG00000111679          1          1          3          0          1
ENSG00000111684        513        680        719        550        717
ENSG00000111696        199        214        311        459        206
ENSG00000111700          0          0          0          0          0
ENSG00000111701          0          0          0          0          0
ENSG00000111704          2          1          0          0          2
ENSG00000111707        785        660        820        468        980
ENSG00000111711        904        734        777        539        898
ENSG00000111713          2          1          0          1          0
ENSG00000111716       6153       6097       6695       4283       6563
ENSG00000111725        448        432        529        367        561
ENSG00000111726        470        480        523        418        545
ENSG00000111727        689        569        768        406        845
ENSG00000111728        364        122        363         72        242
ENSG00000111729          6          2         10          1         10
ENSG00000111731        859        600        934        497        882
ENSG00000111732          1          2          0          0          0
ENSG00000111737       1088       1251       1107        829       1057
ENSG00000111752       1206        803       1102        460       1181
ENSG00000111775        322        321        349        216        336
ENSG00000111780          0          0          0          0          0
ENSG00000111783          0          0          0          0          1
ENSG00000111785        256        246        313        193        318
ENSG00000111786       1703       1744       1719       1226       1689
ENSG00000111788         94         61        132         34        147
ENSG00000111790        588        535        723        373        732
ENSG00000111796          0          0          1          0          1
ENSG00000111799      45063      32683      61416      27344      62577
ENSG00000111801        943        525       1251        476       1141
ENSG00000111802        668        625        629        470       1169
ENSG00000111816        140         47        114         29        136
ENSG00000111817       4262       3872       4658       3515       4857
ENSG00000111832        824        766       1032        663       1065
ENSG00000111834          8          1         15          4          9
ENSG00000111837          6          8         15          3         13
ENSG00000111843       1675       1503       1565       1153       1595
ENSG00000111845        199        172        204         92        277
ENSG00000111846         17         30         16         41         67
ENSG00000111850         63         62         77         41         52
ENSG00000111859        714       1256       1249       1988       1186
ENSG00000111860        436        354        469        249        514
ENSG00000111863         10          2          8          7          8
ENSG00000111875        307        242        276        173        355
ENSG00000111877        169        129        172         87        179
ENSG00000111879         15         10         11          3          8
ENSG00000111880        309        256        382        258        301
ENSG00000111885       4630       6677       4543       5212       4718
ENSG00000111886          8          8          5          2          1
ENSG00000111897       8977       9018      12430       9510      10715
ENSG00000111906        614        566        896        455        752
ENSG00000111907         97         54        516        251        147
ENSG00000111911        404        211        490        250        508
ENSG00000111912       1046       1381       1082       1242       1618
ENSG00000111913        113         34         61         26         68
ENSG00000111961       3017       3214       3504       1760       3977
ENSG00000111962        714        595        701        488        814
ENSG00000111971          0          0          0          0          0
ENSG00000111981         24         17         74         32         50
ENSG00000112029        111         77        129         37        108
ENSG00000112031        388        386        401        296        501
ENSG00000112033       1005        914       1107        701       1203
ENSG00000112038          0          0          0          0          0
ENSG00000112039        115        122        111         80        147
ENSG00000112041          0          2          8          5          1
ENSG00000112053          1          6          3          0          2
ENSG00000112062       1205       1220       1380        998       1289
ENSG00000112077          0          0          0          0          0
ENSG00000112078       2001       2137       2102       2076       2533
ENSG00000112079       1307       1327       1514       1100       1693
ENSG00000112081       2032       2004       2429       1446       1837
ENSG00000112096      11168      13633      12472      14681      22627
ENSG00000112110        637        650        757        431        666
ENSG00000112115          0          0          0          0          0
ENSG00000112116          0          0          0          0          0
ENSG00000112118        662        559        633        356        572
ENSG00000112130        319        399        435        282        423
ENSG00000112137         81         30         64         23         43
ENSG00000112139       1156        594       2185        765       1090
ENSG00000112144        660        626        773        444        816
ENSG00000112146       1200       1363       1506       1042       1423
ENSG00000112149        194        107        119         36         89
ENSG00000112159       1412       1233       1327        762       1494
ENSG00000112164          0          0          0          0          0
ENSG00000112167        337        289        270        196        257
ENSG00000112175          0          0          0          0          0
ENSG00000112182        128        132        133        100         31
ENSG00000112183         33          8         51         28         84
ENSG00000112186        271        165        541        251        484
ENSG00000112195          0          0          0          0          0
ENSG00000112200        668        564        852        472        822
ENSG00000112208       1822       1558       2500       1068       2020
ENSG00000112210       1124        985       2133        972       1797
ENSG00000112212          1          0          2          1          0
ENSG00000112214          0          1          0          0          0
ENSG00000112218         36         71         38         80         53
ENSG00000112232          0          0          0          0          0
ENSG00000112234        600        536        629        415        721
ENSG00000112237        579        494        659        479        608
ENSG00000112238          0          0          0          0          0
ENSG00000112242        291        262        390        229        430
ENSG00000112245       1680       1627       1651       1265       1936
ENSG00000112246          0          0          1          0          0
ENSG00000112249       2231       1657       2362       1017       2955
ENSG00000112273          0          0          0          0          0
ENSG00000112276        322        432        391        331        500
ENSG00000112280          0          0          0          0          0
ENSG00000112282        894        697        984        537       1044
ENSG00000112290        496        663        663        541        541
ENSG00000112293          1          1          2          1          7
ENSG00000112294          8          8         17          7         12
ENSG00000112297        303        327        224        249        341
ENSG00000112299          1          0          1          0          0
ENSG00000112303          2          2          3          0          7
ENSG00000112304        319        234        366        137        508
ENSG00000112305        176        108        220         93        225
ENSG00000112306      19630      18826      15981       8328      12135
ENSG00000112308       2594       1911       2980       1614       2683
ENSG00000112309          3          3          2          1          3
ENSG00000112312        138        124        107         63        188
ENSG00000112319        712        465        650        207        919
ENSG00000112320        381        216        431        162        459
ENSG00000112333          0          0          0          0          0
ENSG00000112335       3588       3318       4251       2548       4405
ENSG00000112337          0          1          0          0          0
ENSG00000112339       1064        923       1455        800       1440
ENSG00000112343       1017       1059       1108        818       1237
ENSG00000112357        103         74        137         67        121
ENSG00000112365        214        207        227        122        242
ENSG00000112367        512        380        705        353        552
ENSG00000112378       5726       4451       8337       5173       9461
ENSG00000112379         14         10         10          3          5
ENSG00000112394          2          6          1          0          1
ENSG00000112406        903        766        691        616        831
ENSG00000112414       1004       1186        639        629        371
ENSG00000112419       1195       1028       1760       1415       1487
ENSG00000112425        118        121        117         87        134
ENSG00000112459          0          0          0          0          0
ENSG00000112461          0          0          0          0          0
ENSG00000112462          0          0          0          0          0
ENSG00000112473       3364       2738       3878       1847       4035
ENSG00000112474          0          0          0          0          0
ENSG00000112486          0          0          0          0          0
ENSG00000112493          0          0          0          0          0
ENSG00000112494          0          0          0          0          0
ENSG00000112499          0          1          0          0          0
ENSG00000112511       1491       1183       1444        812       1537
ENSG00000112514       1295       1094       1520        680       1577
ENSG00000112530          3          4          3          2          2
ENSG00000112531       2727       2859       2943       2171       3425
ENSG00000112539          0          0          0          0          0
ENSG00000112541         17         21          2          1         50
ENSG00000112559         14          3          1          2          0
ENSG00000112561        101         62         74         30        115
ENSG00000112562          2          2          4          6          0
ENSG00000112576        494        708        491        617        470
ENSG00000112578        170        167        184         95        229
ENSG00000112584       1104        907       1326        707       1388
ENSG00000112592        201        178        280        144        283
ENSG00000112599          5          2          9          4         17
ENSG00000112619        217        149        200         67        209
ENSG00000112624        524        407        622        368        605
ENSG00000112640       1185       1092       1354        787       1290
ENSG00000112651        238        189        234        130        265
ENSG00000112655       8598       6388       9993       5139       8582
ENSG00000112658        963       1661       1099        965        976
ENSG00000112659        829        614        838        332        790
ENSG00000112667        191        169        194         91        169
ENSG00000112679        727        744        699        551        669
ENSG00000112685       1038        853        875        542       1173
ENSG00000112695        784        805        819        574        459
ENSG00000112697       7801       6106       6423       4278       6078
ENSG00000112699        475        299        382        172        450
ENSG00000112701       1612       1338       1852       1129       2169
ENSG00000112706         13          9         10         10          9
ENSG00000112715       3144       1126       2949        476       2835
ENSG00000112739       1561       1580       1775       1050       2006
ENSG00000112742         27         24         27          6         16
ENSG00000112759        643        448        931        505        809
ENSG00000112761          0          0          4          1          5
ENSG00000112763        484        478        689        415        667
ENSG00000112769      18104      15138      23501      11363      22027
ENSG00000112773        779        299        828        186        911
ENSG00000112782          0          0          0          0          0
ENSG00000112787        523        533        471        341        507
ENSG00000112796         65         33         56         22         19
ENSG00000112799          0          0          0          0          0
ENSG00000112812          1          0          1          0          0
ENSG00000112818          0          0          0          0          0
ENSG00000112837       4230       1103       4313        658       5631
ENSG00000112851       2354       2511       2690       2197       2940
ENSG00000112852        182        149        218        112        129
ENSG00000112855        461        387        477        284        462
ENSG00000112874        308        263        379        242        325
ENSG00000112877         23         13         27          5         25
ENSG00000112893       2039       1875       2294       1393       2280
ENSG00000112902       4299       2697       3067       1134       7599
ENSG00000112936        256       4900        293        914        943
ENSG00000112941        542        452        525        344        548
ENSG00000112964        158        139        127         81         53
ENSG00000112972        285        172        339        152        309
ENSG00000112977       3986       3190       4985       2724       4448
ENSG00000112981         20         17         62         32         52
ENSG00000112983       1377       1035       1756        897       1803
ENSG00000112984         38         53         46         32         43
ENSG00000112992       1736       1447       1704       1039       2174
ENSG00000112996        534        424        529        316        648
ENSG00000113013       3235       2683       3688       1881       4371
ENSG00000113048       1152        970       1327        711       1394
ENSG00000113068        740        619        785        460        737
ENSG00000113070         15          7         16          6         14
ENSG00000113073          0          0          1          0          0
ENSG00000113083       8448       9235      16171      13695       9872
ENSG00000113088          0          0          0          0          0
ENSG00000113100          0          0          0          0          0
ENSG00000113108        380        336        430        262        368
ENSG00000113119        128        152        130        123        123
ENSG00000113140      35440      24777      41733      16058      41296
ENSG00000113141       1790       1757       2059       1302       2289
ENSG00000113161        400        290        507        252        400
ENSG00000113163       1669       1993       1664       1473       1470
ENSG00000113194       1610       1379       1853       1149       2022
ENSG00000113196          0          1          0          0          0
ENSG00000113205         40         29         53         15         16
ENSG00000113209         59         24         68         27         20
ENSG00000113211         20         23         15         10         14
ENSG00000113212        104         69         76         33         53
ENSG00000113231         26         34         44         28         51
ENSG00000113240        566        564        641        415        651
ENSG00000113248         34         18         25         10         33
ENSG00000113249          0          0          0          0          2
ENSG00000113262          3          0          7          2          1
ENSG00000113263          0          1          0          0          0
ENSG00000113269       1409       1146       1740       1002        957
ENSG00000113272        184        142        212        125        206
ENSG00000113273       1422       1195       1658       1118       2398
ENSG00000113282       1662       1402       1676       1126       1883
ENSG00000113296         33         29         64         28         43
ENSG00000113300        613        457        684        380        775
ENSG00000113302          0          0          0          0          0
ENSG00000113303          1          0          0          0          0
ENSG00000113312        699        644        866        528        765
ENSG00000113318        427        316        399        190        450
ENSG00000113319        444        276        401        139        956
ENSG00000113327          0          0          0          0          0
ENSG00000113328       5652       3814       5671       3382       6204
ENSG00000113356        110        116        189         85        218
ENSG00000113360       1246       1039       1485        934       1325
ENSG00000113361       1327        483       5505       1208       2215
ENSG00000113368         79         57         66         11         83
ENSG00000113369       1151        533       1360        734       1214
ENSG00000113384       2898       3141       3007       2236       3016
ENSG00000113387       2613       2050       2422       1302       2929
ENSG00000113389        929       1688       2099       1816       2749
ENSG00000113391       1003        777       1113        738       1054
ENSG00000113396          6         15          3          1          9
ENSG00000113407       1372       1137       2010        814       2017
ENSG00000113430          0          0          0          0          0
ENSG00000113441        913       1055        916        764        878
ENSG00000113448        323        544        170         73        621
ENSG00000113456        667       1012        856        838        799
ENSG00000113460        222        387        336        395        350
ENSG00000113492          0          0          0          0          0
ENSG00000113494          0          1          2          2          0
ENSG00000113504        695        568        509        319        577
ENSG00000113520          2          1          0          0          0
ENSG00000113522       1500       1417       1776        956       2120
ENSG00000113525          1          0          2          0          3
ENSG00000113532          0          0          0          0          0
ENSG00000113552       2280       1249       1811        874       2148
ENSG00000113555         16         18         27         16         34
ENSG00000113558       3046       2912       3745       2339       3695
ENSG00000113569        547        369        496        305        515
ENSG00000113575       1356       1237       1453        961       1554
ENSG00000113578         58        106        247        214        119
ENSG00000113580       4275       1655       4347       1274       3224
ENSG00000113583       1584       1371       1779       1228       1691
ENSG00000113593        622        528        730        426        676
ENSG00000113594        559        611        622        533        608
ENSG00000113595        423        355        474        342        457
ENSG00000113597        243        187        359        171        328
ENSG00000113600          1          7          4          4          8
ENSG00000113615       1010        928        964        638       1147
ENSG00000113621       1081       1153       1229        833       1353
ENSG00000113638        195        155        216        126        209
ENSG00000113643       1369       1209       1639        957       1840
ENSG00000113645         66        127         88         63        144
ENSG00000113648       1602       1351       1545        880       2060
ENSG00000113649        859        704       1004        494       1087
ENSG00000113657       6165       3728       7137       2188       6835
ENSG00000113658       2381       1630       2110       1246       2291
ENSG00000113712       2792       2324       3277       1510       3359
ENSG00000113716        953        847       1150        751       1272
ENSG00000113719       4666       6634       7064       6220       5726
ENSG00000113721      17725      18484      21210      16640      22011
ENSG00000113722         16          8         23          7         14
ENSG00000113732       3463       3879       3686       2692       3977
ENSG00000113734        123         98        183         70        146
ENSG00000113739      12219      12721       8738      16519       6556
ENSG00000113742        555        455        560        367        739
ENSG00000113749          0          1          0          0         11
ENSG00000113758       3378       2881       4614       1899       4730
ENSG00000113761        251        225        333        180        313
ENSG00000113763          0          1          0          1          0
ENSG00000113790        120        121        200        127        116
ENSG00000113805        371        240        748        407        494
ENSG00000113810        783        534        874        373        979
ENSG00000113811        364        348        379        276        429
ENSG00000113812        726        554        773        363        659
ENSG00000113838        144        124        172        112        147
ENSG00000113845       1121       1133       1184        836       1311
ENSG00000113851        557        453        629        396        651
ENSG00000113889          0          0          0          0          0
ENSG00000113905          0          0          0          1          1
ENSG00000113916       1265       1787       1564       1546       1413
ENSG00000113924          1          1          1          0          3
ENSG00000113946          0          1          1          0          0
ENSG00000113966         91         62        122         55        118
ENSG00000113971        618        471       1123        674       1038
ENSG00000114013          0          0          0          0          0
ENSG00000114019       2093       3187       3401       3072       2829
ENSG00000114021        489        651        580        493        639
ENSG00000114023        763        529        944        391        866
ENSG00000114026        329        265        381        143        343
ENSG00000114030        785        803        909        608       1037
ENSG00000114054        380        240        522        261        548
ENSG00000114062       1242       1182       1433        914       1697
ENSG00000114098        600       1381        647        889        675
ENSG00000114107        217        214        294        216        271
ENSG00000114113          1          1          3          1          2
ENSG00000114115         42         21         33          1         14
ENSG00000114120       1906       1922       2148       1356       2241
ENSG00000114124          2          1          0          3          0
ENSG00000114125        671        737        731        520        765
ENSG00000114126       1111        774       1214        583       1229
ENSG00000114127       1477       1200       1713       1103       1735
ENSG00000114166        664        524        914        547        625
ENSG00000114200         46         39         74         22         14
ENSG00000114204          0          0          0          0          0
ENSG00000114209        389        492        475        386        480
ENSG00000114248          0          0          0          0          1
ENSG00000114251       4262       2516       5412       1829       9344
ENSG00000114268        152         79        123         48        169
ENSG00000114270       1208       2327        917       1159       1130
ENSG00000114279          0          1          0          1          1
ENSG00000114302       1079       1065       1174        758       1325
ENSG00000114315          1          0          1          0          0
ENSG00000114316       1217        987       1517       1042       1620
ENSG00000114331       2173       1547       2409       1312       2940
ENSG00000114346        381        393        455        269        468
ENSG00000114349          0          0          0          0          0
ENSG00000114353       7065       6171       8318       4392       7984
ENSG00000114354       1951       1743       2422       1449       2560
ENSG00000114374       1358       1166       1587        907       1569
ENSG00000114378         20         25         36         11         18
ENSG00000114383        351        338        351        249        337
ENSG00000114388        268        226        277        134        307
ENSG00000114391       7685       7116       7401       4034       7115
ENSG00000114395        109         84        129         59        123
ENSG00000114405        143        144         97         75        112
ENSG00000114416       2864       2432       3553       2128       3960
ENSG00000114423        594        682        553        478        699
ENSG00000114439       2043       2015       2502       1664       2761
ENSG00000114446        764        665       1010        574        965
ENSG00000114450        881       1180        724        905        842
ENSG00000114455          0          0          0          0          1
ENSG00000114473        207        207        284        140        266
ENSG00000114480       3934       4225       1793       1521       4574
ENSG00000114487          0          0          0          0          0
ENSG00000114491        285        261        315        172        297
ENSG00000114503       1444       1234       1562        897       1784
ENSG00000114520        382        347        382        291        412
ENSG00000114529         25         16         17         11         39
ENSG00000114541          3          1          3          2          0
ENSG00000114544        908        682        986        606       1169
ENSG00000114547          1          0          1          0          1
ENSG00000114554       2950       2266       3689       1812       2083
ENSG00000114573       2216       1649       2092       1211       3689
ENSG00000114626        893       1086       1016        801        820
ENSG00000114631         43         34         39         11         33
ENSG00000114638          0          0          0          0          0
ENSG00000114646          5          0          5          1          2
ENSG00000114648        357        307        446        235        497
ENSG00000114650       1470       1652       1628       1113       1686
ENSG00000114654          1          0          1          0          0
ENSG00000114656          0          1          0          0          0
ENSG00000114670        276        106        269         57        263
ENSG00000114686        838        762        924        501       1015
ENSG00000114698       1665       1939       2308       1882       2124
ENSG00000114735        446        250        499        170        457
ENSG00000114737         62         43         51         33         59
ENSG00000114738        581        496        711        338        803
ENSG00000114739        117         74        101         74        131
ENSG00000114742       1197       1018       1447        876       1475
ENSG00000114744        462        500        572        376        659
ENSG00000114745        849       1083        958        759        930
ENSG00000114757          7          4         10          7         11
ENSG00000114767        163        304        148        175        180
ENSG00000114770       1030        912       1073        842       1313
ENSG00000114771          3          3          3          4          2
ENSG00000114779        874        893        885        545        769
ENSG00000114784        524        471        672        397        707
ENSG00000114786          0          0          2          0          0
ENSG00000114790         45         45         43         48         66
ENSG00000114796       1323       1014       1157       1102       1319
ENSG00000114805          0          1          5          2          4
ENSG00000114812          0          0          0          0          0
ENSG00000114841        314        231        427        142        235
ENSG00000114850       2681       2820       3112       2470       2673
ENSG00000114853       2647       4207       2728       2580       2929
ENSG00000114854          4          3          4          2          1
ENSG00000114857       1542       1193       1881        866       2384
ENSG00000114859         66         63         79         29         68
ENSG00000114861       1830       1297       2285       1070       2249
ENSG00000114867       7251       7499       8724       5221       9167
ENSG00000114902       1192       1067       1328        908       1328
ENSG00000114904        429        314        408        235        497
ENSG00000114923        139         96        149         86        321
ENSG00000114933        293        298        395        251        359
ENSG00000114942       6305       6311       6888       3419       6569
ENSG00000114948         91        138       1078        823        252
ENSG00000114956        313        314        366        215        350
ENSG00000114978       2665       2677       2871       2411       3041
ENSG00000114982       1881       1925       2338       1798       2098
ENSG00000114988        488        409        577        380        403
ENSG00000114993        300        238        304        124        292
ENSG00000114999       1290       1154       1447        955       1365
ENSG00000115008          0          0          1          0          1
ENSG00000115009          0          4          0          0          2
ENSG00000115020       1181       1090       1401        963       1526
ENSG00000115041        183        172        127         84        135
ENSG00000115042        428        328        477        241        460
ENSG00000115053       8601       7840      10676       5634      11676
ENSG00000115073        830        768       1055        546        868
ENSG00000115084       1253       1368       1480       1565       1553
ENSG00000115085          0          0          2          1          2
ENSG00000115091       3033       3877       3400       2900       3462
ENSG00000115107        169         74        276        123        620
ENSG00000115109        629        651        694        511        955
ENSG00000115112          0          1          0          0          0
ENSG00000115128        648        547        857        453        900
ENSG00000115129        728        531        758        407        842
ENSG00000115137        120        104        180         74        172
ENSG00000115138          3          5          3          0          3
ENSG00000115145        940        795        965        674       1137
ENSG00000115155          1          2          1          1          0
ENSG00000115159        536        780        502        452        984
ENSG00000115163          6         11         10          6          5
ENSG00000115165          0          0          0          0          2
ENSG00000115170       1744       1497       1695       1066       1872
ENSG00000115183       1660       1030       1383        534       1628
ENSG00000115194          6          8          6          4          4
ENSG00000115204       1204       1022       1285        713       1267
ENSG00000115207        601        528        599        366        663
ENSG00000115211        516        527        547        340        570
ENSG00000115216       2139       2093       2556       1457       2627
ENSG00000115221          1          4          4          0          0
ENSG00000115226        511        468        522        320        602
ENSG00000115232       3580       3175       1454       1226       1466
ENSG00000115233        699        738        827        557        848
ENSG00000115234       2195       1985       2273       1376       2252
ENSG00000115239         15          9         15          8         10
ENSG00000115241       1260       1213       1402        794       1554
ENSG00000115252        139        225        612        437        276
ENSG00000115255         49         64         61         39         49
ENSG00000115257         64         67         80         24         74
ENSG00000115263          0          1          0          1          0
ENSG00000115266         92         98        110         54        100
ENSG00000115267        274        149        258        132        282
ENSG00000115268       5265       4715       5492       2622       5200
ENSG00000115271        105        105         98        107        104
ENSG00000115274        343        287        402        164        324
ENSG00000115275        918        888        856        554        774
ENSG00000115282        410        321        467        229        456
ENSG00000115286        393        300        376        155        375
ENSG00000115289        191        192        246        108        269
ENSG00000115290         29         19         62         54         25
ENSG00000115295       1429       1327       1618       1529       1913
ENSG00000115297          0          1          0          0          0
ENSG00000115306      10657      10887      15588       8916      12259
ENSG00000115307       1108       1399       1283        812       1253
ENSG00000115310      13633      12798      20244      13519      18327
ENSG00000115317        240        197        227        138        250
ENSG00000115318        449        342        525        225        681
ENSG00000115325        316        345        385        215        403
ENSG00000115339         22         23         26         17         22
ENSG00000115350        253        214        292        175        286
ENSG00000115353          1          0          0          0          0
ENSG00000115355       1132        828       1470        648       1734
ENSG00000115361         12         17         21         20         10
ENSG00000115363         68         52        137         47        100
ENSG00000115364        448        402        555        290        553
ENSG00000115365       1560       1216       1706       1264       1593
ENSG00000115368        575        608        635        401        810
ENSG00000115380      15615      13920      36640      19472      28017
ENSG00000115386          0          0          0          0          0
ENSG00000115392        121         76        155         81        178
ENSG00000115414     260262     213986     513766     273878     252667
ENSG00000115415       5992       5920       6990       4632      10470
ENSG00000115419       2217       4220       2498       4022       2587
ENSG00000115421        344        301        388        263        388
ENSG00000115423         13          6          7          4         12
ENSG00000115425        121        107        139         68        127
ENSG00000115446        656        658        757        474        674
ENSG00000115457        115        483       1758       2745        985
ENSG00000115459        376        360        478        234        472
ENSG00000115461      74051      79611     328753     137165     241640
ENSG00000115464       2705       2148       3256       1735       3615
ENSG00000115468          0          0          0          5         19
ENSG00000115474          0          0          0          0          1
ENSG00000115484       1790       1563       1909       1080       2026
ENSG00000115486       1127        678       1293        588       1356
ENSG00000115488          0          0          0          0          0
ENSG00000115504       4278       3268       6005       2758       4933
ENSG00000115507          6          8         83         28          2
ENSG00000115514        350        362        407        300        365
ENSG00000115520        493        418        617        389        573
ENSG00000115523          1          0          0          0          1
ENSG00000115524       7726       5848       9966       5040       9664
ENSG00000115525        317        292        456        268        518
ENSG00000115526        175        149        225        112        148
ENSG00000115539        105        142        133         89        131
ENSG00000115540        286        282        336        225        332
ENSG00000115541        140        117        106         91         83
ENSG00000115548       1375       1311       1081        868       1422
ENSG00000115556        133        103        193         79        222
ENSG00000115561       1975       1600       2069       1319       1705
ENSG00000115568        474        403        553        241        563
ENSG00000115590          1          2          2          3          5
ENSG00000115592          2          1          5          0          2
ENSG00000115593          0          0          0          0          0
ENSG00000115594      11544      11742      10391       8182      15754
ENSG00000115596          0          0          0          0          0
ENSG00000115598         32         19         27         13         35
ENSG00000115602          0          6          0          0          1
ENSG00000115604         55         39         23          8         47
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ENSG00000115616          0          0          0          0          1
ENSG00000115641       4223       4482       5878       3620       4388
ENSG00000115648         63         26        102         42        188
ENSG00000115649        920        864        922        678        696
ENSG00000115652        523        583        809        519        715
ENSG00000115657         33         38         23         17         25
ENSG00000115661        476        474        608        380        526
ENSG00000115665          0          0          1          0          0
ENSG00000115677      23536      18274      26848      13579      26452
ENSG00000115685        987        816       1141        588       1040
ENSG00000115687         55         75         79         39         67
ENSG00000115694       1641       1545       1672        906       1666
ENSG00000115705          0          0          0          0          0
ENSG00000115718          1          1          1          0          1
ENSG00000115738       1567       1595       1760        944       1114
ENSG00000115750        327        282        373        212        462
ENSG00000115756        271        262        303        183        317
ENSG00000115758        392        469        574        290        518
ENSG00000115760       2976       2761       3095       2085       3458
ENSG00000115761        415        389        400        215        409
ENSG00000115762       1263       1249       1735       1069       1711
ENSG00000115806       2118       1728       2454       1196       2694
ENSG00000115808        785        733        893        572        852
ENSG00000115816        518        513        540        350        645
ENSG00000115825       1861       1736       2033       1091       2223
ENSG00000115827        365        363        476        265        499
ENSG00000115828        135        385        209        314        381
ENSG00000115839       2581       2206       3179       1730       2920
ENSG00000115840        426        532        402        428        496
ENSG00000115841        132        203        159        156        184
ENSG00000115844          0          0          0          2          2
ENSG00000115850          0          0          0          1          0
ENSG00000115866       1638       1311       1687       1008       1520
ENSG00000115875        821        715       1087        519        870
ENSG00000115884        465        240        654        204        757
ENSG00000115896        387        583        404        304        432
ENSG00000115902        140        106        215        112        121
ENSG00000115904       2894       2721       3560       2689       4373
ENSG00000115919         14         12          3          2         13
ENSG00000115934          0          0          0          0          0
ENSG00000115935       1327       1443       1635       1126       1655
ENSG00000115942        290        250        330        204        346
ENSG00000115944       1710       1489       1648        913       1683
ENSG00000115946        112        194        149        142        201
ENSG00000115947        352        336        379        241        397
ENSG00000115956          0          1          4          0          2
ENSG00000115963      22716       9045      22098       9914      26285
ENSG00000115966        958        841       1089        693       1031
ENSG00000115970        655        526        710        432        769
ENSG00000115977        287        235        396        145        360
ENSG00000115993       3088       4059       4163       5194       4396
ENSG00000115998        215        144        254        113        252
ENSG00000116001       1587       1003       1831        742       1906
ENSG00000116005       5637       6564       9760       7819       9103
ENSG00000116014          0          0          0          0          0
ENSG00000116016      26544      12781      29614       9911      35744
ENSG00000116017        436        542        360        229        527
ENSG00000116030       1651       1283       1787       1121       1965
ENSG00000116031          0          0          1          0          0
ENSG00000116032         41         39         80         31         59
ENSG00000116035          8         18         11         10         16
ENSG00000116039         14         21         22         10          8
ENSG00000116044       6035       5864       6669       4657       9462
ENSG00000116062       1008        919       1079        684       1166
ENSG00000116095        304        397        445        355        454
ENSG00000116096        305        337        381        261        315
ENSG00000116106        145        433        147        125        191
ENSG00000116117       1431       1379       2702       1912       2150
ENSG00000116120        446        435        551        289        480
ENSG00000116127        408        250        509        182        515
ENSG00000116128        622        401        690        261        573
ENSG00000116132       7253       4073       8600       2920       8539
ENSG00000116133       4242       7675       5673       4687       3836
ENSG00000116138        579        530        609        448        667
ENSG00000116141         54        129         24         27          7
ENSG00000116147          0          0          0          0          0
ENSG00000116151         40         43         44         20         45
ENSG00000116157        139        117        309        155        411
ENSG00000116161        829        570        881        471        872
ENSG00000116171       3455       2531       3836       1958       3807
ENSG00000116176          0          0          1          0          0
ENSG00000116183        158        159         68         20         22
ENSG00000116191       1979       1541       2285       1017       3544
ENSG00000116194         73        401        154        285         62
ENSG00000116198        516        592        571        377        769
ENSG00000116199       1512       1482       2253       1629       1894
ENSG00000116205        262        239        355        170        291
ENSG00000116209       3812       3624       4946       3351       4362
ENSG00000116212        514        547        586        461        648
ENSG00000116213        317        325        322        219        368
ENSG00000116218          0          0          0          0          0
ENSG00000116221        863        763       1040        566       1134
ENSG00000116237       2600       2407       3051       1873       2894
ENSG00000116251       9464       8419      10405       5863       9550
ENSG00000116254          9         10         16          9          5
ENSG00000116260     235670     204991     240239     119073     223381
ENSG00000116266        858        848        931        668        930
ENSG00000116273        641        625        613        485        667
ENSG00000116285        835       3133       1290       4344       1506
ENSG00000116288       2504       2467       2580       1498       2549
ENSG00000116299         46         22         32         12         66
ENSG00000116329          0          0          0          0          0
ENSG00000116337        925        753        969        408       1041
ENSG00000116350       1399       1473       1492        967       1849
ENSG00000116353        243        226        296        117        296
ENSG00000116396         90         71         96         57         93
ENSG00000116406       1405       1564       1625       1361       1811
ENSG00000116455        236        270        227        183        251
ENSG00000116459       1967       1676       2092       1264       2087
ENSG00000116473        989        927       1059        754       1135
ENSG00000116478       1354       1096       1666       1166       1736
ENSG00000116489       2932       2883       3590       2209       3694
ENSG00000116497        612        603        653        439        730
ENSG00000116514        197        151        250        115        265
ENSG00000116521        999       1083       1212        705       1315
ENSG00000116525        169        165        189        112        232
ENSG00000116539       2534       1903       2779       1493       3068
ENSG00000116544          2          2          2          0          3
ENSG00000116560       3628       3710       3168       2327       3937
ENSG00000116574        379        427        450        166         57
ENSG00000116580       1047        850       1386        644       1416
ENSG00000116584       3189       1411       3637        942       3365
ENSG00000116586        390        338        474        261        523
ENSG00000116604       1534       1734       1625       1200       1680
ENSG00000116641       2848       2344       3146       1686       3655
ENSG00000116649       1004       1255       1122       1313       1100
ENSG00000116652          7          4          9          3         10
ENSG00000116661         24         37         57         30         43
ENSG00000116663        114        120        135         78        113
ENSG00000116667       2033       3630       2932       2860       1411
ENSG00000116668        176        124        217        124        216
ENSG00000116670        341        386        354        235        369
ENSG00000116675          7         41         37         67         28
ENSG00000116678        595        481        646        766       1313
ENSG00000116679        759        420       1218        328       1187
ENSG00000116685       1244       1109       1341        818       1243
ENSG00000116688       3018       2373       3386       1735       3317
ENSG00000116690          1         32         15         16         23
ENSG00000116691        231        291        194        131        204
ENSG00000116698        993        832       1241        620       1402
ENSG00000116701          1          0          3          2          7
ENSG00000116703          0          0          3          0          1
ENSG00000116704        478        746        546        526        548
ENSG00000116711        172         30        148         26        147
ENSG00000116717       1360       1584       1576       1128       2168
ENSG00000116721          0         11          0          0          0
ENSG00000116726          1          4          0          0          0
ENSG00000116729       3750       2548       4165       1993       5890
ENSG00000116731       1115       1178       1408        900       1202
ENSG00000116741        135        200        248         78        300
ENSG00000116745          0          0          0          0          0
ENSG00000116747        671        700        774        586        871
ENSG00000116748          0          0          0          0          0
ENSG00000116750        313        286        352        217        344
ENSG00000116752        394        322        408        221        481
ENSG00000116754       4501       4366       4710       3278       5119
ENSG00000116761         47         72         41         43         34
ENSG00000116771          4         12          6          5         16
ENSG00000116774       3773       3746       4584       2761       3823
ENSG00000116783          2          1          0          1          0
ENSG00000116785          2          1          6          4          5
ENSG00000116786       3293       3065       3502       2283       3814
ENSG00000116791        512        336        492        272        580
ENSG00000116793        501        431        505        422        676
ENSG00000116809        487        384        471        236        460
ENSG00000116815         73         52         79         55         65
ENSG00000116819         20          8         15          6         28
ENSG00000116824          1          0          0          1          0
ENSG00000116830        336        250        265        118        337
ENSG00000116833          0          0          0          0          0
ENSG00000116852          0          1          0          1          0
ENSG00000116857       1151        785       1112        473        903
ENSG00000116863        396        366        396        233        417
ENSG00000116871       2964       3113       3478       1842       3785
ENSG00000116874        286        236        444        263        341
ENSG00000116882          1          0          1          0          1
ENSG00000116883        104        103        170         95         53
ENSG00000116885        102         74        181         81        140
ENSG00000116898        634        620        733        363        799
ENSG00000116903        341        312        360        233        350
ENSG00000116906        973        917        965        663        960
ENSG00000116918        494        500        584        460        531
ENSG00000116922        297        283        352        216        342
ENSG00000116954       1424       1566       1400       1105       1535
ENSG00000116957        391        335        557        304        470
ENSG00000116962       4884      16444       5558       8983       5005
ENSG00000116977        850        728       1015        563       1140
ENSG00000116981          0          0          0          0          0
ENSG00000116983          0          0          0          0          1
ENSG00000116984       1669       1320       1619       1047       2490
ENSG00000116985          8         10         12          8          4
ENSG00000116990          2          4          9          1          6
ENSG00000116991        349         38        232         16         50
ENSG00000116996          0          0          0          0          0
ENSG00000117000        698        554        594        380        681
ENSG00000117009          2          2          2          0          4
ENSG00000117010         61         45         69         42         75
ENSG00000117013          1          4          2          6          6
ENSG00000117016        123        117         88         46         25
ENSG00000117020        983        974       1174        943       1350
ENSG00000117036        575        484        569        379        601
ENSG00000117054        455        405        495        388        389
ENSG00000117069         15          7         22         16         11
ENSG00000117090          0          0          0          0          0
ENSG00000117091          0          0          0          0          0
ENSG00000117114       2849       2283       2975       1237       1451
ENSG00000117115          0          1         13          3          6
ENSG00000117118        656        660        865        557        996
ENSG00000117122        788        439        900        378       1002
ENSG00000117133        379        324        379        259        468
ENSG00000117139       2197       1574       2123       1139       2746
ENSG00000117143       1201       1715       1598       1353       1432
ENSG00000117148          2          2          0          0         42
ENSG00000117151        423        356        554        394        445
ENSG00000117152        103         47        270         65         97
ENSG00000117153        883        758       1010        544        957
ENSG00000117154          0          0          0          0          0
ENSG00000117155        521        498        916        379        547
ENSG00000117174        573        570        753        473        923
ENSG00000117215          0          0          0          0          0
ENSG00000117222        577        418        727        300        640
ENSG00000117226        150         84        202         63       1562
ENSG00000117228        975       1337       1395        820        988
ENSG00000117242        103         90        114         76         90
ENSG00000117245         12         13         42         29         80
ENSG00000117262        549        463        548        359        691
ENSG00000117266        246         88         60         19        101
ENSG00000117280        894       1203       1046        964       1214
ENSG00000117281         14         15         17          9         32
ENSG00000117289      17037      12119      22102      13412      12467
ENSG00000117298       6981       7809       7821       5093       8317
ENSG00000117305        678        522        799        451        811
ENSG00000117308        122         97        118         37         85
ENSG00000117318        116        127        118         45        167
ENSG00000117322          0          0          0          0          0
ENSG00000117335       4283       3808       6296       3558       6559
ENSG00000117360        528        520        631        377        750
ENSG00000117362       2015       1686       2056       1426       1795
ENSG00000117385       1748       1212       2062        849       1599
ENSG00000117394       2092       2144       3164       1525       2520
ENSG00000117395        458        432        557        323        642
ENSG00000117399         41         43         35         17         29
ENSG00000117400          0          0          2          2          0
ENSG00000117407          4          5          3          2         10
ENSG00000117408        753        810        900        496        857
ENSG00000117410        677        756        573        470        616
ENSG00000117411       1273        925       1395        591       1370
ENSG00000117419        680        669        850        496        779
ENSG00000117425         24         27         54         29         88
ENSG00000117448        994        752       1040        536        824
ENSG00000117450       3737       3668       5343       3019       4693
ENSG00000117461        215         72        487        102        520
ENSG00000117472          1          0         11          1         16
ENSG00000117475        415        409        589        351        630
ENSG00000117477         15          5          6          5         14
ENSG00000117479        172        390        145        199        201
ENSG00000117480         21         34         23         21         30
ENSG00000117481        277        250        323        177        336
ENSG00000117500       1672       1902       1736       1435       2217
ENSG00000117501          0          0          0          0          0
ENSG00000117505       1129       1006       1123        712       1081
ENSG00000117507          2          4         11          4          3
ENSG00000117519       4390       6345       7214       5402       5485
ENSG00000117523       5166       3686       6982       3426       7045
ENSG00000117525        344        454        390        264        803
ENSG00000117528       1136        877       1066        660       1340
ENSG00000117533       1267       1117       1493       1098       1352
ENSG00000117543        260        202        273        130        277
ENSG00000117560          0          0          0          0          0
ENSG00000117569        301        231        379        194        394
ENSG00000117586         41         49         39         28         40
ENSG00000117592       2989       3940       3698       2849       3788
ENSG00000117593        309        282        341        217        360
ENSG00000117594        173       1137        453        448       1454
ENSG00000117595         12         11        106         74         14
ENSG00000117597        577        497        657        493        635
ENSG00000117598          1          0          4          0          3
ENSG00000117600         57          9         68          7        110
ENSG00000117601          2          4          0          1          2
ENSG00000117602        147        226        336        353        197
ENSG00000117614       1067       1079       1193        804       1457
ENSG00000117616       1448       1644       1445       1042       1796
ENSG00000117620        433        388        513        386        476
ENSG00000117625        751        603        948        542        929
ENSG00000117632       1019       1020       1310        834       1885
ENSG00000117640        779        720        943        493        853
ENSG00000117643       1190        701       1793        685        867
ENSG00000117650         15         15          7          4          7
ENSG00000117676          5          8         14          8         27
ENSG00000117682        651        578        845        519        857
ENSG00000117691        864        673        811        514        774
ENSG00000117697        434        295        483        220        497
ENSG00000117707          7          4          7          7         10
ENSG00000117713       1669       1291       1899       1044       2002
ENSG00000117724        166        105        165         78        167
ENSG00000117748        436        304        867        472        831
ENSG00000117751        618        585        722        447        721
ENSG00000117758       1124       1667       1472       1842       1385
ENSG00000117791        232        239        329        279        291
ENSG00000117834         15         23         18          9         18
ENSG00000117859       1249       1805       1651       1288       1616
ENSG00000117862       1002        928       1171        811       1274
ENSG00000117868       3768       4545       5449       4465       4159
ENSG00000117877         17         17         21         11         29
ENSG00000117899       1330       1437       1716       1165       1618
ENSG00000117906       1291       1414       1983       1424       2037
ENSG00000117971          0          0          0          0          0
ENSG00000117983          1          1          0          0          0
ENSG00000117984       3340       2809       3930       2298       4448
ENSG00000118004          0          1          2          0          1
ENSG00000118007       1511       1219       1383        831       1781
ENSG00000118017          3          6         12          5          0
ENSG00000118046       1213       1029       1266        649       1297
ENSG00000118058       3215       2005       3108       1451       3336
ENSG00000118094          1         10          4          2          1
ENSG00000118096        430        340        585        274        480
ENSG00000118113          0          0          6          2          1
ENSG00000118137          0          1          0          0          1
ENSG00000118156          8          4         12          2          1
ENSG00000118160          0          2          1          2          2
ENSG00000118162        206        206        177        111        181
ENSG00000118181       9116       8803       9462       4810       8770
ENSG00000118193         23         20         16         10         18
ENSG00000118194          0          1          1         18          0
ENSG00000118197        203        209        249        183        261
ENSG00000118200       1577       1425       1720       1190       2130
ENSG00000118217       1142        975       1609       1063       1579
ENSG00000118231          0          0          0          0          0
ENSG00000118242         58         23         44         21         45
ENSG00000118245          0          0          0          0          0
ENSG00000118246        472        391        544        317        525
ENSG00000118257       1414       1914       1321       1604       1380
ENSG00000118260        924        621        984        408       1033
ENSG00000118263        539        445        697        431        461
ENSG00000118271          0          0          0          0          0
ENSG00000118276         68         56         58         37         20
ENSG00000118292        127         91        300        157        245
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ENSG00000118363       1262       1197       1351        849       1204
ENSG00000118369        504        390        492        226        553
ENSG00000118402        109         80        125         81        129
ENSG00000118407        244        220        215         61        218
ENSG00000118412        379        301        450        274        491
ENSG00000118418        500        373        621        338        494
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ENSG00000118454        721        793        789        629        869
ENSG00000118473        589        503        604        294       1468
ENSG00000118482       1734       1389       2247       1222       2245
ENSG00000118491          0          1          1          0          0
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ENSG00000118495       1426        949       1548        769       1387
ENSG00000118496        795        734       1019        849       1101
ENSG00000118503        275        390        360        266        366
ENSG00000118507         62        105         67         93         88
ENSG00000118508        957        700        900        372        793
ENSG00000118513          1          0          2          0          1
ENSG00000118514          4          2          4          1          4
ENSG00000118515       1833       2906       2217       1946       2836
ENSG00000118518       1099       1015       1223        818       1256
ENSG00000118520          0          1          0          0          0
ENSG00000118523       2897       4173       7640       8485       9989
ENSG00000118526       5488       8196       4592       3090       5105
ENSG00000118557          3          7          7          8          3
ENSG00000118564        957        908       1064        728       1092
ENSG00000118579        977       1017       1187        885       1182
ENSG00000118596        445        410        480        305        565
ENSG00000118600        254        219        229        186        254
ENSG00000118620         87         97        120         90        136
ENSG00000118640         23         21         43         12         12
ENSG00000118655        113        137        151        114        164
ENSG00000118680       4395       5021       6734       5182       5251
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ENSG00000118690         33         56         68         49         87
ENSG00000118702          0          0          0          0          0
ENSG00000118705       4631       4383       6626       3655       6196
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ENSG00000118733          0          0          0          0          0
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ENSG00000118785          0          0          0          0          3
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ENSG00000118816       4841       3792       5444       4099       5807
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ENSG00000118855       3446       2283       3304       1906       1866
ENSG00000118873       1377       1110       1443        807       1553
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ENSG00000118898       5629       4626       6558       3810       3268
ENSG00000118900       1394       1411       1299        952       1546
ENSG00000118903          0          0          0          0          0
ENSG00000118922        807        616        978        491        981
ENSG00000118939         19         28         40          6         37
ENSG00000118946          0          0          3          0          1
ENSG00000118960       1067       1048       1027        688        984
ENSG00000118961        365        277        340        152        486
ENSG00000118965        450        455        487        317        562
ENSG00000118971       4441       2559       4358       2298       3580
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ENSG00000118985       5368       6003       5914       3592       8523
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ENSG00000119004        287        215        382        228        276
ENSG00000119013        454        388        470        293        477
ENSG00000119041        633        569        789        499        801
ENSG00000119042        290        279        203        138        392
ENSG00000119048       1377       1307       1255       1143       1300
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ENSG00000119138        737       2715        772       2155        752
ENSG00000119139       1707       4747       3256       7261       2291
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ENSG00000119227        207        247        152        109        126
ENSG00000119231        587        583        775        541        834
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ENSG00000119285       1075       1018       1218        715       1331
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ENSG00000119333        398        260        476        213        366
ENSG00000119335       3777       3447       4681       3011       5018
ENSG00000119383       2140       1626       2342       1261       2100
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ENSG00000119396       1900       1754       2021       1261       2087
ENSG00000119397        268        208        330        151        356
ENSG00000119401        781        705        781        464        861
ENSG00000119402       1953       1800       2515       1379       2173
ENSG00000119403        852        682        859        417        563
ENSG00000119408       3064       1666       2985        978       3893
ENSG00000119411          0          1          2          0          0
ENSG00000119414       1000        888       1113        770       1262
ENSG00000119421        381        400        477        284        469
ENSG00000119431        198        143        144         79         68
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ENSG00000119446        440        444        442        312        483
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ENSG00000119487       3083       3169       3452       2153       2766
ENSG00000119508         99        464         60        122        105
ENSG00000119509        380        321        371        180        447
ENSG00000119514        487        234        648        123        198
ENSG00000119522        355        329        425        246        488
ENSG00000119523        677        738        839        623        850
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ENSG00000119537       2329       2446       2156       2332       2115
ENSG00000119541       1261       1311       1343       1092       1437
ENSG00000119547          2          2          3          0          4
ENSG00000119559        496        471        486        290        441
ENSG00000119574        301        273        365        192        266
ENSG00000119596       2051       1707       2373       1427       2609
ENSG00000119599        152        149        205        117        204
ENSG00000119608         56         31         58         20         49
ENSG00000119614          0          0          0          0          0
ENSG00000119616        913        808       1026        650        919
ENSG00000119630        887        648        998        311       2128
ENSG00000119632        834        592        750        411        627
ENSG00000119636         32         43         63         35         64
ENSG00000119638       4358       3617       4185       2606       4610
ENSG00000119640        157        130        172         88        272
ENSG00000119650        315        282        336        208        322
ENSG00000119655       2680       1883       3876       2262       4076
ENSG00000119660          0          0          0          0          0
ENSG00000119661        212        214        219        128        207
ENSG00000119669       1394       1447       1687        788       1883
ENSG00000119673        362        549        351        298        365
ENSG00000119681      35519      24933      39674      16445      29619
ENSG00000119682       1061       1006       1251        785       1255
ENSG00000119684        337        230        533        266        391
ENSG00000119685        426        388        542        337        568
ENSG00000119686         27         26         56         38         43
ENSG00000119688        649        468        785        338        640
ENSG00000119689       4027       4642       5463       3385       5608
ENSG00000119698         74         89         67         31        207
ENSG00000119699        194        139        276        198        243
ENSG00000119703         40         17         51         16         55
ENSG00000119705        306        297        293        178        294
ENSG00000119707       2327       2040       3067       1623       3364
ENSG00000119711        330        561        391        664        408
ENSG00000119714        128          6         81          8         62
ENSG00000119715          0          2          1          3          3
ENSG00000119718        368        286        494        201        700
ENSG00000119720        254        190        323        169        325
ENSG00000119723         75         60         94         32         86
ENSG00000119725          8          7         12          3         10
ENSG00000119729       2914       3412       3930       2444       4290
ENSG00000119737          6         17         22          8         25
ENSG00000119760        839        687        946        471        998
ENSG00000119771        671        813       1098        685       1139
ENSG00000119772        329        175        343        121        391
ENSG00000119777       2024       1940       2211       1443       2370
ENSG00000119778        273        224        291        153        297
ENSG00000119782          9          9         33         13         16
ENSG00000119787        360        474        434        330        382
ENSG00000119801       2087       1955       2380       1848       2427
ENSG00000119812       1010        977       1165        673       1294
ENSG00000119820       1268       1186       1201       1075       1205
ENSG00000119844        468        426        559        362        631
ENSG00000119862         60         49         35         18         37
ENSG00000119865        605        564        701        458        659
ENSG00000119866          1          0          0          0          2
ENSG00000119878        343        264        294        205        368
ENSG00000119888          0          2          0          0          1
ENSG00000119899        941        947       1733       1573       1519
ENSG00000119900        678        694        610        550        705
ENSG00000119906        903        643       1030        534       1268
ENSG00000119912        966        773       1022        634       1231
ENSG00000119913          0          0          0          0          0
ENSG00000119915         25         42         32         16         54
ENSG00000119917       1085        741        908        685        864
ENSG00000119919          0          0          0          0          0
ENSG00000119922        543        211        559        287        432
ENSG00000119927        418        398        435        243        402
ENSG00000119929        172        209        191        105        199
ENSG00000119938       4727       2852       5677       2038       4129
ENSG00000119943        287        203        373        105        245
ENSG00000119946         76         91         56         25         49
ENSG00000119950       1679       1256       1581       1145       1611
ENSG00000119953        545        621        623        515        639
ENSG00000119965        211        160        236        125        195
ENSG00000119969         88         58        102         61         91
ENSG00000119973          0          0          0          0          0
ENSG00000119977       2797       1542       3041       1431       2303
ENSG00000119979       1237       1240       1518       1128       1798
ENSG00000119986        649        678        892        440        864
ENSG00000120008       1964       1789       2311       1533       2093
ENSG00000120029        605        589        708        432        701
ENSG00000120049         19         20         31         11         29
ENSG00000120051         13         10         15          7         18
ENSG00000120053        333        303        399        246        464
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ENSG00000120055          1          3          0          0          0
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ENSG00000120063       1309       1158       1182        827       1248
ENSG00000120068         11         10         11          7          0
ENSG00000120071       1133        897       1059        572       1329
ENSG00000120075         78         62        128         73         29
ENSG00000120088          0          0          0          0          0
ENSG00000120093        911        776       1071        591       1031
ENSG00000120094          0          0          0          0          0
ENSG00000120129        665       5020       1213       4541        816
ENSG00000120137       1146        908       1144        621       1172
ENSG00000120149        226        104         91         32        135
ENSG00000120156        164        126        374        134        291
ENSG00000120158        100         97        112         63        112
ENSG00000120159        256        189        295        173        291
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ENSG00000120162         15         72         14         62         14
ENSG00000120210          0          0          0          0          0
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ENSG00000120215          5          8         10          4         13
ENSG00000120217        174         70        160         50        120
ENSG00000120235          0          0          0          0          0
ENSG00000120242          1          0          0          0          0
ENSG00000120251          0          1          1          1          0
ENSG00000120253        505        447        520        324        527
ENSG00000120254       1420        919       2005        541       2150
ENSG00000120256        962        700       1365        793       1109
ENSG00000120262         56         45        147         83        124
ENSG00000120265        991       1095       1071        779       1083
ENSG00000120278        735        453        707        256        437
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ENSG00000120289          0          0          0          0          0
ENSG00000120306        503        478        590        377        442
ENSG00000120314        482        407        473        256        548
ENSG00000120318        329        224        377        138        415
ENSG00000120322         38         33         69         25         97
ENSG00000120324         86         74         95         47        188
ENSG00000120327         81         73        106         51        191
ENSG00000120328         21         15         24          7         30
ENSG00000120329          0          1          0          0          0
ENSG00000120332          1          0          0          0          0
ENSG00000120333        434        399        524        274        472
ENSG00000120334        118         87        106         63        111
ENSG00000120337          2          0          3          3          0
ENSG00000120341          9          5          9          2          1
ENSG00000120370        376        231        424        173        472
ENSG00000120436          0          0          0          0          0
ENSG00000120437        142        177        154         84        121
ENSG00000120438       2670       2480       2802       1819       2958
ENSG00000120440          0          0          0          0          0
ENSG00000120451       3733       3343       3727       1998       4185
ENSG00000120457          2          2          2          3          3
ENSG00000120458        186        165        212        119        282
ENSG00000120471          0          0          0          0          0
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ENSG00000120500          1          3         17         10         25
ENSG00000120509        589        462        731        368        749
ENSG00000120519        148        107        129         84        119
ENSG00000120526        206        272        225        186        222
ENSG00000120533        619        652        745        462        716
ENSG00000120539        161        150        254        178        264
ENSG00000120549         41         10         98         26        117
ENSG00000120555          7          8          4          1          8
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ENSG00000120586          0          5          0          0          0
ENSG00000120594        793       1031        870       1166        503
ENSG00000120616        373        335        490        242        462
ENSG00000120645          8          3          7          5         12
ENSG00000120647        120        103        186         96        171
ENSG00000120656        464        389        602        312        659
ENSG00000120658        278        305        254        167        366
ENSG00000120659          0          0          0          0          0
ENSG00000120662        162        138        147         95        184
ENSG00000120664          0          9         14          7          6
ENSG00000120669         10          5          6          9          2
ENSG00000120675        580        718        572        389        581
ENSG00000120685        494        428        613        351        611
ENSG00000120686       1826       1635       2079       1324       2372
ENSG00000120688        315        368        406        304        442
ENSG00000120690       1008       1570       1098       1256       1064
ENSG00000120693        301        212        548        269        688
ENSG00000120694       1164       1046       1357        740       1839
ENSG00000120696        207        128        257         88        219
ENSG00000120697        403        445        475        326        577
ENSG00000120699        257        199        233        136        281
ENSG00000120705       2588       2927       2885       2113       3410
ENSG00000120708       6298       3079      13768       6434      23194
ENSG00000120709       1183        949       1219        723       1247
ENSG00000120725        756        553        906        490        843
ENSG00000120727        515        543        634        373        681
ENSG00000120729          0          0          1          1          5
ENSG00000120733       1912       1670       2340       1292       2374
ENSG00000120738        894        209        780        201        883
ENSG00000120742       2002       1755       2212       1300       2036
ENSG00000120756          6          2         20          4         16
ENSG00000120784        224        195        223        186        211
ENSG00000120798        447        423        543        393        584
ENSG00000120800        699        748        688        612        840
ENSG00000120802        583        327        599        314        605
ENSG00000120805       2398       1625       2996       1580       2514
ENSG00000120820        857        540       1464        677       1382
ENSG00000120832        188        281        266        196        188
ENSG00000120833         91         76        102         46        147
ENSG00000120837        884       1762       2250       2408        990
ENSG00000120860        892        841       1080        595       1039
ENSG00000120868        581        495        498        297        571
ENSG00000120875          8          4          0          0          4
ENSG00000120885      15180      10082      22895      12981      16518
ENSG00000120889       3080       2050       3140       1260       3411
ENSG00000120896       2724       3189       3132       2627       2527
ENSG00000120899        201        229        427        623        278
ENSG00000120903          0          0          0          0          0
ENSG00000120907          0          1          0          0          0
ENSG00000120910        290        339        335        295        380
ENSG00000120913       1174       1038       1207        647        915
ENSG00000120915         64         45         60         23         30
ENSG00000120925        592        533        675        439        744
ENSG00000120937          0          0          0          0          0
ENSG00000120942        218        256        233        252        269
ENSG00000120948       2751       2080       3353       1614       3519
ENSG00000120949          1          1          4          1          0
ENSG00000120952          0         14          0          0          0
ENSG00000120963        826        583        919        505        752
ENSG00000120992        429        470        431        351        461
ENSG00000121005         17          9         12          9          0
ENSG00000121022        686        571        801        448        821
ENSG00000121039       6768       3522      13898       6257       7819
ENSG00000121053          1          2          4          2          2
ENSG00000121057        397        472        416        285        358
ENSG00000121058        310        246        269        189        329
ENSG00000121060       1547       1223       1565        907       1716
ENSG00000121064       2693       1934       3386       2111       3171
ENSG00000121067        920        779       1072        690       1015
ENSG00000121068       3247       3479       2969       1900       3041
ENSG00000121073        482        419        508        319        581
ENSG00000121075        581        640       1088        664        436
ENSG00000121089         25         15          7          7         30
ENSG00000121101          5          4          6          1          4
ENSG00000121104        187        103        210         95        186
ENSG00000121152         13         13         13         13          9
ENSG00000121207          9          4         11          6          3
ENSG00000121210        461        255        707        236        649
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ENSG00000121236        116         79        130         66        134
ENSG00000121270          5          4          3          4         17
ENSG00000121274        329        294        324        244        401
ENSG00000121281        133        119        183         65         96
ENSG00000121289        467        419        464        294        549
ENSG00000121297       1135        750       1034        480       1105
ENSG00000121310        864        770       1441        709       1229
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ENSG00000121316         45         28         42         26         38
ENSG00000121318          2          1          8          5          4
ENSG00000121335          1          0          2          2          3
ENSG00000121350        116        104        148        102        189
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ENSG00000121361        102        220        171        150        116
ENSG00000121377          0          0          0          0          0
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ENSG00000121390        644        615        661        373        640
ENSG00000121406        161         98        174         86        141
ENSG00000121410          8         10         12          3          7
ENSG00000121413        269        202        464        236        394
ENSG00000121417        182        138        296         98        320
ENSG00000121440       2980       3203       3012       1672       2537
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ENSG00000121454         81         47        105         26        127
ENSG00000121481        372        279        380        188        440
ENSG00000121486        514        414        711        397        581
ENSG00000121542        213        163        254        151        292
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ENSG00000121578        381        350        558        334        531
ENSG00000121579       2572       2197       2356       1615       3774
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ENSG00000121653        326        188        277         73        291
ENSG00000121671        560        364        732        397        701
ENSG00000121680        275        319        262        174        266
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ENSG00000121741       1497       1451       1635        984       1955
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ENSG00000121749        975        946       1115        752       1138
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ENSG00000121864        422        348        388        237        474
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ENSG00000121879        899       1080        916        908       1080
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ENSG00000121898       1675       1056       4707       2796       2166
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ENSG00000121904       1058       1022        752        378        867
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ENSG00000121931        160        169        247        168        142
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ENSG00000121940        403        452        605        343        692
ENSG00000121957        445        581        355        304        589
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ENSG00000122008        524        517        633        405        661
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ENSG00000122034        546        533        643        377        662
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ENSG00000122085        417        324        531        227        556
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ENSG00000122176      15976      11539      22654      10885      12903
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ENSG00000122203       2089       1713       2486       1829       2512
ENSG00000122218       7406       6262       8380       4439       8508
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ENSG00000122390         33         22         32         17         25
ENSG00000122406      14410      13690      14490       8626      15556
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ENSG00000122507        633        446        676        353        777
ENSG00000122512        341        224        407        196        384
ENSG00000122515       1058        954       1306        703       1108
ENSG00000122543          3          0          2          1          1
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ENSG00000122643        244        230        263        184        242
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ENSG00000122674        753        823       1322        767       1191
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ENSG00000123179        325        436        313        234        314
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ENSG00000123240       4783       3944       6780       3662       5432
ENSG00000123243      23586       9968      30467       8792       1244
ENSG00000123268        409        360        475        303        457
ENSG00000123297        169        157        202        140        178
ENSG00000123307          0          0          0          0          0
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ENSG00000123342        551        712        565        409        660
ENSG00000123349       3961       3680       5632       2851       5097
ENSG00000123352        776        450        771        338       1067
ENSG00000123353         67         69        119         73        117
ENSG00000123358        130        193        101        120        101
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ENSG00000123364          0          2          0          0          0
ENSG00000123374        248        184        230        146        221
ENSG00000123384      88031      66581     106554      45594      90403
ENSG00000123388          0          0          0          0          0
ENSG00000123395        274        260        269        177        259
ENSG00000123405         15          2         42          3         23
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ENSG00000123411        290        160        376        135        330
ENSG00000123415        268        219        361        158        295
ENSG00000123416       2490       1012       2164        571       1526
ENSG00000123427        148        126        115         75        162
ENSG00000123444        123         95        151         92        112
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ENSG00000123453         40         19         68         43         18
ENSG00000123454          3          1          2          2          2
ENSG00000123472        685        568        836        498        856
ENSG00000123473         87         62        137         73        120
ENSG00000123485         28         32         28         16         26
ENSG00000123496        143        113        383        225        181
ENSG00000123500          4          5          7          7         32
ENSG00000123505        512        599        572        371        474
ENSG00000123545        105        131        135        116        218
ENSG00000123552        251        247        204        143        275
ENSG00000123560         13          6          3          3          7
ENSG00000123561          0          0          0          0          0
ENSG00000123562       3537       5872       3642       4710       4197
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ENSG00000123572         50        184         88         67         30
ENSG00000123575        648        617        721        547        700
ENSG00000123576          0          0          0          0          0
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ENSG00000123595        545        513        546        408        693
ENSG00000123600        486        481        553        327        741
ENSG00000123607        360        388        409        291        472
ENSG00000123609        288        191        286        156        314
ENSG00000123610        444        136        303         36       1170
ENSG00000123612         35         12         33          6         27
ENSG00000123636        663        407        790        386        977
ENSG00000123643        617        723        618        595        687
ENSG00000123684        894        932       1182        795       1212
ENSG00000123685         16         29         22         76         30
ENSG00000123689         35         11        126          5         93
ENSG00000123700        810        567        738        490       1242
ENSG00000123728        549        483        603        370        624
ENSG00000123737        321        464        395        293        546
ENSG00000123739        557        461        714        417        723
ENSG00000123810         59         50         52         22         48
ENSG00000123815        479        361        522        196        423
ENSG00000123836        360        288        351        244        361
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ENSG00000123892         27         24         67         33         42
ENSG00000123901          0          1          2          0          0
ENSG00000123908        371        392        314        212        379
ENSG00000123933       4329       3592       3889       1692       4031
ENSG00000123965         54         53         68         39        106
ENSG00000123975        246        287        266        170        365
ENSG00000123977          0          7          3          5          1
ENSG00000123983       3219       2073       4600       1812       3107
ENSG00000123989       2219       2541       3761       1965       3160
ENSG00000123992       1963       1708       2036        965       2073
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ENSG00000124006       1399       1477       1464       1068       1490
ENSG00000124019          0          1          0          0          0
ENSG00000124067       1836       1692       1897        980       1778
ENSG00000124074        228        226        324        142        289
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ENSG00000124098       3381       2790       2802       1633       2877
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ENSG00000124103          4          3          4          0          2
ENSG00000124104       1341        740       1362        346        932
ENSG00000124107         27         25         14          6          6
ENSG00000124116         18         13         27          6          3
ENSG00000124120        809        791        960        685        891
ENSG00000124126        165         77        269        125        265
ENSG00000124134         46          7         24          1        110
ENSG00000124140          7          6          9          5          4
ENSG00000124143          0          0          0          0          0
ENSG00000124145       6146       3609       9582       3671       5690
ENSG00000124151        850       1382       1038       1632        988
ENSG00000124155       5094       4209       5898       3237       6354
ENSG00000124157          0          0          0          0          0
ENSG00000124159          2          2          6          1          3
ENSG00000124160        770        688        702        429        838
ENSG00000124164       1089       1076       1242        880       1350
ENSG00000124171          6          8         24         18         11
ENSG00000124172       2576       2608       2848       1621       2722
ENSG00000124177       1631       1016       1775        796       1990
ENSG00000124181       1540       1378       1577        836       1912
ENSG00000124191        257        200        162         69        378
ENSG00000124193       2800       2454       3545       1682       3771
ENSG00000124194          5          0          2          1          3
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ENSG00000124198       1378       1414       1554       1242       1681
ENSG00000124201       3182       2661       3734       2350       3670
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ENSG00000124207       1342       1123       1581        916       1540
ENSG00000124208          0          0          0          0          0
ENSG00000124209       1059        989       1432        888       1455
ENSG00000124212      11476       7057      20399       7265       6125
ENSG00000124214       2859       2415       3566       2055       3626
ENSG00000124215          5          7          7          4          1
ENSG00000124216         83         56         72         18        110
ENSG00000124217        191        178        201        108        168
ENSG00000124222       1259       1069       1315        812       1341
ENSG00000124224        171        144        199         90        205
ENSG00000124225        209         79        155         43        393
ENSG00000124226       1701       1232       2031        835       2043
ENSG00000124227          0          0          0          0          0
ENSG00000124228        698        713        784        452        856
ENSG00000124232          0          0          0          0          0
ENSG00000124233          0          0          0          0          0
ENSG00000124237          0          0          0          0          0
ENSG00000124243        224        158        398        173        275
ENSG00000124249         61         22        270         49        216
ENSG00000124251         11          8          4          3         11
ENSG00000124253          0          1          0          0          0
ENSG00000124256          0          0          0          0          0
ENSG00000124257         16          6         18          9          7
ENSG00000124260          0          0          0          0          0
ENSG00000124275        617        511        550        297        672
ENSG00000124279        106         89        121         58        126
ENSG00000124299       1703       1326       1810       1002       2025
ENSG00000124302          0          0          0          0          0
ENSG00000124313        314        277        383        249        349
ENSG00000124333        952        792       1158        709       1102
ENSG00000124334          0          0          0          0          1
ENSG00000124343       1207        911       1270        777       1446
ENSG00000124356        663        543        732        419        775
ENSG00000124357       1626       1144       1593        704       1452
ENSG00000124370        196        130        212        105        204
ENSG00000124374         17         27         16         30         20
ENSG00000124380        358        323        393        240        449
ENSG00000124383        504        437        612        339        711
ENSG00000124391          0          1          0          0          1
ENSG00000124399         16          7         18          6         15
ENSG00000124406         34         16         37         24         17
ENSG00000124422       4613       3210       4780       2221       5363
ENSG00000124429          0          0          0          0          0
ENSG00000124440         42        199         72        255         33
ENSG00000124444        143        112        144         74        153
ENSG00000124449          0          1          0          0          1
ENSG00000124459        317        181        341        137        348
ENSG00000124466         17         10         47          8         34
ENSG00000124467          8          3        141         51         25
ENSG00000124469          0          0          0          0          0
ENSG00000124479          4          0          5          0          0
ENSG00000124486       4145       4242       5825       4503       5065
ENSG00000124490          0          0          0          0          0
ENSG00000124491          0          0          0          0          0
ENSG00000124493          2          1          1          0          0
ENSG00000124496        646        324        791        212        693
ENSG00000124507          4          2         10          3          0
ENSG00000124508        211        134        350        156        292
ENSG00000124523        202        159        229        147        241
ENSG00000124529          0          0          0          0          0
ENSG00000124532        294        250        348        197        355
ENSG00000124535        787        696        796        479        768
ENSG00000124541        508        492        523        276        631
ENSG00000124549        128        114        210        100        189
ENSG00000124557          2          1          0          1          1
ENSG00000124562        749        673        812        402        824
ENSG00000124564          0          0          0          0          0
ENSG00000124568          0          0          0          0          0
ENSG00000124570       1816       1505       1910        926       2261
ENSG00000124571        521        515        572        381        733
ENSG00000124574        596        556        745        356        498
ENSG00000124575          1          0          1          0          0
ENSG00000124578          0          0          0          0          0
ENSG00000124587        932        815        512        374        617
ENSG00000124588        327        254        277        140        341
ENSG00000124593         95         99         92         68        100
ENSG00000124596        334        315        401        271        428
ENSG00000124602          2          4          5          3          3
ENSG00000124608        576        301        535        126        498
ENSG00000124610          0          0          0          0          0
ENSG00000124613        129         95        131         70        209
ENSG00000124614         11         10         17         10         19
ENSG00000124615        500        569        475        358        607
ENSG00000124635         46         42         39         31         41
ENSG00000124641        405        376        425        246        398
ENSG00000124657          0          0          0          1          1
ENSG00000124659        483        585        553        298        505
ENSG00000124664          0          1          0          0          1
ENSG00000124678          0          0          3          0          4
ENSG00000124688        260        297        315        214        302
ENSG00000124693          0          0          0          0          0
ENSG00000124701          1          1          0          1          3
ENSG00000124702        930       1086        920        876        939
ENSG00000124713          5          3          8          5          9
ENSG00000124721          0          0          1          0          0
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ENSG00000124733        658        548        861        362        899
ENSG00000124743          4          0          2          4          3
ENSG00000124749        145         84         90         99        108
ENSG00000124762      14568       6413      10122       2749      13293
ENSG00000124766       2483        406       2057        185       2829
ENSG00000124767       1443       1348       1924       1233       1842
ENSG00000124772         12          8         17          9          8
ENSG00000124780          0          0          0          0          0
ENSG00000124782        623        481        683        418        721
ENSG00000124783       2872       2239       3140       1942       3023
ENSG00000124784        301        291        353        218        369
ENSG00000124785          5          1         26         12          5
ENSG00000124786        690        575        684        557        732
ENSG00000124787         63         52         68         39         95
ENSG00000124788       1752       1221       1883        694       1421
ENSG00000124789       1161       1004       1169        710       1213
ENSG00000124795       2389       2258       2882       2152       2951
ENSG00000124802         54         48         47         37         51
ENSG00000124812          0          0          0          0          0
ENSG00000124813        102        121        131        100        206
ENSG00000124818          0          1          1          0          0
ENSG00000124827          0          0          0          0          1
ENSG00000124831       1611       1663       1758       1610       1704
ENSG00000124835          0          1          2          0          3
ENSG00000124839          1          4          3          3          7
ENSG00000124875         10          9          5          6         90
ENSG00000124882          0          0          2          2         35
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ENSG00000124942      97093      92681     117069      76202      98058
ENSG00000125037       1040       1147       1271        875       1546
ENSG00000125046          1          0          1          0          0
ENSG00000125084          0          0          0          0          0
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ENSG00000125107       3872       2989       4349       2375       4528
ENSG00000125122         30         33         45         20         28
ENSG00000125124       1254        776       1394        724       1199
ENSG00000125144          0         94         21          4          4
ENSG00000125148       1654       6003       1370       3868       1355
ENSG00000125149        306        248        345        201        391
ENSG00000125166        911        723        832        499       1040
ENSG00000125170        393        350        568        305        411
ENSG00000125207          0          0          0          0          0
ENSG00000125245          0          0          0          0          0
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ENSG00000125247        439        284        218        109        426
ENSG00000125249        964        762        686        392       1070
ENSG00000125255          0          1          0          0          0
ENSG00000125257       1234       1265        913        931       1793
ENSG00000125266        956       1184       1684        887        420
ENSG00000125285          0          1          0          0          0
ENSG00000125304       3098       2553       3159       2233       3046
ENSG00000125319         28         25         25         15         17
ENSG00000125337          2          1          1          1          0
ENSG00000125347        579        332        746        361        604
ENSG00000125351        261        287        302        212        419
ENSG00000125352        151        157        156         95        160
ENSG00000125354        203        167        245        116        308
ENSG00000125355          8          9         11          6          8
ENSG00000125356        617        647        735        492        759
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ENSG00000125375        119        157        211        145        181
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ENSG00000125384        283        370        311        161        313
ENSG00000125385          0          0          0          0          0
ENSG00000125386        682        585        773        443        881
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ENSG00000125398        836        452       1049        234        559
ENSG00000125409         16         11         12          2          4
ENSG00000125414          0          1          0          0          0
ENSG00000125430        229        337        299        299        331
ENSG00000125434         83         91         85         58         79
ENSG00000125445        451        370        480        262        450
ENSG00000125447        560        576        804        383        702
ENSG00000125449        152        147        188        102        215
ENSG00000125450        425        439        437        305        462
ENSG00000125454         49         48         64         46         37
ENSG00000125457        131        143        183        141        125
ENSG00000125458        296        285        345        187        296
ENSG00000125459        315        274        376        168        326
ENSG00000125462          0          1          0          0          0
ENSG00000125482        259        210        338        187        353
ENSG00000125484       1085        849       1091        600       1089
ENSG00000125485        157        178        192        128        225
ENSG00000125492          1          1          0          0          0
ENSG00000125498          0          0          0          0          0
ENSG00000125503       1881       2824       2677       2050       2312
ENSG00000125505       1193        936       1695        928       1908
ENSG00000125508          2          3          0          3          1
ENSG00000125510         68         58         80         41        105
ENSG00000125514          0          0          0          0          0
ENSG00000125520       1309        950       1329        526       1205
ENSG00000125522          0          0          0          0          0
ENSG00000125531          6          5         14          4          9
ENSG00000125533          0          0          0          0          0
ENSG00000125534       2261       2089       2825       1351       2257
ENSG00000125538          0          0          0          0          6
ENSG00000125551         27         29         51         25         41
ENSG00000125571          0          0          0          0          0
ENSG00000125611        190        165        208         79        193
ENSG00000125618          2          2         50         19        125
ENSG00000125629        493        396        380        339        367
ENSG00000125630        269        218        319        161        299
ENSG00000125631          1          1          1          0          3
ENSG00000125633       1686       1302       1771        909       1993
ENSG00000125637         93         77        133         51         78
ENSG00000125648       1498       1262       1965       1109       2106
ENSG00000125650         62         78         56         35         52
ENSG00000125651       1496       1220       1860        865       1747
ENSG00000125652        298        315        278        125        218
ENSG00000125656        455        461        528        305        543
ENSG00000125657         19          3         24          4         20
ENSG00000125675        526        252        491        205        665
ENSG00000125676       1372       1861       1606       1881       1778
ENSG00000125686       1360       1216       1590        825       1592
ENSG00000125691      12812      12110      14127       7345      13870
ENSG00000125695          0          0          0          0          0
ENSG00000125703        247        222        263        161        288
ENSG00000125726          0          0          0          1          0
ENSG00000125730       7730       7217      14013       8498       4625
ENSG00000125731         31         25         20         12         39
ENSG00000125733       1498       1702       1597        906       1674
ENSG00000125734       1120       1042       1269        696       1745
ENSG00000125735          7          8         15          5          4
ENSG00000125740         17         20         17         18         16
ENSG00000125741        493        462        621        323        579
ENSG00000125743       1828       1667       2159       1139       2013
ENSG00000125744        240        248        256        229        294
ENSG00000125746        483        502        569        375        521
ENSG00000125753        830       1099        952        668        834
ENSG00000125755       1307       1234       1327        747       1418
ENSG00000125772        299        185        476        173        548
ENSG00000125775         28         35         22         21         53
ENSG00000125779        540        556        617        400        697
ENSG00000125780          0          0          0          0          0
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ENSG00000125798          0          0          0          0          0
ENSG00000125804          5          1          5          3          3
ENSG00000125810          0          0          0          0          0
ENSG00000125812        315        310        307        196        378
ENSG00000125813          0          0          0          0          0
ENSG00000125814        198        217        246        179        239
ENSG00000125815          0          0          0          0          0
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ENSG00000125817       2062       1956       1976       1221       1978
ENSG00000125818       1749       1602       2192       1400       1908
ENSG00000125820          0          0          0          0          0
ENSG00000125821        465        486        634        363        555
ENSG00000125823          0          0          0          0          0
ENSG00000125826       1484       1327       1692        907       1642
ENSG00000125827       1727       1418       2188       1737       2015
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ENSG00000125834        498        357        569        286        702
ENSG00000125835        527        636        440        337        395
ENSG00000125841       1180        953       1579        758       1561
ENSG00000125843        260        177        278        133        256
ENSG00000125844      14631      13438      17207       8391      17222
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ENSG00000125846        244        220        296        156        336
ENSG00000125848        259         34        305         30        431
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ENSG00000125868       8617      14135      16917      18250      12601
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ENSG00000125870        580        567        631        420        751
ENSG00000125871        267        247        370        281        272
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ENSG00000125875       1957       1729       1899        927       2096
ENSG00000125877        493        477        398        291        336
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ENSG00000125912       1332       1264       1360        803       1210
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ENSG00000125944       1919       1796       2117       1018       2376
ENSG00000125945        795        467       1081        464        854
ENSG00000125952       1042       1091        960        660       1037
ENSG00000125954          0          0          0          0          0
ENSG00000125962        133         99        202         77        192
ENSG00000125965        404        140        546         79        293
ENSG00000125966         36         34         74         66         83
ENSG00000125967        202        150        187         66        211
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ENSG00000125970       2433       1557       2874       1049       2454
ENSG00000125971       1171       1325       1723       1045       1885
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ENSG00000125977       1907       1868       2461       1428       2550
ENSG00000125991       4190       3556       4486       2347       4386
ENSG00000125995        389        383        432        240        410
ENSG00000125997          0          0          1          0          1
ENSG00000125998          0          0          1          0          0
ENSG00000125999          0          0          0          0          0
ENSG00000126001        916        601        984        400        884
ENSG00000126003        366        346        348        224        439
ENSG00000126005        596        627        960        541        726
ENSG00000126010          9          3          8          2          5
ENSG00000126012       1678       1533       1868        936       1996
ENSG00000126016        846        205        493         46        880
ENSG00000126062        842        980       1087        729        994
ENSG00000126067       1227       1070       1493        802       1540
ENSG00000126070        461        459        508        338        554
ENSG00000126088       1127        906       1782        799       1465
ENSG00000126091        249        191        244        150        257
ENSG00000126106        105        120        108         83         69
ENSG00000126107       1256        978       1438        682       1544
ENSG00000126214        565        588        470        439        483
ENSG00000126215        175        178        182        154        164
ENSG00000126216        549        463        563        319        565
ENSG00000126217          4          0          1          0          4
ENSG00000126218        202        290        359        305        268
ENSG00000126226        831        765       1010        588       1018
ENSG00000126231          3          2          2          2          5
ENSG00000126233          0          0          1          0          1
ENSG00000126243        287        292        303        198        323
ENSG00000126246          0          2          0          0          1
ENSG00000126247       6225       6303       7777       4764       7821
ENSG00000126249         15         17         29         26         29
ENSG00000126251          0          0          0          0          0
ENSG00000126254        930       1038        997        561        946
ENSG00000126259          0          0          0          0          0
ENSG00000126261       1507       1512       1597       1333       1869
ENSG00000126262          0          0          0          0          0
ENSG00000126264          8         12         16         12         12
ENSG00000126266          0          0          0          0          0
ENSG00000126267       1399       1357       1965        992       1907
ENSG00000126337          0          0          1          0          1
ENSG00000126351       1648       1639       1541       1150       1703
ENSG00000126353         28         18         28         13         36
ENSG00000126368        502        254        383        241        544
ENSG00000126391        599        668        531        441        507
ENSG00000126432       2403       2416       3061       1517       2519
ENSG00000126453        120        116        119         73        135
ENSG00000126456        506        450        560        290        515
ENSG00000126457       1284       1186       1461        644       1548
ENSG00000126458       1478       2081       2191       1670       1730
ENSG00000126460          9          6          7          3          6
ENSG00000126461       1246       1273       1414        901       1375
ENSG00000126464        682        627        749        375        765
ENSG00000126467          8          2          9          4         10
ENSG00000126500          9          3          8          2          3
ENSG00000126522        264        371        271        159        170
ENSG00000126524       1420       1811       2265       1527       1975
ENSG00000126542          0          0          2          0          1
ENSG00000126545          1          0          0          0          0
ENSG00000126549          0          0          0          0          0
ENSG00000126550          0          0          0          0          0
ENSG00000126561        673        965        846        706        770
ENSG00000126562         26          3         13          3         34
ENSG00000126581        868        910       1146        667       1056
ENSG00000126583          1          1          3          1          0
ENSG00000126602        357        249        266        113        349
ENSG00000126603        672        565       1276        496        633
ENSG00000126653        559        616        838        503        970
ENSG00000126698       1548       1252       1729        871       1923
ENSG00000126705        757        455        809        262        830
ENSG00000126709        716        533        734        655        694
ENSG00000126733          0          0          1          0          1
ENSG00000126746        780        724        828        426        840
ENSG00000126749        351        292        266        185        238
ENSG00000126752          0          0          0          0          0
ENSG00000126756        501        494        472        317        475
ENSG00000126759          3          2          1          2          5
ENSG00000126767        607        641        603        427        692
ENSG00000126768        224        227        225        121        224
ENSG00000126773       1602       1166       1626        757       1653
ENSG00000126775        892        600       1124        749       1028
ENSG00000126777       5197       4785       7622       6776       8377
ENSG00000126778        353        282        712        286        645
ENSG00000126785        975        479       1443        332        701
ENSG00000126787         22         15         15         15         20
ENSG00000126790        434        477        481        318        398
ENSG00000126803         71        336        187        463        260
ENSG00000126804        740        700        814        596        809
ENSG00000126814        378        302        455        254        503
ENSG00000126821        523        487        649        503        614
ENSG00000126822        256        184        273        119        238
ENSG00000126838         28         34         17         25          4
ENSG00000126856          0          0          0          0          1
ENSG00000126858        519        465        569        349        619
ENSG00000126860         28         13         41          8         31
ENSG00000126861        455        177        599        107        700
ENSG00000126870        445        358        654        333        636
ENSG00000126878        101         12        353         28        104
ENSG00000126882         27         15         28          7         30
ENSG00000126883       1053        815       1178        663       1099
ENSG00000126890          0          0          0          0          0
ENSG00000126895          0          0          0          0          0
ENSG00000126903        860        866        870        539        697
ENSG00000126934       2429       2216       2882       1959       3169
ENSG00000126945       1593       1422       1826       1064       1900
ENSG00000126947       1493       1212       1249        684       1429
ENSG00000126950       1231        388       1251        289       1053
ENSG00000126952          0          0          0          0          0
ENSG00000126953         70         66         82         41        102
ENSG00000126970        205        141        234        108        290
ENSG00000127022      13895      11488      16683       9603      17675
ENSG00000127054       1114       1102       1248        656       1246
ENSG00000127074          0          0          0          0          2
ENSG00000127080         59         51         55         25         82
ENSG00000127081         66         51        105         49        101
ENSG00000127083         89        391        173        299         61
ENSG00000127084          0          0          2          0          0
ENSG00000127124         17         20         20         13         21
ENSG00000127125        494        471        602        372        566
ENSG00000127129          0          0          0          0          0
ENSG00000127152          0          0          1          0          0
ENSG00000127184       2470       2123       2514       1514       2236
ENSG00000127191        162        116        196         84        156
ENSG00000127220        245        238        276        143        257
ENSG00000127241       6397       4345       9603       5142       9126
ENSG00000127249          1          4          4          2          4
ENSG00000127252          0          2          2          1          0
ENSG00000127311         25         34         52         20         40
ENSG00000127314       2778       3545       3605       2935       3890
ENSG00000127318          0          0          0          0          0
ENSG00000127324          5         44          2         32          0
ENSG00000127325          1          0          1          0          1
ENSG00000127328         32         42         31         26         41
ENSG00000127329         24         12         22          9          6
ENSG00000127334        636        515        692        480        758
ENSG00000127337        141         94        122         61        148
ENSG00000127362          1          2          3          2          2
ENSG00000127364          5         10         10          1          7
ENSG00000127366          5          5         13          5         12
ENSG00000127377          3          3         15         11          3
ENSG00000127399          7          3         12          2          5
ENSG00000127412          0          0          0          0          1
ENSG00000127415        658        523        517        258        443
ENSG00000127418        544        443        739        424        818
ENSG00000127419        455        398        460        227        477
ENSG00000127423          7          2         12          6          9
ENSG00000127445        654        665        757        445        657
ENSG00000127452        549        408        501        315        432
ENSG00000127463       1385       1020       1943       1100       1391
ENSG00000127472          4          6         22         15          2
ENSG00000127481       8598       6382       9103       4206      10071
ENSG00000127483       4577       3803       4642       2652       4799
ENSG00000127507         19         19         42         37         17
ENSG00000127511       1364       1119       1464        744       1649
ENSG00000127515          0          0          0          0          0
ENSG00000127526        900        727       1103        646       1000
ENSG00000127527        605        421        739        331        714
ENSG00000127528         88         70        210         60         94
ENSG00000127529          0          0          0          0          0
ENSG00000127530          0          0          0          0          0
ENSG00000127533          0          2          1          0          0
ENSG00000127540        245        196        227        164        236
ENSG00000127554        177        198        162         87        146
ENSG00000127561         24         51         17         12         31
ENSG00000127564          9          9          4          2          2
ENSG00000127578          1          3          5          1          8
ENSG00000127580        181        151        217        101        184
ENSG00000127585          6         10          8         11         15
ENSG00000127586        123         71        114         41         79
ENSG00000127588          0          0          0          0          0
ENSG00000127589        603        218        522        100        448
ENSG00000127603       9826       8341      12595       7970      11532
ENSG00000127616       1600       1351       1848        870       2308
ENSG00000127663       1446       1449       1284        764       1431
ENSG00000127666        241        280        294        196        241
ENSG00000127720         88         53         85         57        120
ENSG00000127743          0          0          1          0          2
ENSG00000127774         13          4          8          7         14
ENSG00000127780          0          0          0          0          0
ENSG00000127804        711        455        733        422        803
ENSG00000127824        382        106        349         61        445
ENSG00000127831          0          1          1          0          0
ENSG00000127837       1343       1537       1420        882       1368
ENSG00000127838        489        481        455        237        381
ENSG00000127863       1920        733       2242        634       3318
ENSG00000127870        665        681        829        516        954
ENSG00000127884       1235        948       1257        632       1370
ENSG00000127903          3          2          9          7         12
ENSG00000127914       1241       1185       1826        967       1780
ENSG00000127920        627        820        809        456       1235
ENSG00000127922        710        677        847        511        767
ENSG00000127928          0          0          0          0          3
ENSG00000127946       1206       1194       1303       1039       1267
ENSG00000127947       1515       1718       1653       1335       1752
ENSG00000127948        936       1037        790        494        938
ENSG00000127951         72         25        316        130        123
ENSG00000127952        404        270        478        238        505
ENSG00000127954         13        247         25        889          2
ENSG00000127955        425        521        419        351        730
ENSG00000127957         82         80        110         42        100
ENSG00000127980        464        333        460        261        424
ENSG00000127989        150        128        193        144        169
ENSG00000127990       1589       1358       2579       1594       1711
ENSG00000127993        248        239        230        166        255
ENSG00000127995        328        282        356        200        362
ENSG00000128000        312        211        377        119        286
ENSG00000128011         10          8         13          4         14
ENSG00000128016       1724       1805       1507       1134       1627
ENSG00000128039        126        156        116        107        143
ENSG00000128040          0          0          0          0          0
ENSG00000128045          0         89         42        231         19
ENSG00000128050       1185        886       1209        531       1518
ENSG00000128052          1          3          1          1          4
ENSG00000128059        201        161        181         94        199
ENSG00000128159       1209       1262       1216        760       1072
ENSG00000128165        128         14        165         18         53
ENSG00000128185        732        630        686        377        764
ENSG00000128191        571        482        614        280        679
ENSG00000128203         21         25         26         21         60
ENSG00000128218          0          0          0          0          3
ENSG00000128228        128        149        121         43        110
ENSG00000128242          1          8          3          1          2
ENSG00000128245       1457       1407       1848        977       1306
ENSG00000128250          0          0          0          0          0
ENSG00000128253          0          0          0          0          1
ENSG00000128254          2          0          4          0          2
ENSG00000128262         39         65        117        124        116
ENSG00000128266         11         13          8          7          4
ENSG00000128268          0          3         14          4         25
ENSG00000128271          3          0          1          3          4
ENSG00000128272       5592       4216       7022       3537       7909
ENSG00000128274        834       1163       1381       1036       1334
ENSG00000128276          0          0          0          0          0
ENSG00000128283       1682       1688       1795       1030       1731
ENSG00000128284        354        498        567        540        332
ENSG00000128285         16          0         13          0         11
ENSG00000128294        195        207        285        164        436
ENSG00000128298         28         15         21         29         20
ENSG00000128309        434        806        376        426        481
ENSG00000128310          0          0          0          0          0
ENSG00000128311        189        382        195        314        210
ENSG00000128313          0          1          0          0          1
ENSG00000128322          0          0          0          0          0
ENSG00000128335        860        961       1315       1040       1086
ENSG00000128340         33         19         23         12         52
ENSG00000128342        254         36        223         16        317
ENSG00000128346        151        193        154         72        156
ENSG00000128383          3          2          0          0          3
ENSG00000128394        113         54        124         72        122
ENSG00000128408          6          0          6          2         14
ENSG00000128422          0          0          2          0          0
ENSG00000128438          0          0          0          0          0
ENSG00000128463       1075        901       1114        660       1104
ENSG00000128482         15         23         43         30         39
ENSG00000128487        157         76         93         35        302
ENSG00000128510         83         15        581         74        415
ENSG00000128512        871        816       1060        564       1465
ENSG00000128513        358        315        418        245        406
ENSG00000128519          0          0          0          0          0
ENSG00000128524        806        766        844        463        834
ENSG00000128534        315        266        340        219        356
ENSG00000128536         99         84         62         28        149
ENSG00000128563        432        379        565        239        524
ENSG00000128564          0         13          1          0          2
ENSG00000128567          4          1         15          6         16
ENSG00000128573        391        357        530        288        564
ENSG00000128578         55         45         66         25        149
ENSG00000128581        421        287        505        246        479
ENSG00000128585       1323       1124       1512        841       1717
ENSG00000128590        549        500        613        406        578
ENSG00000128591      12658      10698      15499       5748      14495
ENSG00000128594         36          8         28          8         16
ENSG00000128595      19804      19264      33875      19474      30628
ENSG00000128596        235        301        452        262        329
ENSG00000128602        553        226        439        114        108
ENSG00000128604          1          0          0          0          1
ENSG00000128606       2077        248       2446        390        923
ENSG00000128607        866        646        966        606       1046
ENSG00000128609        860        908       1089        661        875
ENSG00000128610          0          0          0          1          0
ENSG00000128617         51         66        110         78         75
ENSG00000128626        270        271        244        147        220
ENSG00000128641       2016       1316       2831        961       4361
ENSG00000128645          0          0          0          0          0
ENSG00000128652          2          1          0          0          0
ENSG00000128654        389        339        442        258        551
ENSG00000128655          0          1          1          1          1
ENSG00000128656       2214       1562       3655       1065       3506
ENSG00000128683          3          3          5          0          0
ENSG00000128692        453        406        486        274        499
ENSG00000128694        123         66        104         51        137
ENSG00000128699       1343       2349       1392       1825       1290
ENSG00000128708        455        362        582        297        617
ENSG00000128709          0          2          0          0          0
ENSG00000128710          0          0          0          0          0
ENSG00000128713          0          0          0          0          0
ENSG00000128714          0          0          0          0          0
ENSG00000128731       2897       2857       3132       1721       3156
ENSG00000128739         18          8         16          8         37
ENSG00000128789        791        768        770        534        785
ENSG00000128791      12170       9178       8712       5970      13259
ENSG00000128802          0          0          0          0          0
ENSG00000128805        494        292        425        118        545
ENSG00000128815         14         55         59         37         15
ENSG00000128829       2307       1962       2709       1493       4029
ENSG00000128833          1          0          2          2          1
ENSG00000128849         55         83        116         58         24
ENSG00000128872        794        745        864        569        879
ENSG00000128881        512        325        598        317        617
ENSG00000128886          5          2          2          1          1
ENSG00000128891         88         73        158         86        140
ENSG00000128908        944        975       1250        855       1064
ENSG00000128915        702        660        786        490        843
ENSG00000128917          2          5         33         65          6
ENSG00000128918          3          4          5          2          4
ENSG00000128923        886       1574       1255       1409        984
ENSG00000128928       1059        992       1309        899       1389
ENSG00000128944         70        102        148        141        118
ENSG00000128951        806        880        674        579        587
ENSG00000128965         67         20        188         52         99
ENSG00000128973        176        156        178        131        220
ENSG00000128989       1954       2150       2201       1655       2205
ENSG00000129003       2834       2021       2693       1589       2732
ENSG00000129007        107        119        155        104        102
ENSG00000129009       3908       2881       4875       2508       3194
ENSG00000129028         79         51         98         59         66
ENSG00000129038       4386       2874       5158       1827       4943
ENSG00000129048       1462        630       2238        292       2137
ENSG00000129055       1062        767       1083        593       1170
ENSG00000129071        520        494        654        353        773
ENSG00000129083       3546       3433       4086       2871       4589
ENSG00000129084        201        217        233        153        154
ENSG00000129103       3019       2810       3258       1993       2830
ENSG00000129116      12121      16666      21269      21811      18078
ENSG00000129128       2156       2571       3327       3328       2976
ENSG00000129151          2          2          5          3          3
ENSG00000129152          0          0          0          0          0
ENSG00000129158        123        107        123         84         92
ENSG00000129159          2          1          0          0          3
ENSG00000129167          6          3          5          1          2
ENSG00000129170          0          0          0          0          0
ENSG00000129173          4          6          1          0          4
ENSG00000129187       2106       1835       2154       1262       2353
ENSG00000129194         25         28         14          7         14
ENSG00000129195         11         22         14          4         11
ENSG00000129197        295        259        389        239        416
ENSG00000129204         47         48         71         53         68
ENSG00000129214         19         25         27         15         29
ENSG00000129219        793        677        857        470        763
ENSG00000129221          0          0          0          0          0
ENSG00000129226          0          0          1          0          1
ENSG00000129235        323        354        324        217        313
ENSG00000129244          2          1          2          3          4
ENSG00000129245        651        719        676        465        729
ENSG00000129250       4970       6014       8068       6144       7161
ENSG00000129255        621        597        716        364        798
ENSG00000129270          2         17          4          8          2
ENSG00000129277          0          0          0          0          0
ENSG00000129282         48         59         57         49         51
ENSG00000129292       1188       1168       1337        782       1752
ENSG00000129295         44         49         63         26         62
ENSG00000129315        665        641        731        495        692
ENSG00000129317        207        157        278        111        247
ENSG00000129347        421        412        493        284        546
ENSG00000129351       3330       2785       3220       1693       3516
ENSG00000129353       2792       3366       4671       3814       4436
ENSG00000129354          0          0          1          0          1
ENSG00000129355         82        110         74         64         58
ENSG00000129422        494        511        414        278        669
ENSG00000129437          2          1          2          2          2
ENSG00000129450          0          0          0          0          0
ENSG00000129451          0          0          0          0          0
ENSG00000129455          0          0          0          0          0
ENSG00000129460        259        243        277        159        281
ENSG00000129465         10         21         26         14         17
ENSG00000129467        163         57        233         24        192
ENSG00000129472        326        290        453        312        421
ENSG00000129473       1486       1569       1571       1294       1408
ENSG00000129474        492        334        704        293        759
ENSG00000129480        148        131        223        147        194
ENSG00000129484        248        116        336        104        296
ENSG00000129493        669        709        920        592        777
ENSG00000129514          5          9         12          1         11
ENSG00000129515       2530       2239       2882       1909       3097
ENSG00000129518        603        583        848        492        849
ENSG00000129521        206         40         96         22         23
ENSG00000129534        411        408        422        312        420
ENSG00000129535          9          7         15          8          9
ENSG00000129538          0          0          0          0          0
ENSG00000129559        445        429        399        280        412
ENSG00000129562       1628       1482       1926       1232       1553
ENSG00000129566        829        854       1005        681        901
ENSG00000129595          2          1          6          3          3
ENSG00000129596         56         47         84        187         20
ENSG00000129625       2686       2628       3659       2422       4051
ENSG00000129636       1587       1480       2015       1402       1843
ENSG00000129646         63         56         41         15         98
ENSG00000129654          0          0          0          0          0
ENSG00000129657       1398       1281       2011       1241       1907
ENSG00000129667         62         42         67         15        109
ENSG00000129673          0          0          2          0          2
ENSG00000129675        706        615       1087        563        905
ENSG00000129680        705        745        891        598        868
ENSG00000129682        379         72        476        119        108
ENSG00000129691        715        610        922        474        792
ENSG00000129696        128        144        138         70        158
ENSG00000129744          0          0          0          0          0
ENSG00000129749          7         11          6          4         13
ENSG00000129757        488        530        551        376        454
ENSG00000129810          4          3          8          3          3
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ENSG00000129824       4846       4155       4715       2513       5124
ENSG00000129845          0          0          0          0          0
ENSG00000129862          0          1          0          0          0
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ENSG00000129873          0          0          0          0          0
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ENSG00000129911        161        151        147         54        154
ENSG00000129925       2030       2054       1764       1158       2125
ENSG00000129932        163        184        176        103        139
ENSG00000129933       1231       1074       1286        759       1266
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ENSG00000129968       1183       1158       1202        630        939
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ENSG00000130005        506        308        477        204        458
ENSG00000130021        280        274        282        178        309
ENSG00000130023        423        379        567        318        525
ENSG00000130024        975        968       1200        731       1622
ENSG00000130032        180         30         49          7          0
ENSG00000130035          0          1          3          1          1
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ENSG00000130045         13         10         34          8         16
ENSG00000130052        132         81        138         74        277
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ENSG00000130066       2118       6302       2896       3480       3296
ENSG00000130119        198        174        199        102        215
ENSG00000130147       3176       2214       3962       1824       4267
ENSG00000130150        589        598        932        824        725
ENSG00000130158        678        450        739        404        789
ENSG00000130159        456        370        363        148        383
ENSG00000130164       1077       1003       1369        926        635
ENSG00000130165        586        479        669        341        585
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ENSG00000130175       4914       4837       6196       3462       5768
ENSG00000130176        460       1171       1538        969        666
ENSG00000130177       1431       1326       1652       1000       1812
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ENSG00000130193        115         49        116         53        120
ENSG00000130201          1          0          0          1          5
ENSG00000130202        933       1099       1269        783       1201
ENSG00000130203       2510       1479       2210       1243       5102
ENSG00000130204        365        396        400        197        440
ENSG00000130208         30         23         47         10        123
ENSG00000130222         28         10         11          4         10
ENSG00000130224        265        383        285        323        422
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ENSG00000130227       1866       1233       2221        939       2638
ENSG00000130234          0          0          0          0          0
ENSG00000130244        210        146        198         84        194
ENSG00000130254       1391       1482       1536        994       1490
ENSG00000130255       5685       5781       5765       2518       4976
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ENSG00000130283          0          0          0          0          0
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ENSG00000130299        139        123        151         76        117
ENSG00000130300          0          0          0          0          1
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ENSG00000130304        599        446        572        286        562
ENSG00000130305        326        303        287        172        275
ENSG00000130307          2          0          5          5          5
ENSG00000130309       1858       2009       1785       1228       1774
ENSG00000130311        562        723        609        478        637
ENSG00000130312        431        452        460        287        386
ENSG00000130313        841        712        931        397        989
ENSG00000130332        398        313        398        175        348
ENSG00000130338        580        378        622        270        749
ENSG00000130340       5275       3040       4434       2235       6764
ENSG00000130347         83         53         98         38         62
ENSG00000130348        286        232        267        136        447
ENSG00000130349        197        157        209        110        231
ENSG00000130363        317        217        416        254        416
ENSG00000130368          0          0          0          0          0
ENSG00000130377          4          0          9          0         11
ENSG00000130382        779        816        829        451        887
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ENSG00000130385          0          0          0          0          0
ENSG00000130396        654        613        663        387        768
ENSG00000130402       9585      12291      13120      10441      11413
ENSG00000130413         14         20         28         21         63
ENSG00000130414       1402       1267       1611        947       1744
ENSG00000130427          2          0          2          0          1
ENSG00000130429        907        866       1069        637        725
ENSG00000130433          0          0          2          2          2
ENSG00000130449        604        455        781        400       1008
ENSG00000130475          7          9         30         13         13
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ENSG00000130479        467        490        486        391        498
ENSG00000130487         20          2         23          1          2
ENSG00000130489         50         67         64         34         74
ENSG00000130508       8666       9708      13772       7683      15222
ENSG00000130511        812        590        692        285        719
ENSG00000130513        927        206        506         77        898
ENSG00000130517       1500        840       1507        767       1518
ENSG00000130518        139         60        215         71         66
ENSG00000130520        597        565        700        398        701
ENSG00000130522       1535       1133       1916        952       1443
ENSG00000130528          0          1          2          1          1
ENSG00000130529        452        676        552        462        413
ENSG00000130538          0          0          0          0          0
ENSG00000130540         44         56         46         22         31
ENSG00000130544        120         89        142         77        116
ENSG00000130545          2          0          1          0          0
ENSG00000130558        304        341        260        186        133
ENSG00000130559        622        411        605        359        697
ENSG00000130560        532        485        537        283        586
ENSG00000130561          0          2          0          0          0
ENSG00000130584        212         98        287         97        215
ENSG00000130589       1035        722        730        349        761
ENSG00000130590         51         36         53         27         53
ENSG00000130592         35          9         42          3          8
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ENSG00000130598          0          0          0          0          0
ENSG00000130600         58         14        148         30         52
ENSG00000130612          1          1          3          1          2
ENSG00000130635      13180       8003      13765       4648      10393
ENSG00000130638       1985       1840       2528       1538       2303
ENSG00000130640       1328       1171       1425        757       1510
ENSG00000130643          1          0          2          0          2
ENSG00000130649         16         14         45         14         30
ENSG00000130653        114        165        155        108        114
ENSG00000130656          0          0          0          0          0
ENSG00000130669        412        392        535        217        478
ENSG00000130675          0          0          0          0          0
ENSG00000130684         70         54         75         32         86
ENSG00000130695         78         55        103         61        119
ENSG00000130699        181        198        209        120        216
ENSG00000130700          0          0          0          0          0
ENSG00000130701          0          2          0          0          0
ENSG00000130702       1025        683       1534        750       1535
ENSG00000130703        633        556        718        409        774
ENSG00000130706        673        586        741        477        794
ENSG00000130707        953        632       1257        439       2406
ENSG00000130711          0          0          0          1          0
ENSG00000130713        193        134        249         96        234
ENSG00000130714        616        549        667        425        636
ENSG00000130717        634        583        632        379        701
ENSG00000130720         91         38         86         41        914
ENSG00000130723       4894       4141       5655       3081       5753
ENSG00000130724       1128       1082       1579        893       1678
ENSG00000130725        675        685        690        413        762
ENSG00000130726       3288       2844       3275       1887       3330
ENSG00000130731        488        458        540        234        434
ENSG00000130733        627        441        759        312        752
ENSG00000130734         74         92        101         52        105
ENSG00000130741       2487       1939       2734       1444       2873
ENSG00000130748         45         44         28         26         24
ENSG00000130749        695        599        816        413        721
ENSG00000130751         12          4         17          5          7
ENSG00000130755          5          1          3          1          2
ENSG00000130758        199        211        189        107        199
ENSG00000130762          1          0          2          0          2
ENSG00000130764        659        579        725        416        689
ENSG00000130766       1287        717       1240        306       1160
ENSG00000130768          0          0          1          0          1
ENSG00000130770        730        684        869        426        849
ENSG00000130772        253        243        249        179        234
ENSG00000130775        103         68         93         43        156
ENSG00000130779       4705       5121       6473       4155       5196
ENSG00000130783          5          4         11          5          4
ENSG00000130787        324        209        290        156        465
ENSG00000130803        557        452        697        369        676
ENSG00000130810         25         29         28         17         20
ENSG00000130811       1770       1964       2010       1239       2180
ENSG00000130812          2          4          9          3          6
ENSG00000130813        363        299        390        221        423
ENSG00000130816       2016       1738       1930       1051       2216
ENSG00000130818        242        171        270        124        286
ENSG00000130821        954        925        970        601       1169
ENSG00000130822          9         10          8          1         19
ENSG00000130826        475        455        510        262        630
ENSG00000130827       1648       1285       1652        695       1923
ENSG00000130829          0          0          1          0          1
ENSG00000130830        290        317        303        190        412
ENSG00000130844        228        206        300        170        361
ENSG00000130856        355        244        393        171        420
ENSG00000130876         15         10          6          7          6
ENSG00000130881        842        592        781        277        711
ENSG00000130921        356        233        385        171        450
ENSG00000130935        514        394        540        316        580
ENSG00000130939       2383       1695       2681       1590       2766
ENSG00000130940          0          1          6          3         13
ENSG00000130943         30         27         49         15         29
ENSG00000130948          0          1          2          4          3
ENSG00000130950          4          4          9          2          7
ENSG00000130956        716        942       1090       1032        822
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ENSG00000130958        499        511        505        413        490
ENSG00000130962        679        639        705        622       1052
ENSG00000130985       6833       5984       6876       3883       6897
ENSG00000130988        122         82        187        111        132
ENSG00000130997         63         60         44         22         54
ENSG00000131002        676        632        833        417       1089
ENSG00000131007          0          0          0          0          0
ENSG00000131013        621        545        833        461        965
ENSG00000131015         12         15         28         11         26
ENSG00000131016      37274      18475     104747      24110      38136
ENSG00000131018       3326       3010       3910       1872       3122
ENSG00000131019         45         15         68         21         38
ENSG00000131023        723        593        842        456        823
ENSG00000131037          4         14          4         11         15
ENSG00000131042          0          0          0          0          0
ENSG00000131043        702        672        745        500        732
ENSG00000131044          3          3          5          0          6
ENSG00000131050          4          2          0          0          0
ENSG00000131051       4668       4143       5256       2948       5952
ENSG00000131055          0          0          0          0          0
ENSG00000131059          0          0          0          0          0
ENSG00000131061         85         82        100         44         84
ENSG00000131067        678        624        766        406        712
ENSG00000131068          0          0          0          0          0
ENSG00000131069        618        618        722        522        782
ENSG00000131080       1463        725       1718        425       2100
ENSG00000131089        615        477        804        357        737
ENSG00000131094         23         14         26         12         76
ENSG00000131095          1          1          0          0          1
ENSG00000131096          2          2          6          0          5
ENSG00000131097          0          0          1          1          2
ENSG00000131100       1810       2075       2608       1746       2469
ENSG00000131115        173        138        212        104        233
ENSG00000131116        230        213        260        136        206
ENSG00000131126          0          0          1          1          1
ENSG00000131127        105         95        180         74        168
ENSG00000131142          1          0          0          0          1
ENSG00000131143       3486       3408       4472       2224       4610
ENSG00000131148        309        369        348        270        363
ENSG00000131149        818        574        983        392       1183
ENSG00000131152          0          0          0          0          0
ENSG00000131153         33         18         21          9         23
ENSG00000131165       1706       1677       1527        974       1294
ENSG00000131171       2688       2165       3429       2233       3593
ENSG00000131174        836        714       1213        516       1256
ENSG00000131183          0          0          0          0          0
ENSG00000131187          3          5          5          3         12
ENSG00000131188         24         25         33         12         45
ENSG00000131196        128        130        155         72        130
ENSG00000131203          1          0          0          0          0
ENSG00000131233          1          1          1          0          2
ENSG00000131236       6105       7067       7510       5921       6814
ENSG00000131238        716        682        911        565        792
ENSG00000131242         56         10         69         12         54
ENSG00000131263       1126       1086       1279        844       1291
ENSG00000131264          0          0          0          0          0
ENSG00000131269        297        233        359        179        381
ENSG00000131323        683        460        742        300        858
ENSG00000131351         47         39         25         20         37
ENSG00000131355          0          0          0          0          0
ENSG00000131368        592        467        639        409        611
ENSG00000131370        388        233        429        107        390
ENSG00000131373        186        194        221        149        237
ENSG00000131374       3903       2659       3593       1998       4224
ENSG00000131375        772        598        828        470        901
ENSG00000131378       1423       1234       1305       1103       2618
ENSG00000131379          3          2         10          0          4
ENSG00000131381        896        619       1118        682       1172
ENSG00000131386       5613      12745       7785      13192       9922
ENSG00000131389       1153        217       1874        233       1215
ENSG00000131398          2          4          0          1          3
ENSG00000131400         13         13          9          4          8
ENSG00000131401          0          1          0          1          0
ENSG00000131408       1608       1769       1709       1100       1470
ENSG00000131409         23          7         19          9         14
ENSG00000131435        407        299        471        184        268
ENSG00000131437        394        233        600        215        532
ENSG00000131446       3666       6111       4936       4589       3848
ENSG00000131459        671       1811        668        964        648
ENSG00000131462        558        461        589        205        627
ENSG00000131467       1602       1758       1621       1191       1929
ENSG00000131469       9800       9614       9304       4714       8878
ENSG00000131470         47         65         44         41         62
ENSG00000131471        216        226        285        172         80
ENSG00000131473       4006       4125       3821       2209       3850
ENSG00000131475        521        476        575        368        612
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ENSG00000131480         16         26         27         19         30
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ENSG00000131495        194        198        220        131        221
ENSG00000131503         24         20         22         13         24
ENSG00000131504       1417       1441       1828       1456       1816
ENSG00000131507       2416       2679       3008       2584       2764
ENSG00000131508       1114       1090       1111        986       1193
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ENSG00000131558       2362       1986       2706       1563       3011
ENSG00000131584       1702       1251       1366        476       1213
ENSG00000131591        111        114        137         64        151
ENSG00000131620        450        155       1742        818        575
ENSG00000131626       1053       1115       1223        750       1565
ENSG00000131634        371        461        324        305        207
ENSG00000131650          0          2          3          0          2
ENSG00000131652        247        180        196        108        198
ENSG00000131653       2406       2315       2344       1323       2905
ENSG00000131668          1          3          0          0          0
ENSG00000131669        487        239        596        231        853
ENSG00000131686          0          0          0          0          0
ENSG00000131697        280        187        207        108        223
ENSG00000131711       6944       3872       7449       3332       8010
ENSG00000131721          0          0          0          0          0
ENSG00000131724       1225       1021       2239       1375       2496
ENSG00000131725        521        543        580        364        655
ENSG00000131730         25         11         34          7         35
ENSG00000131732        713        518        731        289        908
ENSG00000131737          0          0          1          0          1
ENSG00000131738          0          0          1          0          1
ENSG00000131746          1          3          2          0          3
ENSG00000131747        339        310        270        134        359
ENSG00000131748        800        709        831        516        975
ENSG00000131759        809        712        824        356        852
ENSG00000131771        152         21        111         13         49
ENSG00000131773        191        190        156        128        127
ENSG00000131778        769        457        937        439        887
ENSG00000131779        510        488        614        439        583
ENSG00000131781         68         76         95         70         71
ENSG00000131788        820        635        883        453        761
ENSG00000131791        938        784       1214        683       1219
ENSG00000131795        605        540        633        374        698
ENSG00000131797         79         54         85         23         75
ENSG00000131808          0          0          0          0          0
ENSG00000131828        612        612        715        414        852
ENSG00000131831        495       1296        830       1280         74
ENSG00000131844        476        607        530        483        578
ENSG00000131845        275        233        350        180        336
ENSG00000131848         39         47         53         34         72
ENSG00000131849        163        102        228        116        226
ENSG00000131864          0          2          0          0          0
ENSG00000131871        631        924        751        679        715
ENSG00000131873        870        614        855        437        928
ENSG00000131876        350        292        335        168        233
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ENSG00000131899       1559       1055       1534        554       1554
ENSG00000131910          0          0          1          0          1
ENSG00000131914          0          0          0          1          2
ENSG00000131931        159        161        198        117        221
ENSG00000131941         95        129        120         82         74
ENSG00000131943        589        618        520        458        559
ENSG00000131944         83         64        102         55         77
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ENSG00000131966       1378       1174       1346        929       1471
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ENSG00000131979         41         83         54         82         38
ENSG00000131981       6689       4902       5756       2786       5436
ENSG00000131982          0          0          0          0          0
ENSG00000132000        136        133        462        183        532
ENSG00000132002       1789       1324       2032        960       1891
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ENSG00000132004         76         53         87         33         80
ENSG00000132005        163        164        204         90        178
ENSG00000132010          4          4          5          1          5
ENSG00000132016         15         14         15          6         14
ENSG00000132017        216        176        273        114        235
ENSG00000132024        516        414        616        324        714
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ENSG00000132031         30         38         74         58         48
ENSG00000132109        522        396        597        263        489
ENSG00000132122        227        247        262        200        330
ENSG00000132128       1813       1653       2068       1129       2371
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ENSG00000132142       1538        977       1766        784       1400
ENSG00000132153       1156       1094       1189        712       1367
ENSG00000132155       2243       3414       2482       2396       2160
ENSG00000132164          0          0          0          0          0
ENSG00000132170        321        774        282        270        614
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ENSG00000132199        433        299        561        143        398
ENSG00000132204          0          0          0          0          0
ENSG00000132205        590        433        577        243        707
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ENSG00000132254        718        581        795        390        972
ENSG00000132256        644        315        737        308        958
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ENSG00000132274       3161       2726       3465       1800       3978
ENSG00000132275        265        236        261        144        276
ENSG00000132286        365        336        453        303        420
ENSG00000132294       2840       2265       3206       1763       3648
ENSG00000132297          0          0          0          0          0
ENSG00000132300        960        818       1188        665       1090
ENSG00000132305       1113       1072       1339        786       1469
ENSG00000132313        498        414        581        320        585
ENSG00000132321         21          5         62         14         36
ENSG00000132323        380        395        413        223        407
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ENSG00000132330         21         32         27         12         34
ENSG00000132334         35         26         50         58         44
ENSG00000132341       2723       2820       3352       2007       3398
ENSG00000132356       1759       2873       1947       1975       1810
ENSG00000132357        641        703        648        551        752
ENSG00000132359         25         38         13          6         89
ENSG00000132361        736        972        826        551        928
ENSG00000132376        637        701        734        668        693
ENSG00000132382        727        746        869        484        906
ENSG00000132383       1461        950       1428        777       1571
ENSG00000132386      11094       7821      10100       5288      12216
ENSG00000132388        880        822        997        665       1118
ENSG00000132394        186        144        181         82        182
ENSG00000132405        629        453        607        264        713
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ENSG00000132424       3335       2781       3909       2055       4748
ENSG00000132429         72        111        113         69        250
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ENSG00000132436        221        148        223         92        192
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ENSG00000132467        502        617        668        403        644
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ENSG00000132471       1536       1370       1889       1242       1751
ENSG00000132475       3857       3054       4335       2052       4150
ENSG00000132478        435        291        384        154        424
ENSG00000132481         63         62         76         39         85
ENSG00000132485       1758       1722       1869       1251       2015
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ENSG00000132507       2635       2961       2423       1528       2487
ENSG00000132510        853        489        713        289       1066
ENSG00000132514          0          0          0          0          0
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ENSG00000132530        779        364        847        254        909
ENSG00000132535        527        390        590        271        569
ENSG00000132541        758        414        559        227        496
ENSG00000132549       2998       2102       3892       1781       4179
ENSG00000132554         51         49         78         43         72
ENSG00000132561       2969       2306       3557       1704       2447
ENSG00000132563        310        264        409        310        346
ENSG00000132570         61         54         89         57         85
ENSG00000132581        733        798        803        519        822
ENSG00000132589       1639       1749       2006       1591       2087
ENSG00000132591        451        480        506        340        545
ENSG00000132600        565        630        626        414        545
ENSG00000132603        226        266        268        199        339
ENSG00000132604        451        366        553        295        520
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ENSG00000132622        180         25         98         17         84
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ENSG00000132635        697        637        744        354        727
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ENSG00000132669        986        975       1152        834       1180
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ENSG00000132773         84         62        110         48        105
ENSG00000132780       1107        870       1106        609       1225
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ENSG00000132792        520        552        618        327        568
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ENSG00000132823        871       1001        744        694        995
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ENSG00000132840        428        320        466        212       1069
ENSG00000132842       1744       1559       2134       1396       2224
ENSG00000132846        314        247        366        124        265
ENSG00000132849        171        174        283        176        263
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ENSG00000132879        497        389        440        242        465
ENSG00000132881         50         60         76         55         53
ENSG00000132906        183        191        190        104        169
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ENSG00000132912       1536       1267       1782       1067       1740
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ENSG00000132950        301        242        319        160        334
ENSG00000132952        273        260        330        177        341
ENSG00000132953        621        560        741        466        823
ENSG00000132958          0          0          1          1          0
ENSG00000132963       1041       1102       1070        897        910
ENSG00000132964        298        231        251        227        402
ENSG00000132965          4         33         12          6          6
ENSG00000132967       1222       1094       1478        720       1809
ENSG00000132970        768       1524        965       1288       1165
ENSG00000132972          1          0          0          0          0
ENSG00000132975          0          0          0          0          0
ENSG00000133019          1          0          2          0          0
ENSG00000133020          0          0          0          0          0
ENSG00000133026       8418       9297      18605      16200       9340
ENSG00000133027        178        252        226        212        178
ENSG00000133028        329        276        458        269        466
ENSG00000133030       4825       4020       5416       2743       5730
ENSG00000133048         64         22        646        377        210
ENSG00000133055          1          1          4          4          3
ENSG00000133056        232        240        368        138        124
ENSG00000133059       1760       1234       2262        820       2089
ENSG00000133063          1          0          0          4          1
ENSG00000133065       1003       1029       1258        814       1659
ENSG00000133067          0          0          0          0          1
ENSG00000133069        228         87        239         60        176
ENSG00000133083        878        711        734        294        160
ENSG00000133101          0          3          4          3          1
ENSG00000133103        797        436        704        286        857
ENSG00000133104       2255       2862       1981       1804       2384
ENSG00000133105          0          0          1          0          0
ENSG00000133106        147        207        186        186        227
ENSG00000133107         12          9          8          4         64
ENSG00000133110       1710        469      12652       3357       4966
ENSG00000133111         87         67         87         34         57
ENSG00000133112      29731      27952      35621      23116      28744
ENSG00000133114        420        307        497        281        555
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ENSG00000133116          5          5         18         12          5
ENSG00000133119         69         57         98         52         81
ENSG00000133121        714       1135       1190        726        948
ENSG00000133124          0          1          0          0          0
ENSG00000133131        899        593       1022        577       1086
ENSG00000133134          5          3          2          0          2
ENSG00000133135         23         22         31         22         32
ENSG00000133136          7          8          6          5         15
ENSG00000133138        578        364        580        303        631
ENSG00000133142       1352       3490       1942       3851       2026
ENSG00000133149          0          0          1          0          0
ENSG00000133169          1          8          0          1          6
ENSG00000133193        342        237        362        195        396
ENSG00000133195        274        194        462        261        321
ENSG00000133216        471        159        342         47        935
ENSG00000133226       1570       1300       1799       1022       1916
ENSG00000133243       1888       1804       1914       1097       1892
ENSG00000133246          0          2          6          4          5
ENSG00000133247         86         60         95         39         83
ENSG00000133250        149        139        170         57        113
ENSG00000133256         13         19         29         18         39
ENSG00000133265        405        406        454        237        387
ENSG00000133275       1089        994       1182        614       1181
ENSG00000133302        139        126        135         94        110
ENSG00000133313        957        956        985        606       1111
ENSG00000133315        137        125        135         84        212
ENSG00000133316        193        239        205        148        252
ENSG00000133317          1          1          2          1          0
ENSG00000133318       3367       2974       3939       3050       3409
ENSG00000133321        528        354        688        371        463
ENSG00000133328          0          1          0          2          0
ENSG00000133392         21         22        102         95        263
ENSG00000133393        671        594        721        482        865
ENSG00000133398        452        429        500        358        463
ENSG00000133401         45         78         59         79         77
ENSG00000133422        691        705        826        509        952
ENSG00000133424        859        553       1335        507        846
ENSG00000133433        138        108         60         45        243
ENSG00000133454          0          1          1          1          0
ENSG00000133460        129         86        203        105        209
ENSG00000133466        340        223        355        142        347
ENSG00000133475          4          1          7          1          3
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ENSG00000133488          1          0          2          3          2
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ENSG00000133561          0          0          0          0          0
ENSG00000133574          0          0          0          0          0
ENSG00000133597        189        212        255        199        192
ENSG00000133606       1890       1818       2265       1596       2149
ENSG00000133612       1314       1235       1126        719       1150
ENSG00000133619        274        194        231        110        258
ENSG00000133624        281        249        322        176        351
ENSG00000133627         75         63        109         55         79
ENSG00000133636          0          0          0          0          0
ENSG00000133639       1230       1472       1108       1060       1416
ENSG00000133640          4          0          6          1         14
ENSG00000133641        229        278        237        196        262
ENSG00000133657       4076       3609       4460       3119       4352
ENSG00000133661          4          7         11         12         14
ENSG00000133665          3          1          0          0          2
ENSG00000133678        242        208        370        213        300
ENSG00000133687       2666       3640       6328       4999       7526
ENSG00000133703        637        566        961        487        737
ENSG00000133704       1397       1055       1657        900       1771
ENSG00000133706       1784       1534       1921       1191       2138
ENSG00000133710          1          0          0          0          0
ENSG00000133731        234        259        326        268        348
ENSG00000133739        219        184        179        117        181
ENSG00000133740         85         68         70         36         83
ENSG00000133742          0          0          0          0          0
ENSG00000133773        244        227        277        182        363
ENSG00000133789       2989       3818       3371       2992       2689
ENSG00000133794        221        363        256        219        276
ENSG00000133800          3          5          8          9          5
ENSG00000133805        616        584       1017        672        475
ENSG00000133808          2          1          3          3          3
ENSG00000133812       2260       1878       2999       1846       2946
ENSG00000133816        907       1463       1168       1128       1529
ENSG00000133818       2036       2647       3301       3121       2586
ENSG00000133835       2340       2678       2735       1779       2865
ENSG00000133858       1693       1934       2327       1601       2494
ENSG00000133863          0          4          7          1          0
ENSG00000133872       2618       1999       3494       1926       3141
ENSG00000133874        202        145        135         46        129
ENSG00000133878          1          1          1          1          2
ENSG00000133884       1134        953       1341        697       1351
ENSG00000133895        730        707        747        413        734
ENSG00000133935        382        254        490        288        475
ENSG00000133937          4          5          4          1          0
ENSG00000133943        804        382        805        271        696
ENSG00000133958          8         15         16          9         26
ENSG00000133961       1432       1421       1872       1148       1893
ENSG00000133962          0          0          0          1          1
ENSG00000133980          0          0          0          0          0
ENSG00000133983        130        118        124        102        155
ENSG00000133985          2          1          6          2          6
ENSG00000133997        231        178        260        170        279
ENSG00000134001        927        945       1110        722       1249
ENSG00000134007          0          0          1          0          0
ENSG00000134013       2977       1187       3530        921       5134
ENSG00000134014        552        512        631        416        736
ENSG00000134020          5         11         14         13         11
ENSG00000134028          7          4          3          2          1
ENSG00000134030       1832       1812       2534       1348       2183
ENSG00000134042          5          5          2          3          0
ENSG00000134046        973       1335       1386       1228       1470
ENSG00000134049        360        316        315        303        428
ENSG00000134056        226        288        283        252        258
ENSG00000134057         97        118        153         97        109
ENSG00000134058        356        432        557        402        496
ENSG00000134061          0          0          0          0          0
ENSG00000134070         56         20         69         15        101
ENSG00000134072         55         43         63         37         34
ENSG00000134077        525        469        637        366        691
ENSG00000134086        661        539        732        436        759
ENSG00000134107        547        205        289         78        666
ENSG00000134108       2063       2175       2578       1901       2634
ENSG00000134109       1132        966       1116        844       1177
ENSG00000134115          0          1          2          2          0
ENSG00000134121        114        316         72        119         79
ENSG00000134138        670        325       1228        354        726
ENSG00000134146         75         77         82         59         81
ENSG00000134152        395        365        354        262        372
ENSG00000134153        799        852       1182        874       1162
ENSG00000134160          0          0          0          0          0
ENSG00000134183         13         10          7          0         17
ENSG00000134184         26         20         26         10         15
ENSG00000134186       1006       1171       1085        703       1430
ENSG00000134193          0          0          0          0          0
ENSG00000134198         15          6         21          7          3
ENSG00000134200          0          0          0          0          0
ENSG00000134201        670        391        308        110        445
ENSG00000134202        743        530       1294        609       1096
ENSG00000134207          0          0          0          0          1
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ENSG00000134222         53         79         84         46         98
ENSG00000134240          0          0          0          0          0
ENSG00000134242          1          5          3          9          4
ENSG00000134243       1419       4541       2944       7427       2536
ENSG00000134245        171        222        324        143        376
ENSG00000134247       2333       1210       1649        443       1296
ENSG00000134248        533        602        636        414        666
ENSG00000134249          0          0          0          0          0
ENSG00000134250       9063       7965      13444       7573      12164
ENSG00000134253        222         45        275         51        206
ENSG00000134255        771        567       1041        536        884
ENSG00000134256          9          3          2          0          2
ENSG00000134258          2          0          5          0          1
ENSG00000134259         38         16        132         17         48
ENSG00000134262        134        127        161         91        137
ENSG00000134265        425        494        492        384        480
ENSG00000134278        490        444        669        330        893
ENSG00000134283        791        722        920        611       1006
ENSG00000134285        258        235        265        178        234
ENSG00000134287       2109       2007       2462       1840       2202
ENSG00000134291        517        332        726        346        756
ENSG00000134294      13429      20241      13128      23802      15091
ENSG00000134297         37         32         44         25         42
ENSG00000134308       7162       6425       7345       4964       7651
ENSG00000134313       3350       2604       3926       2206       4055
ENSG00000134317         31         14         91         35         77
ENSG00000134318       3198       5277       3938       3882       3632
ENSG00000134321         27          0          9          2          1
ENSG00000134323          0          0          0          0          0
ENSG00000134324       4360       4498       3985       4494       3718
ENSG00000134326         11          6          2          1          2
ENSG00000134330        632        572        737        526        778
ENSG00000134333      11177      14263      12813      10820      11718
ENSG00000134339          0          0          1          2          0
ENSG00000134343         27         48         55         59         11
ENSG00000134352      40830      31216      46789      31454      34568
ENSG00000134363       3102        674       7670       1042       5720
ENSG00000134365          0          0          1          1          0
ENSG00000134369       3351       2348       4959       3094       4059
ENSG00000134371        862        861        974        738        994
ENSG00000134375        641        638        795        468        755
ENSG00000134376          5          2         17          0         12
ENSG00000134389          0          0          0          0          0
ENSG00000134398          0          0          6          2          1
ENSG00000134419       1766       1646       1779        963       1744
ENSG00000134438          0          0          0          0          0
ENSG00000134440       2734       2567       3021       1875       3184
ENSG00000134443          0          0          0          0          0
ENSG00000134444        642        553        709        449        713
ENSG00000134452       1556       1486       1784       1048       1676
ENSG00000134453       1277       1252       1478        982       1537
ENSG00000134460          2          0          2          1          3
ENSG00000134461         99         90        100         48         96
ENSG00000134463         65         94         28         15         31
ENSG00000134470        550        645        474        375        470
ENSG00000134480        324        398        374        243        493
ENSG00000134489          0          1          2          3          2
ENSG00000134490        109        112        127         93        137
ENSG00000134504        273        249        315        216        267
ENSG00000134508        647        837        903        839        864
ENSG00000134516        188        143        272         91        182
ENSG00000134531       3736       4852       4569       5199       4036
ENSG00000134532        107        145        138        141        163
ENSG00000134533          4          8          3          2         16
ENSG00000134538          0          0          0          0          0
ENSG00000134539          2          3         23          7          8
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ENSG00000134551          5          2          6          2          4
ENSG00000134569         95         54         55         19        141
ENSG00000134571          0          0          0          0          0
ENSG00000134574       1572       1131       1332        621       1214
ENSG00000134575        347        393        625        462        552
ENSG00000134588          0          0          0          0          0
ENSG00000134590       3915       3974       5024       2916       4254
ENSG00000134594         15          6         17          2         15
ENSG00000134595          3          4          4          0          1
ENSG00000134597        288        220        361        185        387
ENSG00000134602         50         59         34         41         92
ENSG00000134612          0          0          0          0          0
ENSG00000134627        100         93         84         84         83
ENSG00000134640          0          0          0          0          0
ENSG00000134644       2436       2155       2343       1493       2804
ENSG00000134668        583        484        624        361        537
ENSG00000134684       1343        796       1806        568       1993
ENSG00000134686       1491       3276       1784       2747       1951
ENSG00000134690         30         49         32         17         21
ENSG00000134697        792       1125        894        683       1128
ENSG00000134698        595        589        687        522        683
ENSG00000134709          0          7          2          4          0
ENSG00000134716         45         34         36         10         22
ENSG00000134717        765        723        910        576        906
ENSG00000134744        863        605       1115        491       1262
ENSG00000134748        467        372        623        300        623
ENSG00000134755          1          0         11          0          8
ENSG00000134757          1          0          1          0          0
ENSG00000134758        114        108        125         70        147
ENSG00000134759       1997       1548       2248       1227       2547
ENSG00000134760          0          0          1          0          0
ENSG00000134762         52         58        194        355        315
ENSG00000134765          0          0          0          0          0
ENSG00000134769        403        209        361        127        577
ENSG00000134775       2136       2228       4404       2241       3326
ENSG00000134779       2030       1508       3550       1508       2707
ENSG00000134780        149         74        207         50        141
ENSG00000134802        535        337        405        235        368
ENSG00000134809        148        147        211        110        268
ENSG00000134812          0          0          0          0          0
ENSG00000134815        242        174        231         86        307
ENSG00000134817          0          0          0          0          0
ENSG00000134824       1945        726       2345       1141       1754
ENSG00000134825        717        599        596        375        549
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ENSG00000134830          0          2          1          1          1
ENSG00000134851       1671       2299       1817       1558       1708
ENSG00000134852        923        794       1016        498        994
ENSG00000134853      12020      12649      17267      16939      13591
ENSG00000134864         60         60         68         45         57
ENSG00000134871       2917       5145       3264       2824       4344
ENSG00000134873          1          0          0          0          0
ENSG00000134874       1651       1186       1989        887       2225
ENSG00000134882       1122       1158       1607        924       1549
ENSG00000134884       2212       2018       2363       1411       2337
ENSG00000134897        450        389        527        400        471
ENSG00000134899        342        303        391        278        440
ENSG00000134900       1744       1449       1815       1180       2059
ENSG00000134901        266        219        344        178        334
ENSG00000134905        818       1046        805        551       1034
ENSG00000134909        433        308        511        224        587
ENSG00000134910       3338       2708       4023       2509       3895
ENSG00000134917       4735       6307       6969       2542       9451
ENSG00000134940          2          0          1          2          0
ENSG00000134954       1213       1008        949        746       1203
ENSG00000134955          0          2          3          0          5
ENSG00000134962          0          1          0          2          0
ENSG00000134970       1776       1600       2132       1726       1884
ENSG00000134982       1149       1246       1253        845       1425
ENSG00000134986        851        414        945        285        701
ENSG00000134987       1297        738       1280        491       1545
ENSG00000134996        433        395        432        268        380
ENSG00000135002        497        544        777        495        714
ENSG00000135018       1940       1901       2470       1646       2376
ENSG00000135040        430        316        507        235        539
ENSG00000135045         80         70         72         36        100
ENSG00000135046       7825       9260      10396       8597       8281
ENSG00000135047       4253       4370       5582       4026       7229
ENSG00000135048        579        828        839        934        908
ENSG00000135049        193        194        282        191        260
ENSG00000135052       1957       1419       2674       1298       2952
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ENSG00000135069       1226        533       1516        357        793
ENSG00000135070        622        728        773        675        708
ENSG00000135074        611        600        767        756        749
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ENSG00000135090       1143       1490       1448       1003       1488
ENSG00000135093        395        231        373        190        473
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ENSG00000135108       1161        844       1256        661       1223
ENSG00000135111       2361       1538       2193        974       2778
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ENSG00000135124        444        351        546        273        392
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ENSG00000135144          1          1          0          0          0
ENSG00000135148       1054       1006       1189        858       1354
ENSG00000135164       1009        966       1544        939       1372
ENSG00000135175          3          0          1          1          0
ENSG00000135185        296        297        248        227        237
ENSG00000135205         95         88         97         88        105
ENSG00000135211        325        310        269        235        210
ENSG00000135213       1219       1121       1430        793       1438
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ENSG00000135241        840       1075        854        746        962
ENSG00000135245        202        160        133         71        182
ENSG00000135248          1          2          3          3          4
ENSG00000135249        355        274        313        207        421
ENSG00000135250       1008        670       1061        583       1223
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ENSG00000135269       1062       1382       1821        773       2118
ENSG00000135272       1044       1265       1262       1080       1393
ENSG00000135297        390        300        350        181        438
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ENSG00000135315        361        270        403        182        497
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ENSG00000135317        985        958       1325        945       1337
ENSG00000135318       5201       2991       5377       1374       5321
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ENSG00000135334        716        689        940        569       1020
ENSG00000135336        629        564        852        491        822
ENSG00000135338        247        184        269        169        293
ENSG00000135341       1374       1174       1744        979       2019
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ENSG00000135362         49        142         73         99         61
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ENSG00000135365       1411       1015       1541        928       1769
ENSG00000135372        711        698        890        500        846
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ENSG00000135390       1856       1749       2376       1133       2260
ENSG00000135392        366        266        421        211        504
ENSG00000135404      22780      18469      26802      14327      31498
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ENSG00000135407         69         82        107         76         96
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ENSG00000135414        686        436        690        307        748
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ENSG00000135424       2661       1510       3550       1487       2042
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ENSG00000135441        105         90         87         46         67
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ENSG00000135452        400        397        441        355        473
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ENSG00000135457        546        406        659        408        720
ENSG00000135469        133        123        137         89        131
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ENSG00000135473        454        550        587        307        489
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ENSG00000135503        678        713        760        555        753
ENSG00000135506       5456       4879       7382       4047       7282
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ENSG00000135521        244        297        355        252        421
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ENSG00000135535       7164       5428       7800       4774       8281
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ENSG00000135540        538        748        567        414        792
ENSG00000135541        428        296        599        243        643
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ENSG00000135587         76         71         93         54        102
ENSG00000135596       1234       1535       1327        972       1255
ENSG00000135597        418        337        436        263        564
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ENSG00000135605         18         19         38         28         27
ENSG00000135617        232        166        170        113        215
ENSG00000135622        330        227        301        177        324
ENSG00000135624       2435       2469       2739       1572       2957
ENSG00000135625          0          0          0          0          0
ENSG00000135631       1938       1647       2019       1233       1849
ENSG00000135632        497        383        519        249        517
ENSG00000135636          2          1          2          3          8
ENSG00000135637        151        105        128         64        164
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ENSG00000135655        684        642        801        509        890
ENSG00000135677       8485       6480      12843       6843      13484
ENSG00000135678        531        598        412        811        557
ENSG00000135679       2650       1471       3097       1153       3041
ENSG00000135686       1647       1619       1580       1148       1623
ENSG00000135697          4          1          5          0          3
ENSG00000135698        294        349        311        163        376
ENSG00000135702          0          0          0          0          1
ENSG00000135709       1546        930       1549        904       1515
ENSG00000135720       3645       3038       3741       2210       4021
ENSG00000135722         98         85         81         49         75
ENSG00000135723        442        223        384        114        635
ENSG00000135736        275        253        353        145        288
ENSG00000135740        109         91        130         53        164
ENSG00000135744        250         55       1575        478       1659
ENSG00000135747         55         43         46         48         51
ENSG00000135749        576        327        842        293        739
ENSG00000135750         38         62         14         10         97
ENSG00000135763        136        152        175        106        180
ENSG00000135766       1606       1458       1484        983       1449
ENSG00000135773          1          1          6          3          3
ENSG00000135775        447        317        535        281        640
ENSG00000135776        279        283        310        239        296
ENSG00000135778        934        541        798        345        778
ENSG00000135801        266        319        328        243        381
ENSG00000135821       5065      38018       4976      22220       5275
ENSG00000135823        726        660        803        726        761
ENSG00000135824          0          0          0          0          0
ENSG00000135828        402        345        579        326        213
ENSG00000135829       3796       3453       3976       2143       4275
ENSG00000135835        396        327        428        241        411
ENSG00000135837       2254       2040       2933       1662       3103
ENSG00000135838         42         70         44         44         73
ENSG00000135842       2688       1381       3388       1345       1794
ENSG00000135845        253        293        330        264        379
ENSG00000135847        838        552        847        396        945
ENSG00000135862      23163      39551      30723      27708      32147
ENSG00000135870        657        595        675        501        792
ENSG00000135898          0          0          0          0          0
ENSG00000135899        461        539        533        499        549
ENSG00000135900        328        281        403        242        384
ENSG00000135902          0          0          0          0          0
ENSG00000135903          0          1          0          0          0
ENSG00000135905        585        608        404        251        629
ENSG00000135912        230        185        206        134        280
ENSG00000135913        119         83        140         53        147
ENSG00000135914          8          4         21         11          8
ENSG00000135916       3637       3036       4015       2235       4861
ENSG00000135917         36         90         34         32         26
ENSG00000135919       8598       3953      21841       8228      10311
ENSG00000135924       2285       1685       2210       1093       2252
ENSG00000135925          0          0          0          0          0
ENSG00000135926       4752       5602       4849       4643       4747
ENSG00000135929        991        735       1212        723       1273
ENSG00000135930        943       1024       1327        886       1248
ENSG00000135931        573        518       1137       1260        968
ENSG00000135932       1752       1754       1672       1298       1678
ENSG00000135940        970       1004       1295        729       1218
ENSG00000135945        426        319        466        251        523
ENSG00000135951         31         25         38         22         48
ENSG00000135953        182        133        258        141        193
ENSG00000135956       1991       2072       2448       1829       2611
ENSG00000135960          0          0          0          0          0
ENSG00000135966        652        637        658        435        714
ENSG00000135968       1363       1107       1580        814       1978
ENSG00000135972        217        157        250        147        274
ENSG00000135973          1          3          1          0          0
ENSG00000135974        531        451        649        345        637
ENSG00000135976        451        268        573        198        568
ENSG00000135999        610        485        746        392        751
ENSG00000136002         25         26         38         19         25
ENSG00000136003       3019       2653       2978       1742       3180
ENSG00000136010       2201       1632       2877       1227       2259
ENSG00000136011          2          3          4          5          4
ENSG00000136014        212        223        216        190        174
ENSG00000136021       1164        963       1356        817       1386
ENSG00000136026       4396       2977       5131       2673       5909
ENSG00000136040       4004       3067       5209       2839       7044
ENSG00000136044       2495       2012       3053       1962       2361
ENSG00000136045        874        859       1057        690       1009
ENSG00000136048       5018       3029       8614       4481       6406
ENSG00000136051       2077       2174       1884       1489       2408
ENSG00000136052        391        177        508        161        442
ENSG00000136059        182        158        220         96        147
ENSG00000136068       1719       1623       2108       1315       1339
ENSG00000136098        184        210        293        208        240
ENSG00000136099          0          0          0          0          0
ENSG00000136100        694        720        900        675        820
ENSG00000136104        387        280        286        175        315
ENSG00000136108        483        351        446        235        522
ENSG00000136110          0          0          0          0          0
ENSG00000136111        556        619        577        615        748
ENSG00000136114         66        109        201        115         77
ENSG00000136122         54         52         59         47         60
ENSG00000136141        733        393        623        251        702
ENSG00000136143        696        624        847        493        857
ENSG00000136144        894        690        982        585       1383
ENSG00000136146        400        384        480        348        452
ENSG00000136147        473        488        565        373        610
ENSG00000136149       1187       1137       1268        753       1161
ENSG00000136152        567        516        615        344        641
ENSG00000136153       1744       1704       4381       2737       2806
ENSG00000136155          0          0          0          0          0
ENSG00000136156      11328      15289      15515      12515      13079
ENSG00000136158        207        258        209        201        207
ENSG00000136159        187        199        219        110        212
ENSG00000136160        480        886        233        159       1182
ENSG00000136161        298        335        325        213        304
ENSG00000136167         18         10          8          1          0
ENSG00000136169        443        392        534        331        525
ENSG00000136193       4130       4435       4815       3676       4682
ENSG00000136197          3          5         10          6         10
ENSG00000136205       8537       5443      13114       7094       8862
ENSG00000136206          9         10         31         11         13
ENSG00000136213        320        392        390        251        396
ENSG00000136231        157        158        148         91        485
ENSG00000136235      32622      19292      35108      16177      35792
ENSG00000136237         18         37         15        143         38
ENSG00000136238       4458       4762       5257       3957       5206
ENSG00000136240       4928       3867       5233       3299       4861
ENSG00000136243        261        212        266        196        279
ENSG00000136244        170         39        143         57        177
ENSG00000136247        466        451        522        326        563
ENSG00000136250          0          0          0          0          0
ENSG00000136261        452        350        411        137        548
ENSG00000136267          0          0         21          1         25
ENSG00000136270        538        688        512        394        552
ENSG00000136271        756        772        760        489        855
ENSG00000136273        219        186        257        150        322
ENSG00000136274        559        462        928        354        774
ENSG00000136275          6          1          5          3          0
ENSG00000136279       1993       1565       2178       1193       2138
ENSG00000136280        677        621        709        414        737
ENSG00000136286          0          0          0          0          0
ENSG00000136295       3090       1421       2489        781       3786
ENSG00000136297          0          0          0          0          0
ENSG00000136305          0          0          0          0          0
ENSG00000136315          0          0          0          0          0
ENSG00000136319        237        159        269        138        328
ENSG00000136327          0          0          0          1          0
ENSG00000136352          0          0          0          0          0
ENSG00000136367         62         30         88         31         60
ENSG00000136371         12          9         24          6         12
ENSG00000136378       1168       1199       2036       1930       1193
ENSG00000136379        370        494        432        390        477
ENSG00000136381       1142        963       1315        797       1307
ENSG00000136383          9        169         21         98         17
ENSG00000136404         75         61        108         81        109
ENSG00000136425         55         49         62         22         51
ENSG00000136436       1648       3061       2522       3662       2468
ENSG00000136444        546        464        517        248        487
ENSG00000136448       2997       2813       3550       1902       3895
ENSG00000136449         34         27         31         20         16
ENSG00000136450       1964       1656       2211       1289       2399
ENSG00000136451       1634       1533       1850       1223       2042
ENSG00000136457         13         16         18          5         14
ENSG00000136463        234        204        297        160        324
ENSG00000136478       1546       3201       2442       4131       2213
ENSG00000136485       1773       1546       1878       1162       2093
ENSG00000136487          0          0          0          0          0
ENSG00000136488          0          0          0          0          0
ENSG00000136490         64         57         71         34         86
ENSG00000136492         65         69         92         53         67
ENSG00000136504        677        502        801        421        804
ENSG00000136514         86         45         94         44         35
ENSG00000136518        427        366        397        230        477
ENSG00000136521        781        666        927        576        930
ENSG00000136522        327        323        383        252        378
ENSG00000136527       1404       1231       1684        826       1569
ENSG00000136531        499        191        576        215        232
ENSG00000136535          0          1          0          0          0
ENSG00000136536       1501       1137       1768       1078       2020
ENSG00000136541          0          0          0          2          0
ENSG00000136542       2137       1433       2903       1223       4146
ENSG00000136546       2621       4410       3187       5322       1716
ENSG00000136560        960       1236       1117        997       1278
ENSG00000136573          0          2          0          0          0
ENSG00000136574          0          0          0          0          0
ENSG00000136603        734        580       1084        538       1181
ENSG00000136628       2969       1938       3539       1759       3096
ENSG00000136630        274        283        333        253        343
ENSG00000136631        712        605        915        469        899
ENSG00000136634          0          0          0          0          0
ENSG00000136636       1791       1328       1867       1051       2292
ENSG00000136643        777        548        844        443        988
ENSG00000136653        197        179        269        172        201
ENSG00000136682        629        561        652        441        638
ENSG00000136688          0          0          0          0          0
ENSG00000136689          3          0          3          0          4
ENSG00000136694          0          0          0          0          0
ENSG00000136695          0          0          0          0          0
ENSG00000136696          0          0          0          0          0
ENSG00000136697          0          0          0          0          0
ENSG00000136698          0          0          0          0          0
ENSG00000136699       1288       1075       1377        757       1365
ENSG00000136709        912        925        919        663       1093
ENSG00000136710        641        556        699        447        824
ENSG00000136715        719        541        813        416        843
ENSG00000136717       1073        789        846        343        949
ENSG00000136718        476        535        531        339        534
ENSG00000136720       1122       1935       1625        910       1448
ENSG00000136731       2837       2305       3578       1709       2866
ENSG00000136732       1340       1142       1671        645       1856
ENSG00000136738        788        640        990        507       1121
ENSG00000136750          0          0          0          0          0
ENSG00000136754       1174       1086       1186        894       1162
ENSG00000136758       3176       2810       3709       2305       4004
ENSG00000136770        496        463        632        332        722
ENSG00000136783        245        274        293        273        253
ENSG00000136802       1419       1060       1586        830       1587
ENSG00000136807        844        910        955        610        885
ENSG00000136810       2908       2904       3444       1947       3675
ENSG00000136811        503        402        553        304        681
ENSG00000136813       2423       2589       2872       2184       3126
ENSG00000136816        709        669        946        654        906
ENSG00000136819        780        774        935        603        967
ENSG00000136824        542        472        690        348        610
ENSG00000136826       1804       1108       2166        584       1284
ENSG00000136827        890        875       1036        782       1052
ENSG00000136828        117         64        131         65        138
ENSG00000136830      13971      16758      16754      14930      17775
ENSG00000136834          0          1          0          0          0
ENSG00000136839          0          0          0          0          0
ENSG00000136840        440        505        354        227        409
ENSG00000136842        134         71         87         59         45
ENSG00000136848       1750       1196       1900        768       1862
ENSG00000136854       1231       1096       1702        935       1839
ENSG00000136856        145        134        147         73        153
ENSG00000136859       8137       4451       9008       3065      11452
ENSG00000136861       1698       1096       2459       1190       2326
ENSG00000136866         70         36         64         33         77
ENSG00000136867          5          4          8          3          3
ENSG00000136868        832       1062        989        773       1237
ENSG00000136869        190         99        370        339        239
ENSG00000136870        385        241        398        227        422
ENSG00000136872          4          3          2          2          2
ENSG00000136874        279        266        397        228        425
ENSG00000136875        478        451        573        300        657
ENSG00000136877        852       1161       1014        871        945
ENSG00000136878        594        453        639        306        651
ENSG00000136881          0          0          0          0          0
ENSG00000136883          2          0          0          0          0
ENSG00000136888       1158        916       1183        651       1452
ENSG00000136891        699        645        679        387        762
ENSG00000136895         63         45         66         29         53
ENSG00000136897        257        280        261        186        315
ENSG00000136908        373        395        433        252        449
ENSG00000136918          1          0          1          0          1
ENSG00000136925        353        222        399        179        411
ENSG00000136928         44        256        205        125         36
ENSG00000136929          0          0          0          0          0
ENSG00000136930       2310       1761       2468       1188       2527
ENSG00000136931          0          0          0          0          0
ENSG00000136932        156        134        175         83        198
ENSG00000136933        442        430        366        248        387
ENSG00000136935        727        600        818        439        865
ENSG00000136936        187        144        262        164        253
ENSG00000136937        894        742       1034        424       1085
ENSG00000136938       2023       2243       2764       1701       2863
ENSG00000136939          0          0          0          0          0
ENSG00000136940        521        395        455        368        501
ENSG00000136942       5834       6022       5465       2501       5516
ENSG00000136943          0          3          2          2          3
ENSG00000136944          0          0          0          0          0
ENSG00000136950        386        347        402        230        443
ENSG00000136960        249         78        803        251        680
ENSG00000136982        119        103         58         32         77
ENSG00000136986       1243       1374       1219        953       1461
ENSG00000136997        588        838        604        546        663
ENSG00000136999        615         68       1022        120        504
ENSG00000137033        870        863       1051        431        768
ENSG00000137038        361        384        346        195        365
ENSG00000137040        570        403        526        321        525
ENSG00000137054        530        493        483        220        470
ENSG00000137055        611        501        741        455        710
ENSG00000137070        358        326        378        165        363
ENSG00000137073        623        634        972        455        996
ENSG00000137074        483        332        516        298        475
ENSG00000137075        882        784        937        747        963
ENSG00000137076      16161      18903      19427      14550      18631
ENSG00000137077          0          0          0          0          0
ENSG00000137078          1          1          3          1          1
ENSG00000137080          1          0          0          0          0
ENSG00000137090          0          0          0          0          0
ENSG00000137094        411        348        376        159        470
ENSG00000137098         33         18         44         16         36
ENSG00000137100        892        750        963        499        981
ENSG00000137101         38         29         62         48         65
ENSG00000137103        487        411        626        397        649
ENSG00000137106       1078       1060       1384        780       1347
ENSG00000137124        405        715        712        673        448
ENSG00000137133        143         93        165        107         99
ENSG00000137135         15         13         26         18         32
ENSG00000137142          0          1          0          0          0
ENSG00000137145       1551       1216       1679       1179       1644
ENSG00000137154      29005      28917      29702      14775      27520
ENSG00000137161        622        502        616        358        634
ENSG00000137166        338        305        391        243        427
ENSG00000137168        252        196        307        118        350
ENSG00000137171        362        271        413        185        438
ENSG00000137177       3715       3724       4794       3186       4470
ENSG00000137185        138         87        130         72        152
ENSG00000137193       1182        659       1016        259       1307
ENSG00000137197          0          0          0          0          0
ENSG00000137198        158        105        249        224        240
ENSG00000137200       1367       1143       1318        868       1428
ENSG00000137203         23         18         74         11        178
ENSG00000137204          1          0          0          0          0
ENSG00000137207       2232       2034       2508       1526       2723
ENSG00000137210        441        390        503        331        486
ENSG00000137216        888        785       1062        509       1327
ENSG00000137218         79         84        102         52         75
ENSG00000137221        613        565        731        428        695
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ENSG00000137259          0          0          1          0          0
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ENSG00000137265        143        347        107        239         74
ENSG00000137266        255         86        200         52        283
ENSG00000137267        486        601        673        233        566
ENSG00000137269         77         92         74         75        103
ENSG00000137270          0          0          0          0          0
ENSG00000137273       2979       2190       3220        941       3181
ENSG00000137274        130         88        130         51        147
ENSG00000137275        991        852       1090        637       1197
ENSG00000137285        291        347        427        138        369
ENSG00000137288        444        327        419        166        395
ENSG00000137309       3896       2579       4152       1986       3750
ENSG00000137310        165        115        179         76        134
ENSG00000137312       3171       3247       3844       2381       3907
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ENSG00000137321          0          0          0          0          0
ENSG00000137331        149         37        152         49        372
ENSG00000137332          0          0          0          0          0
ENSG00000137337        485        408        524        312        570
ENSG00000137338        155        146        168        104        213
ENSG00000137343        220        117        248         78        250
ENSG00000137345          0          0          0          0          0
ENSG00000137364        374        276        452        197        438
ENSG00000137384          0          0          0          0          0
ENSG00000137392          0          0          0          0          0
ENSG00000137393         32        155         86        148         67
ENSG00000137394          0          0          0          0          0
ENSG00000137397          0          0          0          0          0
ENSG00000137403          0          0          0          0          0
ENSG00000137404        162         95        233         91        143
ENSG00000137409       4374       3679       5146       2611       5099
ENSG00000137411        357        355        358        196        393
ENSG00000137413        410        405        437        297        432
ENSG00000137414       1658       1453       1860       1415       2020
ENSG00000137434         10          5          4          2          6
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ENSG00000137441          0          0          0          0          0
ENSG00000137449        374        371        544        364        532
ENSG00000137460         21         20         17          5         22
ENSG00000137462         51         16         19         10         27
ENSG00000137463         72         49        151        133         97
ENSG00000137473          0          0          1          0          1
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ENSG00000137478        477        443        641        438        782
ENSG00000137486        318        222        422        208        123
ENSG00000137491          0          1          0          0          1
ENSG00000137492        945        841        978        625        933
ENSG00000137494        259        213        387        204        367
ENSG00000137496         56         57        115         56         96
ENSG00000137497       4831       3397       5422       2445       5054
ENSG00000137500        962        739       1108        487       1188
ENSG00000137501        963        438       1342        325       1615
ENSG00000137502        820        764       1135        552        796
ENSG00000137504       1332       1181       1197        765       1478
ENSG00000137507       3648       2738       2487       1493       3678
ENSG00000137509       2372       1991       3545       2517       4323
ENSG00000137513        177        149        214        102        200
ENSG00000137522        349        273        432        219        382
ENSG00000137547        385        400        356        276        355
ENSG00000137558          0          3          0          0          0
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ENSG00000137563        206        225        323        241        252
ENSG00000137571          1          5          0          1          1
ENSG00000137573       8055       9488      36530      20497       7428
ENSG00000137574        346        346        427        209        413
ENSG00000137575       6861       5195       6960       4089       8466
ENSG00000137601        738        632        880        451       1022
ENSG00000137628        536        382        556        332        589
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ENSG00000137672        204        654        371        742        283
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ENSG00000137692        299        304        320        218        358
ENSG00000137693       3728       3852       3976       2915       4310
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ENSG00000137700        203        150        212        103        190
ENSG00000137707          1          1          0          3          1
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ENSG00000137710       2026       1829       2207       1338       2638
ENSG00000137713        714        648        941        463        915
ENSG00000137714        234        227        241        158        229
ENSG00000137720        138        145        176         97        187
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ENSG00000137760        204        170        221        126        175
ENSG00000137764        569        486        547        410        534
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ENSG00000137767        478        998        705        681        821
ENSG00000137770        485        372        569        363        537
ENSG00000137776       1233       1269       1270        839       1652
ENSG00000137801      33528      60378      58310     124180      37996
ENSG00000137802        558        618        589        352        627
ENSG00000137804        104        112        124         82        134
ENSG00000137806        210        217        209        171        257
ENSG00000137807         80        110        130         80        121
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ENSG00000137809       2863        937       2332        464        639
ENSG00000137812         29         45         50         30         35
ENSG00000137814        357        307        413        229        471
ENSG00000137815       1533       1313       1909       1034       1876
ENSG00000137817        595        583        677        406        684
ENSG00000137818      21662      22205      24061      12123      19204
ENSG00000137819         58         79        255        105        292
ENSG00000137821        268        146        444        164        325
ENSG00000137822        603        500        593        304        694
ENSG00000137824        585        580        710        491        637
ENSG00000137825         15          8         14          4         22
ENSG00000137831       2657       1512       3854       1912       4430
ENSG00000137834        306        175        402        243        277
ENSG00000137841          4          2          5          0          4
ENSG00000137842         97        107        154        127        144
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ENSG00000137845       3449       2850       3877       2596       4356
ENSG00000137857         33         29         35         12         20
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ENSG00000137869         35        103         39         47         79
ENSG00000137871        642        562        858        425        865
ENSG00000137872        474        138        489        148        494
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ENSG00000137877          8         14         14          9         16
ENSG00000137878          0          0          0          0          0
ENSG00000137880         51        110         77         89         59
ENSG00000137936        572        533        704        405        601
ENSG00000137941        570        498        594        282        556
ENSG00000137942        488        449        613        507        335
ENSG00000137944        356        364        859        521        501
ENSG00000137947        324        294        394        227        398
ENSG00000137948          0          0          0          0          0
ENSG00000137955        400        425        447        281        505
ENSG00000137959         73        130         40         96         78
ENSG00000137960          7         15         19         43          6
ENSG00000137962       2116       3549       3963       4542       2607
ENSG00000137965        342        149        285        106        312
ENSG00000137968          4          0          4          2          3
ENSG00000137970       6572       5984       6493       3535       5976
ENSG00000137975        829        375        629        328        407
ENSG00000137976          1          0          0          0          0
ENSG00000137992        612        597        740        491        740
ENSG00000137996        516        487        645        424        600
ENSG00000138002        675        462        715        277        679
ENSG00000138018        323        251        318        194        356
ENSG00000138028        247        387        425        270        128
ENSG00000138029       2360       2349       2434       1827       2717
ENSG00000138030         13         36         23         31         19
ENSG00000138031        768        802        860        836       1159
ENSG00000138032        696       1107        674        716        619
ENSG00000138035        336        377        411        271        481
ENSG00000138036        273        348        497        326        405
ENSG00000138039          2          8         14         12         20
ENSG00000138041       1652       1430       1813       1118       2139
ENSG00000138050        184        132        156         75        154
ENSG00000138061       1250       1963       1875       1023       2691
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ENSG00000138069       3271       3320       3467       2323       4085
ENSG00000138071       5228       5139       5518       4077       4742
ENSG00000138073       1302       2896       1393       1487       1145
ENSG00000138074        248        623        298        391        383
ENSG00000138075          0          0          0          0          0
ENSG00000138078       1452        865       1790        571       1820
ENSG00000138079          0          1          2          2          5
ENSG00000138080      14497      16057      12635       8062      10900
ENSG00000138081        707        594        840        417        969
ENSG00000138083          0          0          2          0          0
ENSG00000138085       1553       1397       1621       1068       1778
ENSG00000138092        125         83        166         62        118
ENSG00000138095       2177       1749       2412       1330       2655
ENSG00000138100          1          0          0          1          1
ENSG00000138101        112         74        131         40        148
ENSG00000138107       2839       2971       3172       2003       3083
ENSG00000138109          0          1          0          0          0
ENSG00000138111         86         83         95         54         95
ENSG00000138115          1          1          2          1          0
ENSG00000138119      11544      11206      15744      10210      19573
ENSG00000138131        645        462       1252        647        829
ENSG00000138134        178        119        278         73        441
ENSG00000138135         54         13         69          7         79
ENSG00000138136          0          0          0          0          0
ENSG00000138138        914        867       1152        750       1235
ENSG00000138152          0          0          0          0          0
ENSG00000138160        218        117        270         87        154
ENSG00000138161         26         16         32         12         12
ENSG00000138162        103        116        176         93        192
ENSG00000138166        211        342        298        417        322
ENSG00000138172       1217       1092       1291        727       1000
ENSG00000138175        506        509        641        362        660
ENSG00000138180         47         61         46         33         46
ENSG00000138182        181        142        196        105        234
ENSG00000138185       1518        960       1720        898       1506
ENSG00000138190        264        224        369        299        321
ENSG00000138193        230        280        410        288        222
ENSG00000138207          8         13          5          3          3
ENSG00000138231        269        255        304        161        264
ENSG00000138246       3500       3043       5248       2750       4927
ENSG00000138271          1          1          2          0          0
ENSG00000138279       1810       1455       2270       1428       1968
ENSG00000138286        606        458        881        405        723
ENSG00000138293       4336       3458       4422       2604       5050
ENSG00000138294          0          1          0          1          0
ENSG00000138297        708        707        818        530        870
ENSG00000138303        487        390        517        305        514
ENSG00000138308          0          0          2          0          0
ENSG00000138311        115         47        181         55        165
ENSG00000138315          1          1          0          0          1
ENSG00000138316       1327        207       1521        118       1962
ENSG00000138326      11020      10824      13637       6907      13717
ENSG00000138336         73         67        118         31         99
ENSG00000138346         75         75         56         43         78
ENSG00000138347          5          5         24          7         33
ENSG00000138356       1394       5035       2462       3415       4869
ENSG00000138363       1088       1176       1319        775       1388
ENSG00000138375        673        484        806        367        798
ENSG00000138376        113         97         99         53         75
ENSG00000138378          3          3          9          3         16
ENSG00000138379          8         17        129        132        129
ENSG00000138380        278        163        376        149        295
ENSG00000138381        747        749       1175        882       1221
ENSG00000138382        343        381        290        267        387
ENSG00000138385       1175       1736       1533       1425       1954
ENSG00000138386        715        405        582        227        681
ENSG00000138395         72         66        165         42        228
ENSG00000138398       1161       1052       1565        865       1782
ENSG00000138399        175        151        196         91        271
ENSG00000138400         40         12         36         15         27
ENSG00000138411         16         13         36         15         50
ENSG00000138413       1903       1543       1899       1015       1522
ENSG00000138430       1030        826       1224        653       1124
ENSG00000138433        696        561       1045        539       1108
ENSG00000138434       3697       2669       3514       2157       4125
ENSG00000138435          6          1          7          0          4
ENSG00000138439        175         83        199        124        190
ENSG00000138442        439        414        423        244        546
ENSG00000138443       1127        743       1445        725       1367
ENSG00000138448       4635       3772       6131       3828       5947
ENSG00000138449       4876       2966       7641       7602       7778
ENSG00000138459        830        852       1000        727        933
ENSG00000138463        332        262        342        272        441
ENSG00000138468        381        189        553        186        476
ENSG00000138472          0          0          0          0          0
ENSG00000138483          1          6          1          8          0
ENSG00000138495        124        128        173        114        171
ENSG00000138496       1304        775       1245        542       1015
ENSG00000138587         87         49        127         45        102
ENSG00000138592       1173       1186       1456        849       1548
ENSG00000138593       1873       1644       2261       1300       2751
ENSG00000138594       1337       1065       1457        800       1480
ENSG00000138600        742        669       1037        731        732
ENSG00000138604        861       1344       1083       1327       1479
ENSG00000138606        184        114        126         62         70
ENSG00000138613        592        499        872        576        928
ENSG00000138614        560        447        649        363        580
ENSG00000138615        285        905        691        963        470
ENSG00000138617        222        148        277        127        200
ENSG00000138621         77         71         89         46        111
ENSG00000138622          0          1          1          0          0
ENSG00000138623        175        149        364        214        325
ENSG00000138629        704        725        851        506        893
ENSG00000138639        491        354        340        201        558
ENSG00000138640        729        719        799        504       1056
ENSG00000138641        526        592        585        538        551
ENSG00000138642        228        147        278        134        202
ENSG00000138646        175         67         94         38         36
ENSG00000138650        328        278        338        106         31
ENSG00000138653          0          0          0          0          0
ENSG00000138658         94         43         96         21         93
ENSG00000138660        291        250        246        178        276
ENSG00000138663        688        561        782        482        768
ENSG00000138668       1626       1507       2012       1250       1888
ENSG00000138669        312        136        243         26        551
ENSG00000138670          0          3          1          0          3
ENSG00000138674      10046       7643      10771       5163      11610
ENSG00000138675       1470        962       1507        795       2633
ENSG00000138678         69        137        103        101         64
ENSG00000138684          0          0          0          0          0
ENSG00000138685       1313        934       1743        802       1727
ENSG00000138686        471        632        668        473        657
ENSG00000138688       4042       2820       4741       2439       5224
ENSG00000138696         23         54         39         45         42
ENSG00000138698        880        873       1355        812       1296
ENSG00000138709        203        224        230        175        273
ENSG00000138722          1          0          1          1          0
ENSG00000138735       8227       3062      14439       4044       8897
ENSG00000138738        280        245        393        161        292
ENSG00000138741          9          6          8          7         36
ENSG00000138744        114        121        241        239        163
ENSG00000138750        617        558        712        442        781
ENSG00000138755          1          2          0          0          0
ENSG00000138756        587        391       1090        251        955
ENSG00000138757       2867       2303       3175       1983       3670
ENSG00000138758      18635      19207      25826      12698      27589
ENSG00000138759          8         33         50         17          6
ENSG00000138760       8532       7328      11189       6762      11428
ENSG00000138764       1735       1227       1380        935       1649
ENSG00000138767        499        450        471        298        507
ENSG00000138768       2503       2168       2640       1937       2763
ENSG00000138769          9          4         10          3         11
ENSG00000138771        876        727        992        706        979
ENSG00000138772         28         32        161         80         56
ENSG00000138777        487        408        533        356        512
ENSG00000138778        166        151        259        103        208
ENSG00000138780        173        130        172        107        221
ENSG00000138785        163        173        212        112        200
ENSG00000138792          8         19          3          4         30
ENSG00000138794        183        132        171        103        199
ENSG00000138795        239        224        156        115         26
ENSG00000138796        621        518        587        420        587
ENSG00000138798          0          0          3          2          2
ENSG00000138801       1445       1134       1414        750       1240
ENSG00000138802       1073       1180       1149       1002       1328
ENSG00000138813          0          2          1          0          0
ENSG00000138814       1433       1316       1421        806       1613
ENSG00000138821        343        289        563        293        259
ENSG00000138823          1          3          3          2          1
ENSG00000138829       6648      16309       4467       7293      11865
ENSG00000138834       1549       1191       1740        695       1782
ENSG00000138835        930        722       1118        581       1024
ENSG00000138867       1728       1763       1967       1170       1998
ENSG00000138892          0          0          0          0          0
ENSG00000138942        988        966       1130        741       1050
ENSG00000138944        398        108        270         40        654
ENSG00000138964          1          0          0          0          0
ENSG00000139044          1          0          0          0          0
ENSG00000139053          0          0          0          0          0
ENSG00000139055          2          3          8         25         10
ENSG00000139083        462        485        682        358        635
ENSG00000139112       4147       5149       7978       5547       6812
ENSG00000139116         87         68         85         29        111
ENSG00000139117        201        165        242        121        208
ENSG00000139131        212        198        278        119        239
ENSG00000139132        380       1461        461       1303        496
ENSG00000139133         31         30         44         16         36
ENSG00000139144          0          0          0          0          0
ENSG00000139146        119        130        104         82        134
ENSG00000139151          0          0          0          0          0
ENSG00000139154        729        550        776        377        861
ENSG00000139155          0          0          1          0          3
ENSG00000139160         95         51        125         71         96
ENSG00000139163        628        658        567        528        629
ENSG00000139168        703        628        863        443        891
ENSG00000139173        217        106        259        106        228
ENSG00000139174        216        163        309        188        212
ENSG00000139178       1628       1559       2366       1714       1679
ENSG00000139180        124        105         93         63         77
ENSG00000139182        483        450        883        419        670
ENSG00000139187         23          3         14          5          8
ENSG00000139190        328        339        471        333        486
ENSG00000139192        305        215        272        122        359
ENSG00000139193          5          6         18          8         14
ENSG00000139194         84         78        144         58         97
ENSG00000139197        919        786        871        533        824
ENSG00000139200        282        399        568        422        654
ENSG00000139209        137         89        203        141        367
ENSG00000139211        178        225        190        114        178
ENSG00000139218       1708       1410       2034       1186       2322
ENSG00000139219          0          1          0          0          0
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ENSG00000139223          0          0          0          0          0
ENSG00000139233        209        199        196        148        208
ENSG00000139239       2058       2019       2651       1074       2802
ENSG00000139263       2236       1789       2325       1069       3134
ENSG00000139266        203        223        166        101        217
ENSG00000139269         27          7         36          7         33
ENSG00000139278       1230       1199       2173       1053       1895
ENSG00000139287          0          1          0          1          0
ENSG00000139289       2864       1247       2799        804       3067
ENSG00000139291        462        534        418        545        442
ENSG00000139292          0          9          2         13          0
ENSG00000139304         94         80        368        129        120
ENSG00000139318        145         72        191         84        170
ENSG00000139323        225        190        254        170        270
ENSG00000139324        959        701       1244        835       1435
ENSG00000139329      11239       4454      21296       7613      23489
ENSG00000139330          1          0          1          0          1
ENSG00000139343        283        211        283        153        259
ENSG00000139344         11         12         11          7         13
ENSG00000139350        436        363        499        301        530
ENSG00000139351          6          3         13          2          4
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ENSG00000139364         38         22        112         50         84
ENSG00000139370        526        466        522        383        625
ENSG00000139372        330        272        346        217        412
ENSG00000139405        181        146        179        105        207
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ENSG00000139428        138         78        172         64        118
ENSG00000139433        817        873       1231        697       1293
ENSG00000139436        736        816       1020        799        880
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ENSG00000139496        665        645        622        426        835
ENSG00000139505        843        731        844        567       1010
ENSG00000139508        223        156        292        174        269
ENSG00000139514        585        459        737        317        619
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ENSG00000139531        368        346        464        205        383
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ENSG00000139546        349        405        392        225        344
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ENSG00000139549          0          0          0          0          0
ENSG00000139567        770       1271        736        711        621
ENSG00000139572          0          0          0          0          0
ENSG00000139574          0          0          0          0          0
ENSG00000139579        393        380        405        237        413
ENSG00000139597        143        118        243        207        215
ENSG00000139610          0          0          6          1          3
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ENSG00000139620        342        277        396        244        438
ENSG00000139624        508        648        704        545        660
ENSG00000139625       1619       1281       1929        879       1760
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ENSG00000139629         89         56        265        133        286
ENSG00000139631        326        261        386        203        356
ENSG00000139636        580        598        673        452        648
ENSG00000139637        390        341        420        229        412
ENSG00000139641       3427       2755       3568       2138       3586
ENSG00000139644       9228      10197      12910       8896      11946
ENSG00000139645       1476       1440       1699        988       2094
ENSG00000139648          0          0          0          0          0
ENSG00000139651        890        773        856        557        876
ENSG00000139656          0          0          0          1          0
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ENSG00000139675       1495       1402       1276        928        923
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ENSG00000139684       1866       1761       2229       1379       2339
ENSG00000139687       1069       1193       1258        928       1250
ENSG00000139697       1258       1046       1421        780       1357
ENSG00000139714         15         19         59         19         37
ENSG00000139718        934        948       1074        675       1024
ENSG00000139719        207        173        236        154        239
ENSG00000139722        473        360        400        226        444
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ENSG00000139726       1098        948       1279        757       1432
ENSG00000139734        100        152        204        142        133
ENSG00000139737          5          2          0          0          1
ENSG00000139746        831        627       1021        483       1177
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ENSG00000139793       1376       1606       1500       1365       1561
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ENSG00000139800          0          0          0          0          0
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ENSG00000139832        100        118         82         53         94
ENSG00000139835         61         64         62         43         38
ENSG00000139842       1947       1955       2279       1450       2356
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ENSG00000139874        308        333        290         96        242
ENSG00000139880        189         96        220         81        313
ENSG00000139890          1          1          6          2          6
ENSG00000139899        295        245        238        119        208
ENSG00000139908         36         31         59         19         52
ENSG00000139910        298        210        365        148        511
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ENSG00000139921       1334       1294        981        870        994
ENSG00000139926       6314       4320       6749       4065       7928
ENSG00000139946        478        205        478        209        618
ENSG00000139970         12         10        203        115         68
ENSG00000139971        185         66        141         61         97
ENSG00000139973          3          2          7          3          3
ENSG00000139974        407        293        438        243        502
ENSG00000139977        559        479        636        455        650
ENSG00000139985         21          8         19         15         13
ENSG00000139988          1          0          2          0          5
ENSG00000139990       1248       1010       1581        753       1648
ENSG00000139998        220        151        331        177        425
ENSG00000140006         68         59         63         31         70
ENSG00000140009          2          1          5          3          6
ENSG00000140015          5          5         35          2          1
ENSG00000140022        570        258        489        167        156
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ENSG00000140092       7882       8446      10386       6709      10535
ENSG00000140093          3          0          1          1          3
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ENSG00000140105       3424       1369       4642       1136       2757
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ENSG00000140157        610        616        710        415        659
ENSG00000140181       3085       2818       2600       1104       3152
ENSG00000140199        683        446        939        469        817
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ENSG00000140264       3168       2687       2871       1780       2470
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ENSG00000140299       1510       1585       1823       1413       1884
ENSG00000140307        547        521        580        375        652
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ENSG00000140326        366        264        378        191        466
ENSG00000140332        538        379        550        238        525
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ENSG00000140382        729        683        905        584        966
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ENSG00000140463        628        504        885        597        814
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ENSG00000140471        114        107        156         63        144
ENSG00000140474        355        448        274        213        336
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ENSG00000140497       1195       1170       1438        994       1287
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ENSG00000140511         45        171        174        184         52
ENSG00000140519          0          2          0          1          1
ENSG00000140521        789        845        843        447        968
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ENSG00000140525        217        208        215        145        222
ENSG00000140526       1410       1290       1584       1246       1387
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ENSG00000140548        243        239        296        118        359
ENSG00000140553       1792       1667       1783       1036       1705
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ENSG00000140575       6535       6105       7574       4873       7969
ENSG00000140577       1206       1123       1346        781       1694
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ENSG00000140650        125        132        174        116        216
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ENSG00000143575        863        758       1056        542       1002
ENSG00000143578        122        103        142        111        133
ENSG00000143590         12         12         14          4         11
ENSG00000143595          0          0          1          0          0
ENSG00000143603          1          2          1          0          1
ENSG00000143612       2657       2525       2700       1924       2917
ENSG00000143614        644        559        658        471        784
ENSG00000143621       1615       1288       1864       1005       1919
ENSG00000143622        339        297        445        270        438
ENSG00000143624       2514       1895       2797       1382       2613
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ENSG00000143630        114         89         95         46         90
ENSG00000143631        659        344        370         74         79
ENSG00000143632          0          3          2          3          0
ENSG00000143633         93        114        147         95        136
ENSG00000143641       4051       4342       3901       2551       4814
ENSG00000143643        162        150        211        210        212
ENSG00000143653        898        748       1262        631       1069
ENSG00000143669       1092        863        855        576       1237
ENSG00000143674          6          4          2          1          2
ENSG00000143702       2408       1425       2754       1059       3016
ENSG00000143727        960        854       1099        737       1138
ENSG00000143740        611        367        681        275        700
ENSG00000143742       2581       2108       2549       1630       2843
ENSG00000143748        275        166        348        155        327
ENSG00000143751        253        213        280        151        307
ENSG00000143753       2060       2373       2420       1827       2859
ENSG00000143756        866        699       1016        645       1093
ENSG00000143761       5317       5811       6124       3868       5891
ENSG00000143768          1          1          0          0          1
ENSG00000143771        977       1104       1148        967        990
ENSG00000143772       1963       1025       1567        621       1505
ENSG00000143774       2187       2160       2471       1284       2271
ENSG00000143776       2088       2006       2666       1550       2853
ENSG00000143786        121         38        105         24        135
ENSG00000143793        169        149        149        102        128
ENSG00000143797        739        547        981        563       1053
ENSG00000143799       1764       1605       1826        926       1859
ENSG00000143801        176        171        292        178        347
ENSG00000143811        287        301        302        238        291
ENSG00000143815        664        694        414        307        644
ENSG00000143816        133        133        151         73        108
ENSG00000143819       2179       1966       2644       1635       3993
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ENSG00000143842        166        174        188        115        176
ENSG00000143845        152        145        172        152        137
ENSG00000143847        488        230        580        144        574
ENSG00000143850        474        193        921        205       1441
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ENSG00000143862        436        506        525        400        496
ENSG00000143867        852       1171       1326        461        588
ENSG00000143869         26         87         67        110         48
ENSG00000143870       3761       2656       3521       1887       3520
ENSG00000143878       1919       4415       2804       3281       2689
ENSG00000143882          7          8         11         10          8
ENSG00000143889        904        602        851        400        865
ENSG00000143891        761        308        777        220        789
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ENSG00000143933       4635       3989       6875       4051       6704
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ENSG00000143947       9909       9785       8329       5275       7343
ENSG00000143951        108         80        137         69        109
ENSG00000143952        569        513        622        418        886
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ENSG00000143971        398        428        526        340        523
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ENSG00000143995       2135       1736       2306        971       2291
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ENSG00000144021       1128        995       1510        786       1579
ENSG00000144026        241        164        219        121        343
ENSG00000144028       4813       3619       5383       2485       5872
ENSG00000144029        633        593        671        435        844
ENSG00000144031         59         58         54         37         80
ENSG00000144034        189        112        168         75        196
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ENSG00000144040        276        223        323        133        287
ENSG00000144043       2909       2761       3078       2100       2902
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ENSG00000144115        795        836        550        426        257
ENSG00000144118       1019       1044       1195        865       1111
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ENSG00000144152         41         42         62         33         35
ENSG00000144158         22         22         28         13          9
ENSG00000144161        109         50        136         71        160
ENSG00000144182         35         36         70         36         47
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ENSG00000144218         13          1          9          3         41
ENSG00000144224       3133       2596       3379       1973       3875
ENSG00000144227          0          0          0          0          0
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ENSG00000144231        202        185        234        146        238
ENSG00000144233        578        600        656        483        682
ENSG00000144278          7          4          2          3          0
ENSG00000144283       1061        877       1804        850       1687
ENSG00000144285         22         18         39         29         30
ENSG00000144290          0          0          0          0          0
ENSG00000144306        542        365        603        275        661
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ENSG00000144331          0          0          0          0          0
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ENSG00000144354         50         51         46          8         42
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ENSG00000144357       1010       1006       1252        949       1274
ENSG00000144362         35         39         44         63         39
ENSG00000144366       1161       1093       1260        652       1036
ENSG00000144369       1902        706       1891        506       2375
ENSG00000144381       2454       2143       2820       1464       2980
ENSG00000144395         28         46         18         21         38
ENSG00000144401        127        129        200         87        174
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ENSG00000144410          3          4         12          3          8
ENSG00000144426        549        441        631        321        606
ENSG00000144445        372        367        423        299        459
ENSG00000144451        257        167        257        155        280
ENSG00000144452         10          3         11          3          7
ENSG00000144455       1764       1438       2089       1246       1687
ENSG00000144460          0          0          0          0          0
ENSG00000144468        640        533        783        425        876
ENSG00000144476       1747       1202       1794        908       1174
ENSG00000144481          1          1          3          0          4
ENSG00000144485         16         33         30         22         16
ENSG00000144488        145         92         81         18          5
ENSG00000144504        130        112        175        101        163
ENSG00000144524        487        405        731        341        622
ENSG00000144535        247        216        234        149        264
ENSG00000144550          2          0          4          0          3
ENSG00000144554         47         37         41         32         42
ENSG00000144559        120        110        158         74        121
ENSG00000144560        531        568        601        293        749
ENSG00000144566        922        851       1146        801       1230
ENSG00000144567       2710       2263       2827       1656       2816
ENSG00000144579       2003       1806       2017       1137       1907
ENSG00000144580        588        516        625        334        634
ENSG00000144583        102        127        302        211        107
ENSG00000144589        326        293        370        204        301
ENSG00000144591        862        682        817        340        743
ENSG00000144596          7          0         11          3          5
ENSG00000144597        149        137        187        116        254
ENSG00000144619          1          0          1          1          1
ENSG00000144635        658        612        648        430        868
ENSG00000144642       1195       1269       1508       1163       1620
ENSG00000144644         28          1         31          5          3
ENSG00000144645        160        116        162         55        211
ENSG00000144647        764        783        688        396        522
ENSG00000144648          9         23          8         24          9
ENSG00000144649        167        310        104         83         10
ENSG00000144655        130        119         84         61         99
ENSG00000144659        480        474        496        370        539
ENSG00000144668         19          8         29          8         16
ENSG00000144671          0          1          1          0          0
ENSG00000144674       2729       2318       3069       1723       4612
ENSG00000144677        994        724        998        688       1070
ENSG00000144681        244        218        245        168        116
ENSG00000144711       1209        903       1723        717       1167
ENSG00000144712        227        166        365        182        236
ENSG00000144713      14336      13586      15756       7308      13810
ENSG00000144724       1780       3677       2327       2327       3113
ENSG00000144730       1122        655       1616        458        348
ENSG00000144736        345        263        499        224        504
ENSG00000144741        262        265        297        188        261
ENSG00000144744        921        982        980        758       1083
ENSG00000144746       4969       5557       5645       5056       5612
ENSG00000144747        964       1008       1062        749       1139
ENSG00000144749       1883       1678       1903        984       2394
ENSG00000144771          1          0          2          0          3
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ENSG00000144802        260        406        395        249        462
ENSG00000144810       2373       3263       3729       3563       3470
ENSG00000144815        893        712       1037        654       1060
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ENSG00000144824       2105       1431       2608       1083       2483
ENSG00000144827        404        225        441        185        442
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ENSG00000144840        386        315        469        275        417
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ENSG00000144848        681        589        763        434        862
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ENSG00000144857        929       1532       1508       1251        776
ENSG00000144867        538        549        709        429        755
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ENSG00000144891        107        215         59        113        103
ENSG00000144893         34         20         32         18         19
ENSG00000144895       1357       1027       1509        758       1583
ENSG00000144908          0          4          0          6          0
ENSG00000144909        343        281        380        208        429
ENSG00000144935        452        411        555        426        497
ENSG00000144959        153        202        361        243        306
ENSG00000144962          0          0          0          0          0
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ENSG00000145012       4057       4249       4743       3343       4634
ENSG00000145014        312        170        330        154        408
ENSG00000145016        343        424        379        309        429
ENSG00000145020        228        221        235        128        201
ENSG00000145022        493        560        569        433        473
ENSG00000145029        275        265        330        164        266
ENSG00000145040          8         19         10          5         11
ENSG00000145041        535        584        543        425        687
ENSG00000145050        756        747        763        456        718
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ENSG00000145147        746        824       1497        911       1303
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ENSG00000145220        128        117        159        102        170
ENSG00000145241        251        187        406        195        380
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ENSG00000145246        766        645       1049        631        945
ENSG00000145247        124         84        160         82        242
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ENSG00000145284        489        387        653        415        492
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ENSG00000145293        465        397        450        299        455
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ENSG00000145332        297        306        319        231        316
ENSG00000145335         81         70         25         12         22
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ENSG00000145349       3774       3974       3834       3157       4538
ENSG00000145354        234        251        282        186        284
ENSG00000145358         71         27         52         18         32
ENSG00000145362       2834       1198       2543        914       3149
ENSG00000145365        121         72        115         58        150
ENSG00000145375         82         80         77         60         93
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ENSG00000145388        510        445        632        371        635
ENSG00000145390       1907       7938       4218      13918       1701
ENSG00000145391       4079       3824       4821       2967       4963
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ENSG00000145431       1499        704       1066        417       1676
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ENSG00000145451          0          0          0          0          0
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ENSG00000145494        507        480        508        306        571
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ENSG00000145569          8         52         11         33          6
ENSG00000145592      14188      13963      14962       7042      14183
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ENSG00000145626          0          0          0          0          0
ENSG00000145632        597        240       1101        280        935
ENSG00000145642          1          0          0          0          0
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ENSG00000145681        101        170       2015       1366        584
ENSG00000145685       3596       1286       2980        747       3072
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ENSG00000145703        190         82         70         25         95
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ENSG00000145725       1076        898       1220        691       1329
ENSG00000145730       9454       7286      15352       9582      14207
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ENSG00000145736        567        521        524        305        663
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ENSG00000146574        816        878       1349        752       1280
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ENSG00000154165          0          0          0          0          0
ENSG00000154174       1405       1169       1726        924       1846
ENSG00000154175       8328       7185       7480       4240       5461
ENSG00000154188       1382       1858       2540       1784       4135
ENSG00000154198          0          0          0          0          0
ENSG00000154217        113        203        174        161        202
ENSG00000154222        698        754        758        498        652
ENSG00000154227          1          1          1          0          0
ENSG00000154229       2906       2846       4168       2304       4659
ENSG00000154237       1149       1084       1244        665       1121
ENSG00000154240        174        194        274        190        227
ENSG00000154252          0          1          0          0          3
ENSG00000154258       1117       1539       2227       1614       1844
ENSG00000154262       1514       2686       1781       2306       1782
ENSG00000154263        252        118        299         66        255
ENSG00000154265        332        330        607        392        417
ENSG00000154269          7          4          4          2          4
ENSG00000154274          2          1          1          1          3
ENSG00000154277       5921       4898       6105       3137       6248
ENSG00000154305       2195       1632       2397       1332       2773
ENSG00000154309        372        239        752        380        530
ENSG00000154310       1006        290       1195        334       1103
ENSG00000154316          1          0          1          0          0
ENSG00000154319         57         88         90         68         71
ENSG00000154328        191        169        217        128        244
ENSG00000154330       1929       1576       3332       1590       2258
ENSG00000154342          0          0          0          0          0
ENSG00000154358        512        293        148         37        488
ENSG00000154359        336        189        276        163        372
ENSG00000154370        285        294        262        130        295
ENSG00000154380       4112       5342       4703       3223       6156
ENSG00000154415          0          0          0          0          0
ENSG00000154429        132         77        186         79        176
ENSG00000154438          1          0          0          0          1
ENSG00000154447        518        522        729        364        491
ENSG00000154451          7          2          6          1          2
ENSG00000154473       1418       1258       1488        942       1509
ENSG00000154478          1          0          3          0          0
ENSG00000154479         16         30         20         14         27
ENSG00000154485          0          0          1          2          1
ENSG00000154493          2          1          6          0          1
ENSG00000154511       1662       1683       2186       1166       1993
ENSG00000154518       1423       1293       1544        950       1529
ENSG00000154529         87        122        137        156          6
ENSG00000154537          5         10          8          1          9
ENSG00000154545       1475        940       1159        445       1475
ENSG00000154548          8         11          6          3          1
ENSG00000154553        264        215        186         81         52
ENSG00000154556          2          4          7          2         85
ENSG00000154582        639        705        725        514        758
ENSG00000154589        148         66        199        105        166
ENSG00000154608        954        525       1106        365       1221
ENSG00000154611          0          0          0          0          0
ENSG00000154620          3          2          3          4          5
ENSG00000154639         17          4          5          6         16
ENSG00000154640        513        450        517        345        626
ENSG00000154642        243        170        221        158        223
ENSG00000154645          3          1          3          3          3
ENSG00000154646          0          0          0          0          0
ENSG00000154654       1544        698       2658        921       1360
ENSG00000154655         11          3          0          1          0
ENSG00000154678        653        625       1023        443       1526
ENSG00000154710         30         50         47         28         52
ENSG00000154719        196        182        239        159        260
ENSG00000154721        185        149        881        627        692
ENSG00000154723        617        596        787        466        730
ENSG00000154727        814        571        973        498       1100
ENSG00000154734       6297      36486      13641      36087      10482
ENSG00000154736        585       4871       2984       5544       1969
ENSG00000154743        127        177        151        126        171
ENSG00000154760        163        118        152         81        103
ENSG00000154764          0          0          0          0          0
ENSG00000154767       1873       1108       2233        797       2054
ENSG00000154768          0          0          0          0          0
ENSG00000154781        391        359        500        259        500
ENSG00000154783         23         25         46         11          4
ENSG00000154803       1235       1070        952        472       1224
ENSG00000154813        666        795        822        673        962
ENSG00000154814        100        103        116         94        108
ENSG00000154822        302        258        331        182        297
ENSG00000154832        819        732        825        398        864
ENSG00000154839         30         16         23          5         17
ENSG00000154845       1472       1444       1501       1015       1972
ENSG00000154856        850       4428        815       1142        961
ENSG00000154864        454         52        344         30        305
ENSG00000154874        269        206        396        148        478
ENSG00000154889        454        488        501        364        480
ENSG00000154898         54         43        110         39        185
ENSG00000154914          6         10          2          7          6
ENSG00000154917         42         32         68         28         61
ENSG00000154920         16         11         15          5         15
ENSG00000154928          8          3         16          7          9
ENSG00000154930        284        915        362        800        187
ENSG00000154945        872        883        921        727        954
ENSG00000154957        177        124        183        126        184
ENSG00000154975          0          0          0          0          0
ENSG00000154978       2041       1776       1801       1400       1771
ENSG00000154997          0          0          0          0          0
ENSG00000155008         94        102        120         90         90
ENSG00000155011         14          5         30          3         13
ENSG00000155016       1054        932       1467       1085       1324
ENSG00000155026          1          1          3          1          1
ENSG00000155034        224        222        269        178        287
ENSG00000155052          0          0          0          0          0
ENSG00000155066         14          8         11          6         17
ENSG00000155070          1          1          4          3          7
ENSG00000155085        188         89        237         82        188
ENSG00000155087          0          0          1          0          0
ENSG00000155090        772        706        876        268       1103
ENSG00000155093         27         20         11          7          9
ENSG00000155096       2413       1966       2454       1516       2615
ENSG00000155097       1565       1549       1428       1151       1941
ENSG00000155099        342        248        249        210        301
ENSG00000155100        195        197        205        141        196
ENSG00000155111        964        645        928        559        974
ENSG00000155115        373        354        503        292        539
ENSG00000155130       8421       3293       7960       2235      10541
ENSG00000155158        379        312        325        217        420
ENSG00000155189        234        219        246        169        227
ENSG00000155229       1201       1164       1428        743       1259
ENSG00000155249          0          0          0          0          0
ENSG00000155252        826        557        892        508        990
ENSG00000155254       2293       2195       2749       1762       2702
ENSG00000155256        475        395        512        291        462
ENSG00000155265          0          0          1          0          0
ENSG00000155269          0          0          0          0          0
ENSG00000155275        158        148        183         94        176
ENSG00000155282          0          0          1          0          1
ENSG00000155287        530        509        575        316        712
ENSG00000155304        744        590        822        462        890
ENSG00000155307          1          1          1          0          0
ENSG00000155313       1519       1244       1974       1148       1996
ENSG00000155324        220        316        437        695        391
ENSG00000155329        158        179        174        159        163
ENSG00000155330         95         79         91         60        137
ENSG00000155363        914        712        939        416       1182
ENSG00000155366       2184       2200       2061       1257       2415
ENSG00000155367          7          9         12          7          9
ENSG00000155368        704        788        854        510        928
ENSG00000155380        830        652        954        481        979
ENSG00000155393        209        268        167        157        160
ENSG00000155428         24         21         33         12         38
ENSG00000155438        319        280        319        202        347
ENSG00000155463       2002       1668       2269       1140       2543
ENSG00000155465        105        112        151        143        202
ENSG00000155495          0          0          0          0          1
ENSG00000155506       3773       4000       3767       2971       5325
ENSG00000155508        571        721        673        773        761
ENSG00000155511       2064       2510       3213       2644       1211
ENSG00000155530          2          5          4          4          4
ENSG00000155542         49         38         55         23         74
ENSG00000155545        421        397        474        270        452
ENSG00000155561        907        634       1140        516       1100
ENSG00000155592        200        162        224        114        268
ENSG00000155621        241        204        350        159        343
ENSG00000155622          0          0          0          1          0
ENSG00000155629         23         31         44         24        155
ENSG00000155636        216        171        250        157        271
ENSG00000155640        113         70        129         39        180
ENSG00000155657        331        263        375        161        235
ENSG00000155659          0          0          0          0          0
ENSG00000155660       5090       2787       5263       2095       4539
ENSG00000155666         56         45         62         16         72
ENSG00000155714          2          1          0          0          0
ENSG00000155719          0          0          1          0          0
ENSG00000155729        460        323        560        326        480
ENSG00000155744        315        258        321        215        353
ENSG00000155749         11         19         14         16         18
ENSG00000155754         28         27         15         12         27
ENSG00000155755        593        412        816        480       1174
ENSG00000155760       1613        880       2733        980       2196
ENSG00000155761          0          2          0          0          1
ENSG00000155792         27         12         58         18         63
ENSG00000155816        212        214        412        280        478
ENSG00000155827       1508        968       1668        799       1760
ENSG00000155833          0          0          0          0          0
ENSG00000155846         14          3          2          0          6
ENSG00000155849         15         40         19         31          1
ENSG00000155850        613        667        584        483        667
ENSG00000155858        130        135        113        100        139
ENSG00000155868        190        158        195        126        172
ENSG00000155875          2          2          2          2         12
ENSG00000155876       2012       1895       2262       1461       1943
ENSG00000155886          0          0          0          1          0
ENSG00000155890          0          0          0          0          0
ENSG00000155893        426        195        482        166        689
ENSG00000155897         49          0         12          2         34
ENSG00000155903        836        698        798        645       1210
ENSG00000155906        370        357        552        323        589
ENSG00000155918          4          1          5          1          5
ENSG00000155926          2          1         10          0          2
ENSG00000155957         99        102        193        167        176
ENSG00000155959        531        464        630        442        593
ENSG00000155961         14         10         19          4          3
ENSG00000155962        528        227        705        203        605
ENSG00000155966         12          7          2          0          0
ENSG00000155970        238        209        238        179        250
ENSG00000155974          3          3          3          2          6
ENSG00000155975        770        943       1008        832        926
ENSG00000155980         56         30         43         29         60
ENSG00000155984        459        440        521        414        487
ENSG00000156006          0          0          0          0          0
ENSG00000156009          1          0          1          0          0
ENSG00000156011       2334       1647       2491        853       3643
ENSG00000156017        476        274        373        220        429
ENSG00000156026        655        718       1151        654        999
ENSG00000156030        981        819        951        459        826
ENSG00000156042        132         91        127         86         99
ENSG00000156049         88         56        172         69         59
ENSG00000156050        199         94        210         72        227
ENSG00000156052       1339       1395       1815       1197       2058
ENSG00000156076          0          0          2          0          0
ENSG00000156096          0          0          0          0          0
ENSG00000156097          3          3          5          1          3
ENSG00000156103         78         38         32         13         27
ENSG00000156110        395        339        517        310        500
ENSG00000156113       1269        502       1022        472        883
ENSG00000156127          0          0          0          0          3
ENSG00000156136        187        133        158         97        200
ENSG00000156140        112        178        385        221        129
ENSG00000156150          0          0          0          0          0
ENSG00000156162        950       1034       1079        900        906
ENSG00000156170        142        102        193        104        141
ENSG00000156171       1174        926       1506        984       1554
ENSG00000156172         42         50        108         48         41
ENSG00000156194          0          0          0          0          2
ENSG00000156206          1          0          0          1          0
ENSG00000156218          6          4          6          9          7
ENSG00000156219          3          3          0          1          3
ENSG00000156222          0          0          0          0          0
ENSG00000156232        241        308        275        224        317
ENSG00000156234          0          0          0          0          0
ENSG00000156239        292        150        351        109        392
ENSG00000156253        411        327        498        326        413
ENSG00000156256        915        881       1118        757       1231
ENSG00000156261       2397       2295       2419       1823       2415
ENSG00000156265        391        169        613        300        593
ENSG00000156269          0          0          0          1          0
ENSG00000156273       1386        962       1544        979       1702
ENSG00000156282          0          0          0          0          0
ENSG00000156284          0          0          0          0          0
ENSG00000156298          3          1          0          1          1
ENSG00000156299          0          4          4          1          3
ENSG00000156304        807        776       1349        645       1051
ENSG00000156313         73        108        121         83        166
ENSG00000156345        204        143        197         66        225
ENSG00000156374        186        207        179        146        184
ENSG00000156381         67         65         98         41         86
ENSG00000156384         92         74         93         67         69
ENSG00000156395          0          0          0          0          0
ENSG00000156398         41         31         52         46         27
ENSG00000156411        741        700        815        376        861
ENSG00000156413          0          0          0          0          0
ENSG00000156414         11         10          3          2          0
ENSG00000156427         33         33         72         51          9
ENSG00000156453         19          6          8          2         46
ENSG00000156463          7          9          8          6         16
ENSG00000156466         14          4         16          4         10
ENSG00000156467       2420       2041       2637       1411       3208
ENSG00000156469        228        209        271        152        273
ENSG00000156471       1988       1558       3328       1234       3515
ENSG00000156475          0          0          6          0          1
ENSG00000156482       3802       3722       3904       1830       3428
ENSG00000156486        179        174        258        130        204
ENSG00000156500         50         57         94         40         77
ENSG00000156502        320        267        377        200        406
ENSG00000156504        355        416        463        341        373
ENSG00000156508     297906     255662     329988     165709     290288
ENSG00000156509          2          3          5          1          1
ENSG00000156510          2          1          2          1          0
ENSG00000156515       2410       2192       2577       1435       2678
ENSG00000156521        300        341        231        204        266
ENSG00000156531        639        530        682        420        656
ENSG00000156535       3887       3341       3130       2149       5133
ENSG00000156564          0          0          0          0          0
ENSG00000156574          1          1          2          0          1
ENSG00000156575          0          0          0          0          0
ENSG00000156587       1395       1426       1588        985       1566
ENSG00000156599       2119       2133       2617       1834       2941
ENSG00000156603        221        179        263        155        272
ENSG00000156639       1870       1510       2454       1417       2556
ENSG00000156642       2177       2188       3158       2225       2536
ENSG00000156650       1785       1651       2030       1065       2332
ENSG00000156671       1260       1516       1522       1476       1403
ENSG00000156675        460       1115       1312       1840       1301
ENSG00000156687          0          0          0          0          0
ENSG00000156689         28         25         55         72         30
ENSG00000156697        349        335        377        225        532
ENSG00000156709        440        427        482        262        541
ENSG00000156711         69         87        114         91        278
ENSG00000156735        473        403        588        460        627
ENSG00000156738          0          0          0          0          0
ENSG00000156750          0          0          2          1          0
ENSG00000156755          0          0          0          0          0
ENSG00000156787        127        128        152         81        165
ENSG00000156795         87         82         95         63        120
ENSG00000156802        459        372        586        256        495
ENSG00000156804       2239       5642       2283       4115       2384
ENSG00000156831        277        259        294        205        320
ENSG00000156853        185        173        243        124        233
ENSG00000156858        489        513        445        300        477
ENSG00000156860       1019       1091       1219        770       1137
ENSG00000156869        226        116        218         68        259
ENSG00000156873        229        203        257        158        222
ENSG00000156875       1027        983       1157        803       1126
ENSG00000156876         59         35         65         27         80
ENSG00000156885          0          0          0          0          0
ENSG00000156886          0          0          0          0          0
ENSG00000156920          0          0          0          0          1
ENSG00000156925          0          0          0          0          0
ENSG00000156928        243        276        278        210        318
ENSG00000156931        929        611       1127        485       1237
ENSG00000156958        196        173        203        166        225
ENSG00000156959          1          2          0          0          0
ENSG00000156966          3          6          5          5          8
ENSG00000156968          3          1          5          3          5
ENSG00000156970         29         27         21         17         11
ENSG00000156973        317        249        332        159        390
ENSG00000156976       6203       5236       7594       3720       7533
ENSG00000156983        458        353        410        228        464
ENSG00000156990        295        272        339        196        304
ENSG00000157005          5          2         22          0          4
ENSG00000157014        312        317        257        217        279
ENSG00000157017          1          2          2          2          5
ENSG00000157020       1653       1415       1950        823       2028
ENSG00000157021         63         68         60         37        107
ENSG00000157036        220        232        270        275        274
ENSG00000157045        896        772       1070        782       1325
ENSG00000157060          0          1          0          0          0
ENSG00000157064          1          3          5          6         34
ENSG00000157077        692        589       1004        504        961
ENSG00000157087          0          2          0          1          0
ENSG00000157093          0          0          0          0          0
ENSG00000157103          0          0          0          0          0
ENSG00000157106       3192       2636       3245       1897       3503
ENSG00000157107        753        773        844        697        865
ENSG00000157110       1906       3545       2400       2616       2623
ENSG00000157111         21         24         54         29         28
ENSG00000157119          0          0          0          0          0
ENSG00000157131          0          0          0          0          0
ENSG00000157150         31        262         35        148         70
ENSG00000157152          8        127          9         30         12
ENSG00000157168         83         25         51         12        218
ENSG00000157181        411        392        547        309        613
ENSG00000157184        144        100        224         96        205
ENSG00000157191       1150        947       1514       1014       1431
ENSG00000157193         48         52         63         29         71
ENSG00000157211          0          1          0          0          0
ENSG00000157212        241        209        271        117        276
ENSG00000157214       1307       4089       1645       4100       1016
ENSG00000157216       1268       1811       1379       1609       1274
ENSG00000157219          0          0          0          0          0
ENSG00000157224        538        581        726        582        665
ENSG00000157227      28891      25980      32661      17710      41224
ENSG00000157240       2013       1857       1921       1227       1742
ENSG00000157259        978        890       1131        622       1333
ENSG00000157303          2          1         11          0          0
ENSG00000157306         17         12         23         11         13
ENSG00000157315          6          7          7          1         14
ENSG00000157322          7          6          5          2          5
ENSG00000157326        358        389        397        212        452
ENSG00000157330          1          0          1          0          0
ENSG00000157335          5          7          3          1          4
ENSG00000157343         14         16         20         10          9
ENSG00000157349        389        358        458        342        603
ENSG00000157350        404        347        520        186        495
ENSG00000157353        244        219        214        139        234
ENSG00000157358          1          1          0          0          0
ENSG00000157368         76          6        106         22        104
ENSG00000157379        432        269        326        142        436
ENSG00000157388          5          6          8          3          6
ENSG00000157399         73         60         44         26        173
ENSG00000157404        518        329        835        223        543
ENSG00000157423        133        119        182         84        190
ENSG00000157426        277        210        344        176        305
ENSG00000157429         54         34         75         25         55
ENSG00000157445        205         95        165         51        105
ENSG00000157450        841        727        969        568        985
ENSG00000157456         27         28         40         29         42
ENSG00000157470          4          5          8          5          0
ENSG00000157483       1063       1943       2260       1987       1590
ENSG00000157500       1142        996       1137        794       1176
ENSG00000157502          2         21          3         11          0
ENSG00000157510        209        709        291        530        361
ENSG00000157514        377       4348        522       3098        357
ENSG00000157538       1571       1784       1675       1295       1715
ENSG00000157540        987        917       1015        646       1088
ENSG00000157542          2          1          3          8          6
ENSG00000157551          1          2          4          1          3
ENSG00000157554          2          4          7          4          2
ENSG00000157557       1211        898       1089        726       1502
ENSG00000157570         69         60         62         23         27
ENSG00000157578         21         10         33         10         26
ENSG00000157593       1778       1702       1880       1110       2020
ENSG00000157600        310        196        251        147        356
ENSG00000157601        303         71        238         88        297
ENSG00000157613       3613       1937       4186       1241       4365
ENSG00000157617        528        755        521        861        775
ENSG00000157625        575        415        627        321        702
ENSG00000157637       2688       2549       2885       1934       2228
ENSG00000157653         16          9          9         10         19
ENSG00000157654          0          0          0          0          0
ENSG00000157657        787        409        848        271        992
ENSG00000157680        425        257        425        701        984
ENSG00000157693        232        179        332        131        329
ENSG00000157703          1          0          0          0          0
ENSG00000157734         18         16         11          8         19
ENSG00000157741        604        495        740        398        729
ENSG00000157764        541        465        700        393        665
ENSG00000157765          0          2          0          0          0
ENSG00000157766          6          4        393        212        156
ENSG00000157778        137        150        156         94        143
ENSG00000157782         15          2          5          2          7
ENSG00000157796       1423       1535       1703       1319       1657
ENSG00000157800        943        881       1110        663        890
ENSG00000157823        490        495        513        347        579
ENSG00000157827       1231       1594       1450       1245       1612
ENSG00000157828          1          0          0          0          1
ENSG00000157833        158        130        245        134        192
ENSG00000157837       1059        852       1205        776       1106
ENSG00000157851          0          0          0          0          0
ENSG00000157856          1          0          0          0          1
ENSG00000157869        328        281        323        186        319
ENSG00000157870        325        357        342        206        335
ENSG00000157873        637        461        482        189        478
ENSG00000157881        327        332        280        150        329
ENSG00000157884          0          0          0          0          0
ENSG00000157890          3          5          3          2          5
ENSG00000157895        319        252        372        151        314
ENSG00000157911        203        132        262        110        284
ENSG00000157916       2053       2129       2399       1605       2371
ENSG00000157927         30         53         56         30         40
ENSG00000157933       2174       1785       2263       1273       2441
ENSG00000157950          0          0          0          0          0
ENSG00000157954       1675       1831       2319       1608       2265
ENSG00000157965          0          0          0          0          0
ENSG00000157978        437        441        748        415        575
ENSG00000157985       1172        971       1212        580       1281
ENSG00000157992         11          6         11          4          9
ENSG00000157999         10          7         13          4         21
ENSG00000158006        212        178        307        138        293
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ENSG00000158156        158        184        178        107        175
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ENSG00000164930        630        942       1012       1377       1502
ENSG00000164932        800        974       1101       1534       3485
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ENSG00000164970        440        378        460        240        472
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ENSG00000164978        304        296        314        171        293
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ENSG00000164985       1642       1065       2113        959       2012
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ENSG00000165029       5601       5304       8659       5618      11019
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ENSG00000168405        131         95        119        127        109
                SRR1039517 SRR1039520 SRR1039521
ENSG00000000003       1047        770        572
ENSG00000000005          0          0          0
ENSG00000000419        799        417        508
ENSG00000000457        331        233        229
ENSG00000000460         63         76         60
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ENSG00000000971      11027       5176       7995
ENSG00000001036       1439       1359       1109
ENSG00000001084        714        696        704
ENSG00000001167        584        360        269
ENSG00000001460        210        155        177
ENSG00000001461       2751       2467       2905
ENSG00000001497        806        493        475
ENSG00000001561         38        134        172
ENSG00000001617        697        618        599
ENSG00000001626          6          5          5
ENSG00000001629       2514       1888       1660
ENSG00000001630         87         31         59
ENSG00000001631       1163        731        744
ENSG00000002016        257        160        137
ENSG00000002079          0          0          1
ENSG00000002330        260        156        177
ENSG00000002549       1824        853       1031
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ENSG00000002834      11970       5766       7825
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ENSG00000002933         27         70        109
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ENSG00000003096        284        485        224
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ENSG00000003393       1509        768        864
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ENSG00000003402       5198       1262       3761
ENSG00000003436       4981       3452       3342
ENSG00000003509        396        251        248
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ENSG00000003987         51         12         27
ENSG00000003989        102         18         46
ENSG00000004059       1986       1028       1347
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ENSG00000004142       2301       1133       1256
ENSG00000004399       5992       2718       2809
ENSG00000004455       2274       1017        921
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ENSG00000004534       1714       1171       1013
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ENSG00000005020        827        769        904
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ENSG00000005059        204        211        236
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ENSG00000005486       1423        763        687
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ENSG00000005810       3682       2216       2298
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ENSG00000005889       1115        929       1028
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ENSG00000006015        366        410        375
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ENSG00000006062        177        199        116
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ENSG00000006114       1211        990        742
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ENSG00000006125       9420       5580       6653
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ENSG00000006327       1360        582        367
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ENSG00000006453        219        158        129
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ENSG00000006534       2571        525        843
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ENSG00000006638         49         67         52
ENSG00000006652       1768       1178       1097
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ENSG00000006704        276        299        331
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ENSG00000006715       3223       2174       2138
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ENSG00000006744       1344        693        924
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ENSG00000006831       1615        878       1102
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ENSG00000007255        175        114        101
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ENSG00000007350          0          0          0
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ENSG00000007376        404        218        253
ENSG00000007384       2524       1714       1983
ENSG00000007392        826        626        613
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ENSG00000007520        728        396        436
ENSG00000007541       1005        557        730
ENSG00000007545        303        197        191
ENSG00000007866       2207       1123       1765
ENSG00000007908          0          0          0
ENSG00000007923       1009        540        549
ENSG00000007933        346        280        284
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ENSG00000007952         17          4          9
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ENSG00000008083        541        227        364
ENSG00000008086        176        106         93
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ENSG00000008130       2354       1103       2475
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ENSG00000008256       8634       2115       5313
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ENSG00000008282       2700       1835       2144
ENSG00000008283        837        440        427
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ENSG00000008311       1037        447       1103
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ENSG00000008394       8116       2520       2678
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ENSG00000009335       3246       1742       2027
ENSG00000009413      10312       4700      11982
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ENSG00000010438         35         26         19
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ENSG00000011260        561        325        389
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ENSG00000011304       5568       3118       3948
ENSG00000011332         24          5          7
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ENSG00000011376        611        346        333
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ENSG00000011422        561        406        397
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ENSG00000011451       2141       1405       1415
ENSG00000011454       3745       1846       2501
ENSG00000011465     313112     378834     372489
ENSG00000011478        252        110        163
ENSG00000011485       1666        672       1110
ENSG00000011523       1240        658        949
ENSG00000011566       3045        856       1722
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ENSG00000011638        988        921       1011
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ENSG00000012061       1454        657        713
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ENSG00000012223          4          0          0
ENSG00000012232       1982       1109       1281
ENSG00000012504          0          0          1
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ENSG00000013016       3358       1197       1535
ENSG00000013275       1429        739        778
ENSG00000013288       5100       2208       2814
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ENSG00000013297       1173       5335       1735
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ENSG00000013441       3406       2235       2991
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ENSG00000013563        289        143        137
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ENSG00000040341        859        524        593
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ENSG00000167123       5572       4360       4483
ENSG00000167130        157        123        118
ENSG00000167131          0          0          0
ENSG00000167136         39         38         34
ENSG00000167139          0          0          0
ENSG00000167157        718        565        483
ENSG00000167165          0          0          0
ENSG00000167173        424        244        263
ENSG00000167178          1          2          2
ENSG00000167182        515        325        325
ENSG00000167183          0          3          1
ENSG00000167186        361        252        223
ENSG00000167191       2595       1387       6433
ENSG00000167193       3281       1904       2373
ENSG00000167194          0          0          0
ENSG00000167195          0          3          1
ENSG00000167196        748        519        350
ENSG00000167202       8754       6507       6799
ENSG00000167207          0          0          2
ENSG00000167208          0          0          0
ENSG00000167210          0          0          0
ENSG00000167216        167        231        180
ENSG00000167220        335        202        190
ENSG00000167230          1          1          0
ENSG00000167232        617        342        318
ENSG00000167236          0          0          0
ENSG00000167244      15336       1980       2786
ENSG00000167257        513        314        296
ENSG00000167258       1918       1098       1144
ENSG00000167261          2          0          0
ENSG00000167264        149         96         95
ENSG00000167272        322        177        169
ENSG00000167280        453        333        305
ENSG00000167281          2          2          1
ENSG00000167283       1221        625        750
ENSG00000167286          0          0          0
ENSG00000167291       4737       2028       3198
ENSG00000167302        213        135        152
ENSG00000167306         19         20          8
ENSG00000167311         39         34         11
ENSG00000167315       1141        859        923
ENSG00000167323       2288       1134       1638
ENSG00000167325        884        718        733
ENSG00000167332          4          0          1
ENSG00000167333        467        316        320
ENSG00000167346          0          0          0
ENSG00000167355          0          0          0
ENSG00000167359          0          0          0
ENSG00000167360          0          0          0
ENSG00000167363        101        117         78
ENSG00000167371        152        447        301
ENSG00000167377         57         39         35
ENSG00000167378        500        434        432
ENSG00000167380        416        311        249
ENSG00000167383        424        265        231
ENSG00000167384        136        137         95
ENSG00000167390          3          0          0
ENSG00000167393        237        203        154
ENSG00000167394        310        148        226
ENSG00000167395        802        474        556
ENSG00000167397        294        187        218
ENSG00000167414          1          0          0
ENSG00000167419          1          2          0
ENSG00000167434          0          0          0
ENSG00000167447        554        318        363
ENSG00000167459          0          0          0
ENSG00000167460     103111      34815      50480
ENSG00000167461        448        229        278
ENSG00000167468       7526       5420       4514
ENSG00000167470       1396        900        793
ENSG00000167476          0          2          0
ENSG00000167483         17         12          7
ENSG00000167487        147        124        119
ENSG00000167491       1387       1038        981
ENSG00000167494          0          0          0
ENSG00000167508        522        252        284
ENSG00000167513         18         32         19
ENSG00000167515        790        600        561
ENSG00000167522       7427       3700       3966
ENSG00000167523         89         64         67
ENSG00000167524         10          3          6
ENSG00000167525         42         30         42
ENSG00000167526      22882      16829      17206
ENSG00000167528        364        219        234
ENSG00000167531          0          0          0
ENSG00000167535       1704       1131       1262
ENSG00000167536         40         20         21
ENSG00000167543        711        445        705
ENSG00000167548       3812       1671       2069
ENSG00000167549       2124        589       3829
ENSG00000167550         36         12         23
ENSG00000167552       9584       8952       3668
ENSG00000167553       3654       2675       1330
ENSG00000167554        123         89         71
ENSG00000167555       1042        635        475
ENSG00000167562        172        121        110
ENSG00000167565        374        216        229
ENSG00000167566       1040        660        633
ENSG00000167578         94         55         68
ENSG00000167580          0          0          0
ENSG00000167588          7          6          3
ENSG00000167595        203        182        151
ENSG00000167600         41         74         69
ENSG00000167601       6080       3984       4782
ENSG00000167604         47         30         43
ENSG00000167608         30         13         16
ENSG00000167612          8          2          0
ENSG00000167613          0          0          0
ENSG00000167614          7          5          3
ENSG00000167615       5524       3124       3306
ENSG00000167617        408        306        309
ENSG00000167618          0          0          0
ENSG00000167619          1          0          0
ENSG00000167625        424        182        231
ENSG00000167632        647        401        501
ENSG00000167633          0          0          0
ENSG00000167634          1          0          0
ENSG00000167635       1636       1010        853
ENSG00000167637        120         75         59
ENSG00000167641        844         30        232
ENSG00000167642        186         31        109
ENSG00000167644          0          0          0
ENSG00000167645       1526        310        702
ENSG00000167646          4          6          1
ENSG00000167653         35          3          2
ENSG00000167654          0          0          0
ENSG00000167656          0          0          0
ENSG00000167657       2021       1098       1422
ENSG00000167658      71428      54351      59279
ENSG00000167664          0          0          0
ENSG00000167670        181        104        118
ENSG00000167671       3530       2085       2493
ENSG00000167674       1815       1134       1191
ENSG00000167676         95        111         62
ENSG00000167680         25         38          8
ENSG00000167685        556        391        336
ENSG00000167693       3193       1158        958
ENSG00000167695        908        498        400
ENSG00000167699        744        649        573
ENSG00000167700        224        117        118
ENSG00000167701         44         18         19
ENSG00000167702        376        155        262
ENSG00000167703        353        159        153
ENSG00000167705        293        109        155
ENSG00000167711          7          7         19
ENSG00000167716       1081        857        941
ENSG00000167720        167        111        120
ENSG00000167721       1655        705        722
ENSG00000167723         46         30         31
ENSG00000167733        186        112        119
ENSG00000167740        736        558        570
ENSG00000167741          0          0          0
ENSG00000167747        258        248        195
ENSG00000167748          0          0          0
ENSG00000167749          0          0          0
ENSG00000167751          0          0          0
ENSG00000167754          0          0          0
ENSG00000167755          0          0          0
ENSG00000167757          0          0          0
ENSG00000167759          0          1          0
ENSG00000167765         13          4          9
ENSG00000167766       1072        848        670
ENSG00000167767         47          6          3
ENSG00000167768          0          0          0
ENSG00000167769          1          0          1
ENSG00000167770       1378        774        882
ENSG00000167771         40         67         22
ENSG00000167772       1428       1435       1635
ENSG00000167774          0          0          0
ENSG00000167775        370        263        226
ENSG00000167778       1223        612        646
ENSG00000167779       2840       4695       6487
ENSG00000167780          0          2          8
ENSG00000167785        492        330        360
ENSG00000167791          0          0          0
ENSG00000167792       1862       1128       1268
ENSG00000167797        609        174        371
ENSG00000167798          0          0          0
ENSG00000167799         21         21         26
ENSG00000167800          0          1          0
ENSG00000167807          0          0          0
ENSG00000167815       1135        767        652
ENSG00000167822          0          0          0
ENSG00000167825          0          0          0
ENSG00000167840         96         63         69
ENSG00000167842        318        233        205
ENSG00000167850          0          0          0
ENSG00000167851          0          0          0
ENSG00000167858          0          0          0
ENSG00000167861         11          6          9
ENSG00000167862        352        142        193
ENSG00000167863       1547        735        836
ENSG00000167874          9          7          1
ENSG00000167880          1          1          0
ENSG00000167881       1983       1172       1044
ENSG00000167889          3          6          3
ENSG00000167895          0          0          0
ENSG00000167900         86         71         52
ENSG00000167904        245        234        186
ENSG00000167910          0          1          1
ENSG00000167912         71         70         34
ENSG00000167914          0          0          0
ENSG00000167916          0          0          0
ENSG00000167920        162        164        178
ENSG00000167925        447        250        412
ENSG00000167930       1204        819       1020
ENSG00000167941          2          0          0
ENSG00000167945          0          3          6
ENSG00000167962       1073        509        642
ENSG00000167964         12         16         14
ENSG00000167965        810        513        434
ENSG00000167967        555        310        379
ENSG00000167968          5          3          6
ENSG00000167969        595        370        472
ENSG00000167970          0          0          0
ENSG00000167971          3          4          4
ENSG00000167972         76        149        207
ENSG00000167977        469        258        336
ENSG00000167978      17555       9584      10187
ENSG00000167981         55         29         22
ENSG00000167984         30         19         17
ENSG00000167985        139         62         90
ENSG00000167986      11419       7333       8370
ENSG00000167987        473        302        308
ENSG00000167992        155        355        106
ENSG00000167994       1050        759        929
ENSG00000167995        379        459        282
ENSG00000167996      17978      12218       9384
ENSG00000168000         35         31         39
ENSG00000168002        810        578        589
ENSG00000168003       1476       1475       1511
ENSG00000168004          1         12         30
ENSG00000168005        583        329        352
ENSG00000168010        321        235        165
ENSG00000168014        892        371        381
ENSG00000168016       2395       1726       1892
ENSG00000168026         97         92        113
ENSG00000168028      18426      13379      12653
ENSG00000168032         84         82         96
ENSG00000168036       7431       4685       4864
ENSG00000168038         85         60         49
ENSG00000168040         93         81         74
ENSG00000168056       7148       5474       6125
ENSG00000168060        199        171        159
ENSG00000168061         73         85         69
ENSG00000168062         41         34          9
ENSG00000168065          0          0          1
ENSG00000168066       4417       2428       2486
ENSG00000168067        265        185        185
ENSG00000168070          0          0          1
ENSG00000168071         41         37         23
ENSG00000168077       2373       2124       1664
ENSG00000168078         16         26         23
ENSG00000168079         69        292        967
ENSG00000168081          0          0          0
ENSG00000168090       1872       1192       1052
ENSG00000168092       2478       1151       1703
ENSG00000168096        411        270        259
ENSG00000168101        356        167        242
ENSG00000168116        246        171        180
ENSG00000168118        696        542        637
ENSG00000168122          1          1          1
ENSG00000168124          2          0          0
ENSG00000168126          1          0          0
ENSG00000168129          0          0          0
ENSG00000168131          0          0          0
ENSG00000168135          0          0          1
ENSG00000168137       3205       2138       1709
ENSG00000168140       3704       4427       4363
ENSG00000168143          0          0          0
ENSG00000168148          2          0          3
ENSG00000168152         78         68         64
ENSG00000168158          2          5          0
ENSG00000168159       2417       1688       1406
ENSG00000168172       2122       1227       1493
ENSG00000168175       2146        971       1159
ENSG00000168209        669        459        725
ENSG00000168214       5652       7027       4171
ENSG00000168216       1433        870        918
ENSG00000168228        252        169        159
ENSG00000168229          1          0          1
ENSG00000168234       1017        395        698
ENSG00000168237         41         21         30
ENSG00000168242          0          0          0
ENSG00000168243          0          0          0
ENSG00000168246        891        713        668
ENSG00000168255        326        359        332
ENSG00000168256        761        496        608
ENSG00000168259       1212        802        828
ENSG00000168260          1          0          0
ENSG00000168263          1          0          1
ENSG00000168264       1106       1162        837
ENSG00000168267          0          0          0
ENSG00000168268       1632        908        976
ENSG00000168269          1          0          0
ENSG00000168273         88         60         49
ENSG00000168274          4          0          0
ENSG00000168275        167         73        106
ENSG00000168280          5          6          4
ENSG00000168282         16         14         14
ENSG00000168283        832        623        603
ENSG00000168286        412        266        327
ENSG00000168288       2022       1108       1240
ENSG00000168291       1116        516        640
ENSG00000168297       2195       1571       1435
ENSG00000168298          1          2          0
ENSG00000168300       1607       1394       1287
ENSG00000168301        172        119        125
ENSG00000168303        538        191        395
ENSG00000168306        516        409        334
ENSG00000168309         65          4        193
ENSG00000168310        939        522        790
ENSG00000168314          0          0          0
ENSG00000168329          0          1          0
ENSG00000168333          0          0          0
ENSG00000168334          0          3          0
ENSG00000168348          0          0          0
ENSG00000168350          2          8          5
ENSG00000168356          4          2          8
ENSG00000168367          0          0          0
ENSG00000168374       8952       4577       4902
ENSG00000168379          0          0          0
ENSG00000168384          0          0          0
ENSG00000168385      18998      12038      11405
ENSG00000168386       2533       1663       1242
ENSG00000168389         43          5          5
ENSG00000168393        291        209        197
ENSG00000168394        661        488        494
ENSG00000168395        379        279        328
ENSG00000168397       1236        755        811
ENSG00000168398       4530       6928       1219
ENSG00000168404        106         67         79
ENSG00000168405        180        110        218
 [ reached getOption("max.print") -- omitted 51178 rows ]

SummarizedExperiment:“行”数据(基因信息)

# 访问SummarizedExperiment信息,返回一个数据框
rowData(airway)
DataFrame with 63677 rows and 10 columns
                        gene_id     gene_name  entrezid   gene_biotype
                    <character>   <character> <integer>    <character>
ENSG00000000003 ENSG00000000003        TSPAN6        NA protein_coding
ENSG00000000005 ENSG00000000005          TNMD        NA protein_coding
ENSG00000000419 ENSG00000000419          DPM1        NA protein_coding
ENSG00000000457 ENSG00000000457         SCYL3        NA protein_coding
ENSG00000000460 ENSG00000000460      C1orf112        NA protein_coding
...                         ...           ...       ...            ...
ENSG00000273489 ENSG00000273489 RP11-180C16.1        NA      antisense
ENSG00000273490 ENSG00000273490        TSEN34        NA protein_coding
ENSG00000273491 ENSG00000273491  RP11-138A9.2        NA        lincRNA
ENSG00000273492 ENSG00000273492    AP000230.1        NA        lincRNA
ENSG00000273493 ENSG00000273493  RP11-80H18.4        NA        lincRNA
                gene_seq_start gene_seq_end              seq_name seq_strand
                     <integer>    <integer>           <character>  <integer>
ENSG00000000003       99883667     99894988                     X         -1
ENSG00000000005       99839799     99854882                     X          1
ENSG00000000419       49551404     49575092                    20         -1
ENSG00000000457      169818772    169863408                     1         -1
ENSG00000000460      169631245    169823221                     1          1
...                        ...          ...                   ...        ...
ENSG00000273489      131178723    131182453                     7         -1
ENSG00000273490       54693789     54697585 HSCHR19LRC_LRC_J_CTG1          1
ENSG00000273491      130600118    130603315          HG1308_PATCH          1
ENSG00000273492       27543189     27589700                    21          1
ENSG00000273493       58315692     58315845                     3          1
                seq_coord_system        symbol
                       <integer>   <character>
ENSG00000000003               NA        TSPAN6
ENSG00000000005               NA          TNMD
ENSG00000000419               NA          DPM1
ENSG00000000457               NA         SCYL3
ENSG00000000460               NA      C1orf112
...                          ...           ...
ENSG00000273489               NA RP11-180C16.1
ENSG00000273490               NA        TSEN34
ENSG00000273491               NA  RP11-138A9.2
ENSG00000273492               NA    AP000230.1
ENSG00000273493               NA  RP11-80H18.4
# 访问RangedSummarizedExperiment信息,返回一个GRangesList对象
rowRanges(airway)
GRangesList object of length 63677:
$ENSG00000000003
GRanges object with 17 ranges and 2 metadata columns:
       seqnames            ranges strand |   exon_id       exon_name
          <Rle>         <IRanges>  <Rle> | <integer>     <character>
   [1]        X 99883667-99884983      - |    667145 ENSE00001459322
   [2]        X 99885756-99885863      - |    667146 ENSE00000868868
   [3]        X 99887482-99887565      - |    667147 ENSE00000401072
   [4]        X 99887538-99887565      - |    667148 ENSE00001849132
   [5]        X 99888402-99888536      - |    667149 ENSE00003554016
   ...      ...               ...    ... .       ...             ...
  [13]        X 99890555-99890743      - |    667156 ENSE00003512331
  [14]        X 99891188-99891686      - |    667158 ENSE00001886883
  [15]        X 99891605-99891803      - |    667159 ENSE00001855382
  [16]        X 99891790-99892101      - |    667160 ENSE00001863395
  [17]        X 99894942-99894988      - |    667161 ENSE00001828996
  -------
  seqinfo: 722 sequences (1 circular) from an unspecified genome

...
<63676 more elements>

SummarizedExperiment:“列”数据(样本/实验信息)

colData(airway)
DataFrame with 8 rows and 9 columns
           SampleName     cell      dex    albut        Run avgLength
             <factor> <factor> <factor> <factor>   <factor> <integer>
SRR1039508 GSM1275862  N61311     untrt    untrt SRR1039508       126
SRR1039509 GSM1275863  N61311     trt      untrt SRR1039509       126
SRR1039512 GSM1275866  N052611    untrt    untrt SRR1039512       126
SRR1039513 GSM1275867  N052611    trt      untrt SRR1039513        87
SRR1039516 GSM1275870  N080611    untrt    untrt SRR1039516       120
SRR1039517 GSM1275871  N080611    trt      untrt SRR1039517       126
SRR1039520 GSM1275874  N061011    untrt    untrt SRR1039520       101
SRR1039521 GSM1275875  N061011    trt      untrt SRR1039521        98
           Experiment    Sample    BioSample
             <factor>  <factor>     <factor>
SRR1039508  SRX384345 SRS508568 SAMN02422669
SRR1039509  SRX384346 SRS508567 SAMN02422675
SRR1039512  SRX384349 SRS508571 SAMN02422678
SRR1039513  SRX384350 SRS508572 SAMN02422670
SRR1039516  SRX384353 SRS508575 SAMN02422682
SRR1039517  SRX384354 SRS508576 SAMN02422673
SRR1039520  SRX384357 SRS508579 SAMN02422683
SRR1039521  SRX384358 SRS508580 SAMN02422677

SummarizedExperiment:实验总体信息(metadata)

metadata(airway)
[[1]]
Experiment data
  Experimenter name: Himes BE 
  Laboratory: NA 
  Contact information:  
  Title: RNA-Seq transcriptome profiling identifies CRISPLD2 as a glucocorticoid responsive gene that modulates cytokine function in airway smooth muscle cells. 
  URL: http://www.ncbi.nlm.nih.gov/pubmed/24926665 
  PMIDs: 24926665 

  Abstract: A 226 word abstract is available. Use 'abstract' method.

SummarizedExperiment:取子集

SummarizedExperiment 类的一个重要特征是元数据与实验数据的协调,例如想要剔除某个样本,那么单个操作即可完成对元数据和试验的处理,确保元数据和观察值保持同步。

# 只保留地塞米松处理过的样本
airway[, airway$dex == "trt"]
class: RangedSummarizedExperiment 
dim: 63677 4 
metadata(1): ''
assays(1): counts
rownames(63677): ENSG00000000003 ENSG00000000005 ... ENSG00000273492
  ENSG00000273493
rowData names(10): gene_id gene_name ... seq_coord_system symbol
colnames(4): SRR1039509 SRR1039513 SRR1039517 SRR1039521
colData names(9): SampleName cell ... Sample BioSample
# 数据框取子集方法依然适用
airway[1:5, 1:3]
class: RangedSummarizedExperiment 
dim: 5 3 
metadata(1): ''
assays(1): counts
rownames(5): ENSG00000000003 ENSG00000000005 ENSG00000000419
  ENSG00000000457 ENSG00000000460
rowData names(10): gene_id gene_name ... seq_coord_system symbol
colnames(3): SRR1039508 SRR1039509 SRR1039512
colData names(9): SampleName cell ... Sample BioSample

差异分析

差异分析又称为转录组分析、RNASeq。DESeq2edgeRlimma 可以说是做转录组差异分析的金标准,大多数转录组的文章都是用这三个 R 包进行差异分析的。

差异分析: 工具对比

R 包 输入数据类型 适用于 数学模型
DESeq2 原始计数数据 高通量测序数据 负二项分布模型
edgeR 原始计数数据 高通量测序数据 负二项分布模型
limma log 后的计数数据 标准化之后的测序数据、芯片数据 线性模型,通常假设基因表达数据服从正态分布
  • limma 要求数据满足正态分布或近似正态分布,但通常认为 Counts 数据不符合正态分布而服从泊松分布。所以对于 Counts 数据来说,用 limma 包进行差异分析,误差较大。
  • edgeR 差异分析速度快,得到的基因数目比较多,假阳性高。
  • DESeq2 差异分析速度慢,得到的基因数目比较少,假阴性高。

实际中根据自己的需求进行方法选择。也有一些研究采用取三者交集的方式:

GEO数据下载

GEOquery 用于从NCBI的基因表达综合数据库(Gene Expression Omnibus, GEO)下载和解析数据。只需要知道GEO实验编号即可下载

library(GEOquery)
# 下载的文件一般较大,需修改默认超时设置
options(timeout=999999)
# 选择一个数据集GSE7765演示,GSE7765中包括两个平台,两个数据集
if(T){
  gse <- getGEO("GSE7765", GSEMatrix = TRUE) 
}

show(gse)

##提取第一个数据集的表达矩阵
expm1<-exprs(gse[[1]])
head(expm1) 

##提取第一个数据集的相关信息
dim(pData(gse[[1]]))
metdata<-pData(gse[[1]])
metdata[1:5,1:5]
colnames(metdata)

TCGAbiolinks:查询(query)1

GDCquery(
  project,  
  data.category, 
  data.type,
  workflow.type,
  access,
  platform,
  barcode,
  data.format,
  experimental.strategy,
  sample.type
)
  • project:TCGA项目编号,通过getGDCprojects()$project_id获取所有项目id
  • data.category:数据分类,如Simple Nucleotide Variation(单核苷酸变异)、Transcriptome Profiling(转录组),可通过getProjectSummary(项目编号)查看
  • data.type:数据类型,如Gene Expression Quantification(表达谱数据)
  • workflow.type:工作流,如STAR - Counts(内含 Counts 、FPKM 和 FPKM-UQ 三种数据类型)
  • access:controlled或open(TCGA中有些数据是不公开的)
  • platform:测序平台,如 IlluminaGA_RNASeqV2
  • barcode:条码编号,可筛选感兴趣的样本
  • data.format:数据格式。(“VCF”, “TXT”, “BAM”,“SVS”,“BCR XML”,“BCR SSF XML”, “TSV”, “BCR Auxiliary XML”, “BCR OMF XML”, “BCR Biotab”, “MAF”, “BCR PPS XML”, “XLSX”)
  • experimental.strategy:实验路线(WXS, RNA-Seq, miRNA-Seq, Genotyping Array)
  • sample.type:样本类型

每项参数的可选参数可以在TCGA GDC Data Portal网站查看

查询举例:

# 查询转录组基因表达数据
query_exp <- GDCquery(
    project = "TCGA-COAD",
    data.category = "Transcriptome Profiling",
    data.type = "Gene Expression Quantification", 
    workflow.type = "STAR - Counts"
)
# 查询转录组miRNA表达数据+样本限制
query <- GDCquery(
  project = "TARGET-AML",
  data.category = "Transcriptome Profiling",
  data.type = "miRNA Expression Quantification",
  workflow.type = "BCGSC miRNA Profiling",
  barcode = c("TARGET-20-PARUDL-03A-01R","TARGET-20-PASRRB-03A-01R")
)
# 查询DNA拷贝数变异数据,限制原位肿瘤组织
query <- GDCquery(
   project = "TCGA-ACC",
   data.category =  "Copy Number Variation",
   data.type = "Masked Copy Number Segment",
   sample.type = c("Primary Tumor")
)
# 查询临床数据
query <- GDCquery(
    project = "TCGA-LUAD",
    data.category = "Clinical",
    file.type = "xml"
  )

TCGAbiolinks:下载和整理(downloading & preparing)

GDCQuery只是构建了一个查询对象,要真正下载数据还需执行GDCdownload()方法。数据下载后会保存在工作空间下的项目名同名目录中,需有足够的硬盘空间。

使用GDCdownload()下载数据

GDCdownload(query = query) #一般情况下只需传入GDCQuery构建的查询对象即可

使用GDCprepare()整理数据

GDCprepare(
  query,
  save = FALSE, # 是否保存结果
  save.filename, # 保存文件名,如data.RData
  directory = "GDCdata", #保存路径
  summarizedExperiment = TRUE, # 是否以summarizedExperiment对象格式保存
  remove.files.prepared = FALSE, # 删除prepare文件
  ...
)

一般情况下传入query对象即可

data <- GDCprepare(query = query)

TCGAbiolinks:数据分析1

只使用TCGAbiolinks的就能完成差异分析整套标准工作流,其中主要的方法:

  • TCGAanalyze_Preprocessing :数据处理
  • TCGAanalyze_Normalization :标准化
  • TCGAanalyze_Filtering:过滤/筛选
  • TCGAanalyze_DEA :使用edgeR完成差异基因筛选

除了上面列出的,TCGAbiolinks还能进一步完成富集分析(TCGAanalyze_EAcomplete/TCGAvisualize_EAbarplot)、生存分析(TCGAanalyze_survival/TCGAanalyze_SurvivalKM)、甲基化分析(TCGAanalyze_DMR)、平均甲基化分析(TCGAvisualize_meanMethylation)、基因表达和甲基化关联分析(TCGAvisualize_starburst);以及绘制热图(TCGAvisualize)、火山图(TCGAvisualize_Volcano)、主成分分析及绘图(TCGAvisualize_PCA)等工作,几乎涵盖了RNA-Seq流程的方方面面。

CancerProject <- "TCGA-BRCA"
DataDirectory <- paste0("../GDC/",gsub("-","_",CancerProject))
FileNameData <- paste0(DataDirectory, "_","HTSeq_Counts",".rda")

query <- GDCquery(project = CancerProject,
                  data.category = "Transcriptome Profiling",
                  data.type = "Gene Expression Quantification", v
                  workflow.type = "HTSeq - Counts")

samplesDown <- getResults(query,cols=c("cases"))

dataSmTP <- TCGAquery_SampleTypes(barcode = samplesDown,
                                  typesample = "TP")

dataSmNT <- TCGAquery_SampleTypes(barcode = samplesDown,
                                  typesample = "NT")
dataSmTP_short <- dataSmTP[1:10]
dataSmNT_short <- dataSmNT[1:10]

queryDown <- GDCquery(project = CancerProject, 
                      data.category = "Transcriptome Profiling",
                      data.type = "Gene Expression Quantification", 
                      workflow.type = "HTSeq - Counts", 
                      barcode = c(dataSmTP_short, dataSmNT_short))

GDCdownload(query = queryDown,
            directory = DataDirectory)

dataPrep <- GDCprepare(query = queryDown, 
                       save = TRUE, 
                       directory =  DataDirectory,
                       save.filename = FileNameData)

dataPrep <- TCGAanalyze_Preprocessing(object = dataPrep, 
                                      cor.cut = 0.6,
                                      datatype = "HTSeq - Counts")                      

dataNorm <- TCGAanalyze_Normalization(tabDF = dataPrep,
                                      geneInfo = geneInfoHT,
                                      method = "gcContent") 

boxplot(dataPrep, outline = FALSE)

boxplot(dataNorm, outline = FALSE)

dataFilt <- TCGAanalyze_Filtering(tabDF = dataNorm,
                                  method = "quantile", 
                                  qnt.cut =  0.25)   

dataDEGs <- TCGAanalyze_DEA(mat1 = dataFilt[,dataSmTP_short],
                            mat2 = dataFilt[,dataSmNT_short],
                            Cond1type = "Normal",
                            Cond2type = "Tumor",
                            fdr.cut = 0.01 ,
                            logFC.cut = 1,
                            method = "glmLRT")  

基因组序列注释包

org.db系列包是Bioconductor项目中的一组R包,它们为各种生物物种提供了基因组注释信息的数据库。这些包通常以org.XXX.eg.db的格式命名,其中XXX代表物种的简称。

物种 org.db
按蚊(Anopheles) org.Ag.eg.db
拟南芥(Arabidopsis) org.At.tair.db
牛(Bovine) org.Bt.eg.db
蠕虫(Caenorhabditis elegans) org.Ce.eg.db
犬(Canine) org.Cf.eg.db
苍蝇(Drosophila melanogaster) org.Dm.eg.db
斑马鱼(Danio rerio) org.Dr.eg.db
大肠杆菌 strain K12(Escherichia coli strain K12) org.EcK12.eg.db
大肠杆菌 strain Sakai(Escherichia coli strain Sakai) org.EcSakai.eg.db
鸡(Gallus gallus) org.Gg.eg.db
人(Homo sapiens) org.Hs.eg.db
小鼠(Mus musculus) org.Mm.eg.db
恒河猴(Macaca mulatta) org.Mmu.eg.db
疟原虫(Plasmodium falciparum) org.Pf.plasmo.db
黑猩猩(Pan troglodytes) org.Pt.eg.db
大鼠,褐家鼠(Rattus norvegicus) org.Rn.eg.db
酵母(Saccharomyces cerevisiae) org.Sc.sgd.db
猪(Sus scrofa) org.Ss.eg.db
爪蟾(Xenopus) org.Xl.eg.db

org.db包使用

org.db包经常用来进行基因ID的转换,比如大家都熟悉的的entrez ID 和ensembl 数据库的ID。

library(org.Hs.eg.db)
keytypes(org.Hs.eg.db)
 [1] "ACCNUM"       "ALIAS"        "ENSEMBL"      "ENSEMBLPROT"  "ENSEMBLTRANS"
 [6] "ENTREZID"     "ENZYME"       "EVIDENCE"     "EVIDENCEALL"  "GENENAME"    
[11] "GENETYPE"     "GO"           "GOALL"        "IPI"          "MAP"         
[16] "OMIM"         "ONTOLOGY"     "ONTOLOGYALL"  "PATH"         "PFAM"        
[21] "PMID"         "PROSITE"      "REFSEQ"       "SYMBOL"       "UCSCKG"      
[26] "UNIPROT"     

使用select()函数就可以同时将一种ID转换成多种类型的ID,非常方便

ensids <- c("ENSG00000130720", "ENSG00000103257", "ENSG00000156414","ENSG00000144644", "ENSG00000159307", "ENSG00000144485")
 
result <- select(org.Hs.eg.db, keys=ensids, columns=c("SYMBOL", "GENENAME","ENTREZID"), keytype="ENSEMBL")
class(result)
[1] "data.frame"

mapIds()函数主要用于将一个ID类型映射到另一个ID类型

result <- mapIds(org.Hs.eg.db, keys=ensids, column='SYMBOL', keytype='ENSEMBL')
class(result)
[1] "character"

Part03 R语言与生信绘图

热图(Pheatmap)

热图是一种将矩阵数据转换成颜色色调的常用的可视化方法,其中每个单元格对应数据的某些属性,属性的值通过颜色映射转换为不同色调并按规则填充单元格。在表达组数据中,色块颜色经常被映射到基因表达量。

使用pheatmap包绘制热图

library(pheatmap)
set.seed(123)
nr1 = 4; nr2 = 8; nr3 = 6; nr = nr1 + nr2 + nr3
nc1 = 6; nc2 = 8; nc3 = 10; nc = nc1 + nc2 + nc3
mat = cbind(rbind(matrix(rnorm(nr1*nc1, mean = 1,   sd = 0.5), nr = nr1),
          matrix(rnorm(nr2*nc1, mean = 0,   sd = 0.5), nr = nr2),
          matrix(rnorm(nr3*nc1, mean = 0,   sd = 0.5), nr = nr3)),
    rbind(matrix(rnorm(nr1*nc2, mean = 0,   sd = 0.5), nr = nr1),
          matrix(rnorm(nr2*nc2, mean = 1,   sd = 0.5), nr = nr2),
          matrix(rnorm(nr3*nc2, mean = 0,   sd = 0.5), nr = nr3)),
    rbind(matrix(rnorm(nr1*nc3, mean = 0.5, sd = 0.5), nr = nr1),
          matrix(rnorm(nr2*nc3, mean = 0.5, sd = 0.5), nr = nr2),
          matrix(rnorm(nr3*nc3, mean = 1,   sd = 0.5), nr = nr3))
   )
mat = mat[sample(nr, nr), sample(nc, nc)] # random shuffle rows and columns
rownames(mat) = paste0("gene", seq_len(nr))
colnames(mat) = paste0("sample", seq_len(nc))
pheatmap(mat,color = colorRampPalette(c('#00ff00','#000000','#ff0000'))(50))

热图(Pheatmap)

火山图(Volcano Plot)

我们使用内置数据集airway差异分析结果进行演示:

diff <- read.csv("http://roypub.biovr.cc/202411111700084.csv",header = T)
head(diff)
       X    baseMean log2FoldChange      lfcSE       stat       pvalue
1 TSPAN6 710.0826548    -0.37891829 0.09820208 -3.8612391 0.0001128134
2   TNMD   0.0000000             NA         NA         NA           NA
3   DPM1 521.2234513     0.19750594 0.10905322  1.8129569 0.0698384691
4  SCYL3 237.5957517     0.03157256 0.13799860  0.2319739 0.8165582676
5  FIRRM  58.0322755    -0.08912899 0.25055644 -0.3225358 0.7470468003
6    FGR   0.3195067    -0.08486965 0.15229370 -0.3951174 0.6927562146
          padj
1 0.0008878468
2           NA
3 0.1934319794
4 0.9148562178
5 0.8777757931
6           NA

使用EnhancedVolcano包方便的绘制火山图:

library(EnhancedVolcano)
EnhancedVolcano(diff,
  lab = diff$X,
  x = 'log2FoldChange',
  y = 'pvalue')

PCA图(PCA Plot)

使用ggbiplot绘制PCA图

library(ggbiplot)

data(iris)
iris.pca <- prcomp (~ Sepal.Length + Sepal.Width + Petal.Length + Petal.Width,
                    data=iris,
                    scale. = TRUE)
ggbiplot(iris.pca, obs.scale = 1, var.scale = 1,
         groups = iris$Species, point.size=2,
         varname.size = 5, 
         varname.color = "black",
         varname.adjust = 1.2,
         ellipse = TRUE, 
         var.axes = FALSE,
         circle = TRUE) +
  labs(fill = "Species", color = "Species") +
  theme_minimal(base_size = 14) +
  theme(legend.direction = 'horizontal', legend.position = 'top')

PCA图(PCA Plot)

韦恩图(Venn Diagram)

韦恩图(Venn Diagram)是一种常用于数据可视化的图表类型,它能够直观地展示数据集之间的交集和差异。

可以使用ggvenn绘制韦恩图

library(ggvenn)

d <- tibble(value   = c(1,     2,     3,     5,     6,     7,     8,     9),
            `Set 1` = c(TRUE,  FALSE, TRUE,  TRUE,  FALSE, TRUE,  FALSE, TRUE),
            `Set 2` = c(TRUE,  FALSE, FALSE, TRUE,  FALSE, FALSE, FALSE, TRUE),
            `Set 3` = c(TRUE,  TRUE,  FALSE, FALSE, FALSE, FALSE, TRUE,  TRUE),
            `Set 4` = c(FALSE, FALSE, FALSE, FALSE, TRUE,  TRUE,  FALSE, FALSE))
ggvenn(d, c("Set 1", "Set 2"))           # draw two-set venn

ggvenn(d, c("Set 1", "Set 2", "Set 3"))  # draw three-set venn

ggvenn(d)